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Dynamic metabolic regulation and vitamin C-mediated inhibition of Vibrio splendidus persisters by single-cell Raman spectroscopy

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Persister cells, a multidrug-tolerant bacterial subpopulation, pose challenges to disease control, with research hindered by technical limitations. In this study, single-cell Raman spectroscopy (SCRS) combined with heavy water (D2O) labeling was employed to ex... ...