Inside out: TNFa-RII and sexualized drug use in acute HIV predicts persistent depressive symptoms despite antiretroviral therapy [0.03%]
外源性TNFa-RII和急性HIV感染患者的性行为与持续性抑郁症状相关性研究尽管使用了抗逆转录病毒疗法
Jennifer V Chavez,Jacob Bolzenius,Phillip Chan et al.
Jennifer V Chavez et al.
Objective: Although pathophysiologic alterations during acute HIV infection (AHI) may have long-term neuropsychiatric consequences, scant research has examined biobehavioral predictors of distinct depressive symptom traje...
Detection of autoantibodies against Interferon Type I in patients with autochthonous West Nile Virus encephalitis [0.03%]
西尼罗病毒引起的自体炎性反应中针对I型干扰素的自身抗体的鉴定
Jan Braune,Lorenz Pechstein,Christian Meisel et al.
Jan Braune et al.
West Nile virus (WNV) is a neurotropic flavivirus that has become a global concern because of its rapid geographical spread and its capacity to cause severe disease in humans. Although often asymptomatic, infection can lead to life-threaten...
Outness predicts greater leukocyte telomere length in sexually minoritized men with HIV who use methamphetamine [0.03%]
性取向少数男性HIV感染者使用冰毒与白细胞端粒长度有关
Renessa S Williams,Ariana Johnson,Michael Miller-Perusse et al.
Renessa S Williams et al.
Objective: This longitudinal study aimed to examine the associations of sexual minority stress and outness with leukocyte telomere length across time among sexually minority men (SMM) with HIV who use methamphetamine. ...
Progranulin modulates inflammatory responses to immune challenges by suppressing circulating cytokine levels [0.03%]
前列腺素D2通过抑制循环细胞因子水平调节对免疫刺激的炎症反应
Takashi Matsuwaki,Keitaro Yamanouchi,Masugi Nishihara
Takashi Matsuwaki
Progranulin (PGRN) is a multifunctional growth factor that is widely expressed throughout the body. It has recently been reported that PGRN haploinsufficiency is a major factor causing frontotemporal lobar dementia. Subsequently, many studi...
Associations between the gut microbiota at one-year and neurodevelopment in children from the SEPAGES cohort [0.03%]
SEPAGES队列中一岁婴儿肠道菌群与幼儿神经发育的关系
Aline Davias,Sarah Lyon-Caen,Nina Iszatt et al.
Aline Davias et al.
Fundamental research indicates a communication between the gut microbiota and the central nervous system, referred to as the microbiota-gut-brain axis. This link is little characterized in humans in the general population. We prospectively ...
Adolescent depression, childhood maltreatment, and the immune system; a role for epigenetic aging? [0.03%]
青少年抑郁症、儿童虐待与免疫系统；表观遗传衰老的作用？
Marieke S Tollenaar,Nicole Creasey,Mirjam C M Wever et al.
Marieke S Tollenaar et al.
Background: Childhood maltreatment is a major risk factor for the development of depression, as well as for imbalances in the immune system, including chronic low-grade inflammation. Less is known about potential immune i...
The impact of acute COVID-19 symptoms on insomnia: A longitudinal study among medical students [0.03%]
急性COVID-19症状对失眠的影响——一项针对医学院学生的纵向研究
Yue Zhu,Xiaoyang Qin,Yuhong Lu et al.
Yue Zhu et al.
Objective: The COVID-19 pandemic has profoundly disrupted global mental health. Medical students, already vulnerable to high stress, experience heightened psychological distress. This study aimed to investigate the associ...
Impact of maternal microbiota imbalance during pregnancy on fetal cerebral neurodevelopment: Is there a link to certain autistic disorders? [0.03%]
孕期母体微生物群失调对胎儿脑神经发育的影响：与自闭症谱系障碍有关吗？
Sylvie Mavel,Léa Pellé,Christian R Andres
Sylvie Mavel
Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with a heterogeneous group of psychiatric disorders primarily characterized by impairments in communication and social interactions. ASD typically emerges around 18 ...
Maternal immune activation and antibiotics affect offspring neurodevelopment, behaviour, and microbiome [0.03%]
母体免疫激活和抗生素影响后代神经发育、行为及微生物群
Clara Deady,Jamie FitzGerald,Nirit Kara et al.
Clara Deady et al.
In utero exposure to an increased level of maternal inflammation or a disrupted maternal gut microbiome during pregnancy have been linked to several neurodevelopmental disorders in the offspring. Despite the strong links between these two a...
Circulating short chain fatty acids are associated with depression severity and predict remission from major depressive disorder [0.03%]
循环中短链脂肪酸与抑郁症严重程度相关，并可预测重度抑郁障碍的缓解
Carmen Schiweck,Boushra Dalile,Alice Balliet et al.
Carmen Schiweck et al.
Background: Short-chain fatty acids (SCFAs) have been shown to improve depression-like behavior in animal models. However, their predictive value for depression outcomes in humans remains unclear. If SCFAs are predictive,...