A porcine model of thoracic aortic aneurysms created with a retrievable drug infusion stent graft mirrors human aneurysm pathophysiology [0.03%]
一种用可取回的药物灌注支架移植物创建的胸主动脉瘤猪模型与人类动脉瘤病理生理学相似
Dahlia M Kenawy,Jordan F Stafford,Foued Amari et al.
Dahlia M Kenawy et al.
Objective: Aneurysm pathophysiology remains poorly understood, in part from the disparity of murine models with human physiology and the requirement for invasive aortic exposure to apply agents used to create aneurysm mod...
Small apolipoprotein(a) isoforms may predict primary patency following peripheral arterial revascularization [0.03%]
小型载脂蛋白（a）等位基因可预测外周动脉重建术后的主要通畅率
Marianna Pavlyha,Madeleine Hunter,Roman Nowygrod et al.
Marianna Pavlyha et al.
Background: High lipoprotein (a) [Lp(a)] is associated with adverse limb events in patients undergoing lower extremity revascularization. Lp(a) levels are genetically pre-determined, with LPA gene encoding for two apolipo...
Thijs J Sluiter,Lucinda Cruddas,Federica Ninno et al.
Thijs J Sluiter et al.
The Basic Vascular Science (BVS) meeting was set up to provide a forum for researchers and clinicians in the field to exchange knowledge and ideas and to foster cross-disciplinary collaborations. The BVS 2024 meeting was held in Berlin. Att...
Alan Dardik
Alan Dardik
Marianna Pavlyha,Alan Dardik
Marianna Pavlyha
Serum detection of blood brain barrier injury in subjects with a history of stroke and transient ischemic attack [0.03%]
既往有卒中和短暂性脑缺血发作病史患者血脑屏障损伤的血清标志物检测
Scott French,Juan Arias,Ikeoluwapo Bolakale-Rufai et al.
Scott French et al.
Objective: Stroke and transient ischemic attack may have long-term negative effects on the blood-brain barrier (BBB) and promote endothelial inflammation, both of which could increase neurodegeneration and dementia risk b...
Ultrasound elastography to quantify average percent pressure-normalized strain reduction associated with different aortic endografts in 3D-printed hydrogel phantoms [0.03%]
声弹性成像技术量化不同主动脉覆膜支架在三维打印水凝胶体模中压力归一化应变减少百分比的平均值
Dakota W Gonring,Zachary R Zottola,Adnan A Hirad et al.
Dakota W Gonring et al.
Objective: Strain has become a viable index for evaluating abdominal aortic aneurysm stability after endovascular aneurysm repair (EVAR). In addition, literature has shown that healthy aortic tissue requires a degree of s...
Dyslipidemia impairs collateral artery formation after hindlimb ischemia: Adding insult to injury [0.03%]
高脂血症损害后肢缺血后的侧支动脉形成：雪上加霜式的打击
Ali H Hakim,Luke Brewster
Ali H Hakim
Hypercholesterolemia impairs collateral artery enlargement by ten-eleven translocation 1-dependent hematopoietic stem cell autonomous mechanism in a murine model of limb ischemia [0.03%]
高胆固醇通过Tet1依赖的造血干细胞自主机制损害四肢缺血小鼠模型侧支动脉的扩张能力
Jinglian Yan,Guodong Tie,Amanda Tutto et al.
Jinglian Yan et al.
Objective: The extent of collateral artery enlargement determines the risk of limb loss due to peripheral arterial disease. Hypercholesterolemia impairs collateral artery enlargement, but the underlying mechanism remains ...
Hyperoxia impairs induced pluripotent stem cell-derived endothelial cells and drives an atherosclerosis-like transcriptional phenotype [0.03%]
过度吸氧损害诱导多能干细胞来源的内皮细胞并导致类似动脉粥样硬化的转录表型
Sean M Carr,Katherine Owsiany,Ottis Scrivner et al.
Sean M Carr et al.
Background: Induced pluripotent stem cells (iPSCs) directed to endothelial identity (iPSC-ECs) are emerging as a potent tool for regenerative medicine in vascular disease. However, iPSC-ECs lose expression of key identity...