Air pollution in relation to brain health indicators and global cognitive functioning in people with cardiovascular disorders along the heart-brain axis [0.03%]
心血管疾病患者的心脑轴空气污染暴露与大脑健康指标和全球认知功能之间的关系研究
Erik J Timmermans,Esther E Bron,Michiel L Bots et al.
Erik J Timmermans et al.
There is increasing evidence of an inverse relationship between air pollution and cognitive functioning. Yet, the biological mechanisms underlying this relationship remain underexplored in healthy and vulnerable populations. This study exam...
Defining patient-reported outcomes and priorities for clinical trials in CADASIL through an international survey [0.03%]
通过国际调查定义CADASIL临床试验的患者报告结果和优先项
Nikolaos Karvelas,Sheila Connor,Andria Burroso et al.
Nikolaos Karvelas et al.
Background: A major challenge faced by clinical trials for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the heterogeneity of symptoms and variable progression pac...
Structural and vascular alterations of deep cervical lymph nodes in amyloid PET-positive Alzheimer's disease patients [0.03%]
淀粉样PET阳性阿尔茨海默病患者深颈部淋巴结的结构和血管改变
Tae Hyung Kim,Jin Geun Kwon,Jimmy Sung-Chuan Chao et al.
Tae Hyung Kim et al.
Background: Impaired clearance of brain-derived waste via the glymphatic-lymphatic system has been implicated in Alzheimer's disease (AD) pathogenesis. Although animal studies highlight the role of deep cervical lymph nod...
Evaluation of cerebrovascular reactivity impairment using resting-state BOLD MRI in symptomatic patients with unilateral intracranial artery occlusion [0.03%]
基于静息态BOLD信号评价单侧颅内动脉闭塞症状患者的脑血管反应性损伤
Yi Shan,Ya-Yan Yin,Bi-Xiao Cui et al.
Yi Shan et al.
Objectives: Cerebral vascular reactivity (CVR) is an independent predictor of poor prognosis for patients with symptomatic middle cerebral artery (MCA)/internal carotid artery (ICA) occlusion. This study assessed CVR impa...
Intracranial arterial calcification and cerebrovascular function in the general aging population - A 7T MRI Study [0.03%]
颅内动脉钙化与一般老龄化人群的脑血管功能的关系——一项7T磁共振成像研究
Anna M Streiber,Carmen Kuenen,Stanley D T Pham et al.
Anna M Streiber et al.
Background: Intracranial arteriosclerosis may impair downstream cerebrovascular function, but the underlying mechanisms remain unclear. Using 7T MRI, we investigate the association between intracranial arteriosclerosis an...
Editorial for cerebral circulation cognition & behavior special issue on brain health [0.03%]
认知与行为脑健康专刊主编述评
Philip B Gorelick,Anders Wallin
Philip B Gorelick
Gadolinium- and water-based blood-brain barrier dysfunction measures in patients with sporadic small vessel disease [0.03%]
特发性小血管疾病的血脑屏障功能紊乱的 gadolinium 和水分测量方法
Michael S Stringer,Xingfeng Shao,Hedok Lee et al.
Michael S Stringer et al.
Background: Subtle blood-brain barrier (BBB) leakage has been detected in small vessel disease (SVD). While established methods rely on gadolinium-based contrast agents (GBCA), diffusion-weighted arterial spin labelling (...
Deep learning retinal imaging model identifies poor brain health among older adults without dementia [0.03%]
深度学习视网膜成像模型识别无痴呆老年人的大脑健康问题
Bonnie Yin Ka Lam,An Ran Ran,Yuan Cai et al.
Bonnie Yin Ka Lam et al.
Introduction: The i-Cog Brain Health is a validated deep learning model for differentiating Alzheimer's disease dementia from cognitively unimpaired subjects based on retinal photographs. This study aimed to apply the i-C...
The need for post-stroke cognitive screening - the rationale behind the Hungarian adaptation of the Oxford Cognitive Screen (OCS) and its pilot study [0.03%]
卒中后的认知筛查的需求-牛津认知屏幕（OCS）匈牙利版本的合理应用及其试点研究的原因
Tímea Tünde Takács,Judit Kárpáti,Edina Szabó et al.
Tímea Tünde Takács et al.
Background: Post-stroke cognitive impairment (PSCI) is a frequent yet underdiagnosed consequence of stroke, with significant implications for quality of life, functional outcomes and long-term prognosis. Despite its impor...
The international society of vascular behavioural and cognitive disorders: highlights from VasCog 2025 in the UK [0.03%]
国际血管性行为和认知障碍学会：英国VasCog 2025会议亮点
Anna Marseglia,Roxana O Carare,Jessica L Teeling et al.
Anna Marseglia et al.
•AI-driven tools and multimodal biomarkers emerged as key for early VCID detection.•Novel neuroimaging, fluid, and retinal markers show promise for precision diagnostics.•BBB leakage and inflammation could early drive small vessel diseas...