Imaging markers of vascular cognitive impairment: Current advances and future directions [0.03%]
血管性认知障碍的影像标志物:当前进展与未来方向
Marco Duering,Prashanthi Vemuri
Marco Duering
Editorial commentary: The usefulness of the new VasCog-2-WSO criteria for the diagnosis of vascular cognitive impairment and dementia [0.03%]
述评:新VasCog-2-WSO血管性认知障碍和痴呆诊断标准的利弊分析
Perminder S Sachdev,Adam C Bentvelzen
Perminder S Sachdev
Cerebrovascular disease has a major role in the development of dementia, contributing to cognitive and functional decline in up to 75 % of all cases, and being the predominant or only cause in 15 to 20 % of cases. The importance of preventi...
Age-inappropriate white matter injury reveals hidden cerebral small vessel disease burden and mortality risk [0.03%]
年龄不适当的白质损伤揭示了隐藏的脑小血管疾病负担和死亡风险
Pei-Lin Lee,Wen-Yu Ou Yang,Kun-Hsien Chou et al.
Pei-Lin Lee et al.
Objective: White matter hyperintensities (WMH) are a core marker of cerebral small vessel disease (CSVD), but their interpretation is limited by strong age-dependence. We hypothesized that WMH burden disproportionate to a...
Jessica Lebenberg,Louis Lambert,Laura Tintoré-Carbonell et al.
Jessica Lebenberg et al.
Background & aims: Cerebral microbleeds (CMBs) are observed in one-third of CADASIL patients and increase with age. Factors associated with CMBs vary across studies, likely due to inadequate handling of their zero-inflate...
Reply to: "Node-level inference and score construction may overstate the diagnostic utility of cervical lymph node ultrasound in Alzheimer's disease" [0.03%]
关于“脑淀粉样变性血管病相关颈部淋巴结超声诊断价值的商榷”的回应
Tae Hyung Kim,Jin Geun Kwon,Jimmy Sung-Chuan Chao et al.
Tae Hyung Kim et al.
•GEE sensitivity analyses retained the principal categorical findings.•Continuous nodal measurements remained non-significant after GEE adjustment.•Nested score structure reflects a phenotypic gradient, not independent signals.•AUC of s...
Node-level inference and score construction may overstate the diagnostic utility of cervical lymph node ultrasound in Alzheimer's disease [0.03%]
阿尔茨海默病患者的颈淋巴结超声诊断价值可能被高估了
Yaohui Liu
Yaohui Liu
None. Keywords: Alzheimer's disease; Cervical lymph node ultrasound; Clustered data analysis; Diagnostic mod...
Sex differences in documented clinical features of memory clinic patients: a natural language processing study [0.03%]
基于自然语言处理的记忆门诊患者临床特点性别差异研究
Sanne Kuipers,L Malin Overmars,Bram van Es et al.
Sanne Kuipers et al.
Introduction: Sex differences in signs and symptoms of cognitive impairment are well described in research cohorts, but whether they are reflected in routine clinical documentation is unknown. ...
Recognizing, managing, and preventing cognitive sequelae after stroke. A narrative review [0.03%]
卒中后的认知后遗症的识别、管理和预防:综述文章
Leonardo Pantoni,Slaven Pikija,Tuyen Van Nguyen et al.
Leonardo Pantoni et al.
Post-stroke cognitive impairment (PSCI) affects up to one-third of stroke survivors and is a major contributor to long-term disability and reduced quality of life. Its heterogeneous phenotype reflects the interplay of acute cerebrovascular ...
Arterial spin labeling MRI in CADASIL: Implications for cerebral small vessel disease and therapeutic trials [0.03%]
无创性动脉自旋标记血管造影技术对CADASIL脑小血管病的诊断价值及治疗意义
Masafumi Ihara,Satoshi Saito,Satoru Fujiwara et al.
Masafumi Ihara et al.
Cerebral small vessel disease (CSVD) is a major cause of lacunar stroke, vascular cognitive impairment, and gait disturbance, yet the development of disease-modifying therapies is limited by the lack of robust, non-invasive biomarkers of mi...
Response on the commentary on "Relevance of cerebral microbleeds with leaky blood brain barrier in traumatic brain injury and protective role of interferon-gamma: a cohort study" [0.03%]
关于“脑微出血与血脑屏障通透性在创伤性脑损伤中的相关性及干扰素γ的保护作用:一项队列研究”的评述回复
Xuan Vinh To,Fatima Nasrallah
Xuan Vinh To
•Partial-volume effects impact DCE-MRI and other modalities.•Tractography and structural connectivity (SC) are layers of modelling assumptions.•SC is model-dependent and requires validation against clinical outcomes.•Peripheral sampling...