Serum levels of neurofilament light chain (NfL) and glial fibrillary acid protein (GFAP) in patients with asymptomatic and symptomatic carotid artery stenosis [0.03%]
无症状和有症状颈动脉狭窄患者的神经丝轻链(NfL)和胶质纤维酸性蛋白(GFAP)水平
Robin Jansen,Markus U Wagenhäuser,Tristan Kölsche et al.
Robin Jansen et al.
Objective: The treatment of carotid artery stenosis (CAS) for stroke prevention is a matter of debate due to conflicting data, missing recent data, and advances in medical treatment options but also in interventional tech...
Proteomic signatures of carotid plaque vulnerability: Proteolysis, inflammation, metabolic reprogramming, and lipid dysregulation [0.03%]
易损颈动脉斑块的蛋白质组特征：蛋白水解、炎症、代谢重编程和脂质紊乱
Camilo Polania Sandoval,James F Meschia,Mercedes Prudencio et al.
Camilo Polania Sandoval et al.
Background: Carotid plaque vulnerability is a current feature that aids in the decision-making for ischemic stroke risk. Proteomic analysis of plaque tissue can reveal molecular indicators of instability that complement i...
A narrative review of recent literature of circulating biomarkers of abdominal aortic aneurysm [0.03%]
近期关于腹主动脉瘤循环生物标志物文献的叙述性回顾
Yae Hyun Rhee,Joshua M Spin,Philip S Tsao
Yae Hyun Rhee
Objective: Abdominal aortic aneurysms (AAAs) arise through complex pathogenesis, and good methods of risk stratification have proved elusive. Further, the lack of medical options short of surgery for treatment, and the re...
Fatih Kizilyel
Fatih Kizilyel
The future is bright [0.03%]
未来是光明的
Alan Dardik
Alan Dardik
Montelukast attenuates abdominal aortic aneurysm in rats: Anti-inflammatory and antioxidant effects [0.03%]
蒙赖卢塔斯能缓解大鼠腹主动脉瘤：抗炎和抗氧化作用
Gözde Tekin,Özge Çevik,Şule Çetinel et al.
Gözde Tekin et al.
Objective: Oxidative stress and inflammation are widely recognized as central mechanisms in the pathogenesis of abdominal aortic aneurysm. This study sought to examine the potential protective properties of montelukast in...
Role of adipocyte angiotensinogen or angiotensin type 1a receptors in the development of diet-induced atherosclerosis or angiotensin II-induced abdominal aortic aneurysms [0.03%]
脂肪细胞血管紧张素原或血管紧张素Ⅱ型受体在饮食诱导的动脉粥样硬化和血管紧张素II诱导的腹主动脉瘤发展中的作用
Yasir AlSiraj,Kelly Putnam,Seth I Brunner et al.
Yasir AlSiraj et al.
Objective: Adipocytes express renin-angiotensin system (RAS) components, including angiotensinogen (Agt), the precursor to angiotensin II (AngII), and the angiotensin type 1a receptor (AT1aR). The RAS contributes to ather...
Galectin-3 is dispensable for thoracic aortic aneurysmal formation and rupture in mice [0.03%]
鼠胸主动脉瘤形成和破裂不需要半乳糖凝集素-3
Nithya Ramesh,Edward Downey,Sudheer Kumar Kanumuri et al.
Nithya Ramesh et al.
Thoracic aortic aneurysm (TAA) development involves disruption of extracellular matrix structural proteins such as collagen and elastin. An increased level of Galectin-3 (Gal-3), a β-galactoside-binding lectin, was reported in ascending ao...
Contrast-enhanced ultrasound microbubble uptake and abnormal plasma biomarkers are seen in patients with abdominal aortic aneurysms [0.03%]
腹主动脉瘤患者的声学造影和异常血浆生物标志物检测结果
Adham N Abou Ali,Patrick Cherfan,Ashraf G Taha et al.
Adham N Abou Ali et al.
Objective: Abdominal aortic aneurysm (AAA) growth is unpredictable. We hypothesize that contrast-enhanced ultrasound (CEUS) imaging and plasma inflammatory biomarkers (PIBs) may detect AAA wall inflammation. ...