Voluntary wheel running in male mice mitigates select hyperglycemia-induced depressive-like behaviors and modulates BDNF and Tnf in a brain region-specific manner [0.03%]
自愿跑步缓解雄性小鼠特选的高血糖诱导的抑郁行为，并以脑区特异性的方式调节BDNF和Tnf
Laura E Kusumo,Grace A Reese,Matthew J Folh et al.
Laura E Kusumo et al.
Diabetes is associated with an increased risk for depression. Emerging data suggests this effect is partly mediated by hyperglycemia-associated neuroinflammation and decreased BDNF. While exercise reduces depressive symptoms in other models...
Childhood and contemporaneous inflammation in depersonalisation and derealisation: Longitudinal evidence from the Avon Longitudinal Study of Parents and Children [0.03%]
儿童和同时期炎症在人格解体和现实解体中的作用：来自艾冯父母与子女纵向研究的纵向证据
Evelyn Dilkes,Helge Gillmeister,Katie Daughters
Evelyn Dilkes
Background: Depersonalisation (DP) and derealisation (DR) are dissociative experiences that disrupt an individual's perception of themself and their environment. Recent evidence suggests a potential role for inflammatory ...
Brain dynamics of attentional, default-mode and limbic networks are disrupted at rest in post-COVID-19 syndrome [0.03%]
新冠病毒后综合征患者的注意网络、默认模式网络和边缘系统在静息态下的功能异常
Marie-Stephanie Cahart,Owen O&#x; Daly,Ziyuan Cai et al.
Marie-Stephanie Cahart et al.
Background: Post-COVID-19 Syndrome (PCS) is characterised by persistent fatigue, cognitive impairments, and affective symptoms, yet its underlying neural mechanisms remain poorly understood. While static neuroimaging stud...
Effects of neuroinflammation and neurotrophic factors on mental health of people with axial spondyloarthritis [0.03%]
神经炎症和神经营养因子对轴性脊柱关节炎患者精神健康的影响
Markéta Hušáková,Karel Pavelka,Karolína Kuchaříková et al.
Markéta Hušáková et al.
Introduction: Mood and anxiety disturbances can aggravate axial spondyloarthritis (axSpA). This study investigated the relationship between depression, anxiety, disease activity, systemic inflammation, and neurotrophins, ...
Immunomodulatory effects of cannabis use: a multi-omics study in people living with HIV [0.03%]
大麻使用的免疫调节作用：与艾滋病毒人群的多组学研究
Elise M G Meeder,Jiang Xun,Adriana Navas et al.
Elise M G Meeder et al.
Background: Cannabis is one of the most commonly used substances worldwide. Cannabinoids are known to have anti-inflammatory effects. However, cannabis is mainly smoked, resulting in exposure to reactive particles, toxins...
Gut microbiota restructured by social isolation: Evidence for sex-specific response patterns [0.03%]
社交隔离重构肠道微生物群：证据表明性别特异性响应模式
Kathleen Fallon,Siva Reddy Challa,Casimir A Fornal et al.
Kathleen Fallon et al.
Background: Both post-weaning social isolation and gut microbiota community structure have been independently associated with physical and mental health outcomes. However, sex differences are often overlooked in biology, ...
Sellar-parasellar Epstein-Barr virus associated smooth muscle tumour mimicking a pituitary adenoma: A case report [0.03%]
与垂体腺瘤相似的分泌-寄生垂体 Epstein-Barr 病毒相关的平滑肌肿瘤一例报告
E Saravanakumar,A Vastani,A Merve et al.
E Saravanakumar et al.
Epstein-Barr virus-associated smooth muscle tumours (EBV-SMTs) are rare mesenchymal neoplasms. These tumours almost exclusively occur in immunocompromised individuals, with the three main causes being Human Immunodeficiency Virus (HIV), pos...
An externally validated machine learning algorithm for predicting mental and physical health outcomes three months post-hospitalization for severe viral infection with SARS-CoV-2 [0.03%]
一项经外部验证的机器学习算法 用于预测严重病毒感染(SARS-CoV-2)住院后三个月的心理和生理健康结果
Katharina Schultebraucks,Sapir Gershov,Felix Fischer et al.
Katharina Schultebraucks et al.
Many individuals hospitalized due to severe viral infections develop mental and physical sequelae, which could potentially be prevented by targeted interventions for those at risk. Our goal was to develop and externally validate an algorith...
Central nervous system resilience to cyclophosphamide: preserved behavior, astrocytes and LGALS3 expression in immunosuppressed mice [0.03%]
环磷酰胺中央神经系统耐受性：免疫抑制小鼠中行为、星形胶质细胞和LGALS3表达的保持
Rogério Aires,Alex de Camargo Coque,Lucas Maruchi Delapena Silva et al.
Rogério Aires et al.
Background: Cyclophosphamide is widely used as an immunosuppressive agent in experimental models. However, its potential effect on central nervous system (CNS) function and behavior may confound studies investigating neur...
Intersectional effects of race/ethnicity, sex, and APOE4 on plasma inflammatory profiles in Hispanic and non-Hispanic white adults [0.03%]
种族、民族、性别和APOE4对非西班牙裔白人和西班牙裔成年人血浆炎症谱型的交叉作用效应
J A Contreras,N E Ortega,C A Hayes et al.
J A Contreras et al.
Background: Despite known links between inflammation and Alzheimer's disease (AD), little is understood about how inflammatory processes vary across racial/ethnic and sex groups, particularly in relation to the major gene...