Isolation, characterization, and alginate hydrogel delivery of a Klebsiella aerogenes bacteriophage and its impact on biofilm degradation [0.03%]
枯草杆菌噬菌体的分离、表征、及其藻酸盐水凝胶递送方式对生物被膜降解的影响
Istiaque Zaeem,Shakhinur Islam Mondal,Raphael Kabir Niloy et al.
Istiaque Zaeem et al.
Multidrug-resistant Klebsiella aerogenes poses a significant clinical challenge due to its antimicrobial resistance and biofilm-forming capacity in chronic wounds and device-associated infections. Bacteriophage therapy offers a promising al...
Bacterial neurotoxins: The snake venoms of the microbial world-a clinical and bioengineering approach [0.03%]
细菌神经毒素：微生物王国的蛇毒——临床和生物工程视角
Hanieh Banaeyoun,Yaser Solhi Digehsara,Behrouz Golichenari
Hanieh Banaeyoun
The central and peripheral nervous systems constitute highly organized and dynamic networks that rely on precise regulation of synaptic transmission, membrane integrity, cytoskeletal stability, and intracellular signaling. Disruption of the...
Disentangling non-specific and condition-specific transcriptomic responses: A framework from heat stress in yeast [0.03%]
解剖非特异性与条件特异性的转录组响应：基于酵母热应力的框架研究
Stéphane Guyot,Lucie Bertheau,Jennifer Dumont et al.
Stéphane Guyot et al.
A central challenge in biology is to distinguish transcriptional responses that recur across heterogeneous stress conditions from those that are specific to particular experimental contexts. Here, using Saccharomyces cerevisiae as a model s...
Fish gut-water interface as a hotspot for the dissemination of antibiotic resistance genes across natural and aquaculture systems [0.03%]
鱼肠道-水界面作为自然和水产系统中抗生素抗性基因传播的热点地区
Padma Dolkar,L Themchuirin,Nongmaithem Sonia et al.
Padma Dolkar et al.
Freshwater ecosystems are important reservoirs and transmission pathways for antibiotic resistance genes (ARGs), yet host-mediated microbial selection and anthropogenic pressure on fish gut resistome remain poorly characterised, especially ...
Qdr3 Coordinates cellular homeostasis, mitochondrial remodeling, and virulence in Candidozyma auris (Candida auris) [0.03%]
Qdr3调节白色念珠菌细胞稳态、线粒体重塑和毒力
Isadora F Munhoz da Rocha,Craig L Ennis,Bruno Aa Romagnoli et al.
Isadora F Munhoz da Rocha et al.
Qdr3 acts as a global regulator in Candidozyma auris (Candida auris), coordinating mitochondrial function and cell-surface architecture. Loss of qdr3 causes major cellular reprogramming, increasing mitochondrial activity and virulence, high...
Seed bacterial microbiota: transmission, community assembly, and prospects for engineering heritable functions in crops [0.03%]
种子细菌微生态：传播、群落构建及作物遗传功能工程应用前景展望
Hamed Azarbad,Mehrdad Alizadeh
Hamed Azarbad
Seeds represent specialized, low-biomass microbial niches that facilitate the transmission of the plant-associated microbiota from one generation to another. Residing as both epiphytes and endophytes, seed-associated bacteria contribute to ...
Wannes Van Holm,Julie Marynissen,Lien Van Campenhout et al.
Wannes Van Holm et al.
The clinical application of probiotics for oral health is increasing, yet their colonization dynamics remain poorly understood. This study investigated whether administration timing, strain origin, and host-specific factors influence oral p...
Dynamic metabolic regulation and vitamin C-mediated inhibition of Vibrio splendidus persisters by single-cell Raman spectroscopy [0.03%]
单细胞拉曼光谱法检测发光弧菌休眠体的代谢调节及维生素C抑制效应
Meishan Qin,Yuehui He,Yuanyuan Zhou et al.
Meishan Qin et al.
Persister cells, a multidrug-tolerant bacterial subpopulation, pose challenges to disease control, with research hindered by technical limitations. In this study, single-cell Raman spectroscopy (SCRS) combined with heavy water (D2O) labelin...
Ecological and functional succession of the microbial community during pit mud maturation in Nongxiangxing Baijiu [0.03%]
宁乡型白酒窖泥微生物群落的生态与功能演替分析
Lei Tian,Ji Qin,Yue Deng et al.
Lei Tian et al.
Pit mud (PM) microbiota play a vital role in Baijiu flavor formation, yet its ecological and functional succession during maturation remains incompletely elucidated. Here, physicochemical profiling, amplicon sequencing, and metagenomics wer...
Sublethal oxytetracycline and copper exposure alters rRNA gene copy number, expression, and intragenomic polymorphism in ciliates [0.03%]
次致死量的四环素和铜暴露会改变纤毛虫的rDNA拷贝数、表达及基因组多态性
Songbao Zou,Rao Fu,Huiwen Deng et al.
Songbao Zou et al.
Ribosomal RNA (rRNA) genes serve as foundational markers for microbial eukaryotic diversity assessment, yet their responses to environmental stressors remain underexplored. This study examined the effects of sublethal oxytetracycline and Cu...