Inhibition of angiotensin-induced aortic aneurysm by metformin in apolipoprotein E-deficient mice [0.03%]
代谢型抑制ANG II诱导的载脂蛋白E缺乏小鼠主动脉瘤形成
Anne Kunath,Jon Unosson,Malou Friederich-Persson et al.
Anne Kunath et al.
Objective: Metformin is associated with a reduced incidence and growth of abdominal aortic aneurysms (AAAs). The aim of the present study was to investigate the inhibitory effects of metformin on AAA development and possi...
Gangrene, revascularization, and limb function improved with E-selectin/adeno-associated virus gene therapy [0.03%]
E-选择素/腺相关病毒基因治疗改善坏死，血液恢复及肢体功能
Hallie J Quiroz,Punam P Parikh,Roberta M Lassance-Soares et al.
Hallie J Quiroz et al.
Objective: Novel therapeutic angiogenic concepts for critical limb ischemia are still needed for limb salvage. E-selectin, a cell-adhesion molecule, is vital for recruitment of the stem/progenitor cells necessary for neov...
A versatile technique for high-resolution three-dimensional imaging of human arterial segments using microcomputed tomography [0.03%]
使用微计算机断层扫描对人动脉段进行高分辨率三维成像的一种多用途技术
Scott T Robinson,Ruth E Levey,Rachel Beatty et al.
Scott T Robinson et al.
Background: Quantitative methods for evaluating microstructure of arterial specimens typically rely on histologic techniques that involve random sampling, which cannot account for the unique spatial distribution of featur...
Alan Dardik
Alan Dardik
Luke Brewster,Alan Dardik
Luke Brewster
Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry [0.03%]
全基因组测序在具有欧洲血统的患者中鉴定与胸主动脉壁缺陷和腹主动脉瘤特异性相关的位点
Grace H Miner,Alan E Renton,Ella Taubenfeld et al.
Grace H Miner et al.
Objective: The objective of this study was to better understand the pathophysiology and underlying genetic mechanisms behind two abdominal aortic aneurysm (AAA) subtypes using computed tomographic imaging in combination w...
K-134, a phosphodiesterase 3 inhibitor, reduces vascular inflammation and hypoxia, and prevents rupture of experimental abdominal aortic aneurysms [0.03%]
K-134，一种磷酸二酯酶3抑制剂，可减少血管炎症和缺氧，并防止实验性腹主动脉瘤破裂
Naoki Unno,Hiroki Tanaka,Tatsuro Yata et al.
Naoki Unno et al.
Objective: Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease, which frequently results in fatal rupture; however, no pharmacologic treatment exists to inhibit AAA growth and prevent rupture. In this study,...
Cilostazol as a noninferiority pharmacologic option to paclitaxel in early intimal hyperplasia inhibition after venous balloon angioplasty in a rabbit model: a preliminary study [0.03%]
西洛他唑作为兔静脉球囊成形术早期内膜增生抑制药相比于紫杉醇的非劣性选择：初步研究
Rodrigo Lozano-Corona,Hugo Laparra-Escareno,Javier E Anaya-Ayala et al.
Rodrigo Lozano-Corona et al.
The development of venous intimal hyperplasia (VIH) has not been fully studied. At present, there are no drugs approved for VIH inhibition; to investigate such alternatives, we aimed to compare paclitaxel with cilostazol in VIH early inhibi...
Increased matrix metalloproteinase 9 activity correlates with flow-mediated intraluminal thrombus deposition and wall degeneration in human abdominal aortic aneurysm [0.03%]
人腹主动脉瘤中基质金属蛋白酶9活性增加与血流介导的管腔内血栓形成和血管壁退化相关
Annie A Ducas,David C S Kuhn,Lauren C Bath et al.
Annie A Ducas et al.
Objective: We have previously demonstrated that human abdominal aortic aneurysm (AAA) rupture occurs in zones of low wall shear stress where flow recirculation and intraluminal thrombus (ILT) deposition are increased. Mat...
Efficacy of antiseptic impregnation of aortic endografts with rifampicin compared to silver against in vitro contamination with four bacteria that frequently cause vascular graft infections [0.03%]
Rifampicin涂层的主动脉内移植物对比银离子涂层的抗四种常见导致血管移植物感染细菌的体外实验研究
Susanne Honig,Philipp Seeger,Holger Rohde et al.
Susanne Honig et al.
Objective: This in vitro study investigates the antimicrobial efficacy of impregnation of commercially available aortic endografts (EG) with rifampicin (RIF) and nanocolloidal silver. ...