Perivascular spaces, diffusion MRI markers and cognitive decline in cerebral small vessel disease [0.03%]
血管周围空间、弥散MRI标志物与脑小血管病患者的认知下降关系研究
Gemma Solé-Guardia,Hao Li,Jessica Lebenberg et al.
Gemma Solé-Guardia et al.
Background: MRI markers, including visible perivascular spaces (PVS), diffusion tensor image analysis along the perivascular space (DTI-ALPS) index, and peak width of skeletonized mean diffusivity (PSMD) may capture the e...
FDG-PET anterior cingulate cortex hypometabolism as a marker of cerebral small vessel disease in Alzheimer's and vascular cognitive impairment and dementia [0.03%]
氟脱氧葡萄糖正电子发射断层扫描前扣带回低代谢标志脑小血管病在阿尔茨海默病及血管性认知障碍和痴呆中的作用
Sarah T Thomas,Logesh Palanikumar,David G Darby et al.
Sarah T Thomas et al.
Background: The anterior cingulate cortex (ACC) is an important hub in the executive and salience networks. While fluorodeoxyglucose-positron emission tomography (FDG-PET) is valuable in dementia diagnosis, there is no FD...
Aging of neural stem cells and vascular dysfunction: mechanisms, interconnection, and therapeutic perspectives [0.03%]
神经干细胞老化和血管功能障碍：机制、关联及治疗前景
Khrystyna Duve,Volodymyr Lushchak,Svitlana Shkrobot
Khrystyna Duve
Background: Aging of the central nervous system is accompanied by a progressive decline in neuroplasticity, regenerative capacity, and vascular integrity. Neural stem cells (NSCs) and cerebral vasculature are both critica...
A novel gene edited rat model of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) [0.03%]
一种新颖的脑自身显性动脉病亚皮质梗死和白质脑病(CARASIL)基因编辑大鼠模型
Brittany Monte,Judianne Davis,Xiaoyue Zhu et al.
Brittany Monte et al.
Background: Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL) is a rare hereditary cerebral small vessel disease associated with loss-of-function mutations in the High T...
A study on the effectiveness of individual centered goal-oriented cognitive rehabilitation in vascular dementia [0.03%]
血管性痴呆个体化目标认知康复效果研究
Aayushi Srivastava,Ashwani Bhat,Vaibhav Agarwal
Aayushi Srivastava
Introduction: Dementia encompasses a range of neurological conditions that impair cognitive functions, with vascular dementia (VaD) being a prominent non-degenerative form, especially among older adults. VaD is primarily ...
Ana Davlasheridze,Lena Rafsten,David Krabbe et al.
Ana Davlasheridze et al.
Objective: We aimed to summarize current evidence on social cognitive function in stroke survivors by: identifying social cognition domains assessed; describing assessment tools; reporting impairment prevalence; and outli...
Cerebral small vessel disease lesion segmentation methods: A systematic review [0.03%]
小脑血管病变分割方法：系统性综述
Jolene Phelps,Manpreet Singh,Cheryl R McCreary et al.
Jolene Phelps et al.
Cerebral small vessel disease (CSVD) can manifest as brain lesions visible on magnetic resonance imaging, including white matter hyperintensities (WMH), cerebral microbleeds (CMB), perivascular spaces (PVS), lacunes, and recent small subcor...
On the origin of cerebral small vessel disease: MRI markers of cSVD in young adults with hypertension [0.03%]
青年高血压患者脑小血管病影像学标志的研究
M H Snijders,E Janssen,E Verburgt et al.
M H Snijders et al.
Introduction: Cerebral small vessel disease (cSVD) contributes to stroke and cognitive decline, with MRI markers of cSVD increasing with age. Hypertension is an important risk factor for cSVD in older adults but its impac...
Disentangling the contributions of cerebrovascular-related white matter integrity markers to cognitive aging [0.03%]
脑血管相关白质完整性标志物对认知衰老的贡献分离
Elmira Agah,Sarah T Farias,David K Johnson et al.
Elmira Agah et al.
Objective: To determine the independent and joint associations of five markers of white matter integrity, including white matter hyperintensities (WMH), extracellular free water (FW), fractional anisotropy (FA), peak widt...
Comment on "Post-stroke cognitive impairment and fatigue in patients with white matter hyperintensities: A prospective cohort study" [0.03%]
关于“白质高负荷患者的卒中后认知障碍和疲劳：一项前瞻性队列研究”的评论
Rachana Mehta,Ranjana Sah
Rachana Mehta
•SDMT drop at baseline linked to higher Fazekas (WMH) scores.•No follow-up MoCA/SDMT association after multiple correction.•Practice effects likely inflated cognitive test recovery scores.•High attrition biased against fatigue and cogni...