Disentangling the contributions of cerebrovascular-related white matter integrity markers to cognitive aging [0.03%]
脑血管相关白质完整性标志物对认知衰老的贡献分离
Elmira Agah,Sarah T Farias,David K Johnson et al.
Elmira Agah et al.
Objective: To determine the independent and joint associations of five markers of white matter integrity, including white matter hyperintensities (WMH), extracellular free water (FW), fractional anisotropy (FA), peak widt...
Comment on "Post-stroke cognitive impairment and fatigue in patients with white matter hyperintensities: A prospective cohort study" [0.03%]
关于“白质高负荷患者的卒中后认知障碍和疲劳：一项前瞻性队列研究”的评论
Rachana Mehta,Ranjana Sah
Rachana Mehta
•SDMT drop at baseline linked to higher Fazekas (WMH) scores.•No follow-up MoCA/SDMT association after multiple correction.•Practice effects likely inflated cognitive test recovery scores.•High attrition biased against fatigue and cogni...
From dementia prevention research to global FINGER-based multi-domain interventions and implementation strategies [0.03%]
从痴呆症预防研究到基于FINGER的全球多领域干预及实施策略研究
Shireen Sindi,Manasa Shanta Näsholm,Mariagnese Barbera et al.
Shireen Sindi et al.
The demographic transition during the recent decades has resulted in an increase in older adults globally. Cognitive impairment and dementia are the leading causes of functional disability, which significantly decreases the quality of life ...
Technical and clinical validation of a novel deep learning-based white matter hyperintensity segmentation tool [0.03%]
一种基于深度学习的新的脑白质高信号分割工具的技术和临床验证研究
Benno Gesierich,Lukas Pirpamer,Dominik S Meier et al.
Benno Gesierich et al.
Introduction: White matter hyperintensities (WMH) on MRI are a hallmark of cerebral small vessel disease. Although numerous WMH segmentation tools exist, each presents relevant limitations that can impact their usability....
The effect of visit-to-visit blood pressure variability on cognitive function: state-of the-art [0.03%]
诊间血压变异性对认知功能的影响：最新研究进展
Michiaki Nagai,Isabel J Sible,Phillip J Tully et al.
Michiaki Nagai et al.
Visit-to-visit blood pressure (BP) variability (VVV) is a risk factor for cognitive impairment and cognitive decline, but several studies have recently shown that VVV also increases the risk of Alzheimer's disease (AD). Although the relatio...
Effect of carotid artery stenosis on cortical microinfarcts, white matter integrity, and brain volume: An interhemispheric comparison within the population-based Rotterdam Study [0.03%]
鹿特丹前瞻性人群队列研究中颅内动脉狭窄对皮质微梗死、白质和脑容量的影响：大脑半球间的比较
Frank J Wolters,Meike W Vernooij,Gennady V Roshchupkin et al.
Frank J Wolters et al.
Background: Carotid artery stenosis could contribute to gradual loss of brain function through chronic hypoxia and ischemia. Methods: W...
Burden and risk factors of Alzheimer's disease and other dementias in Vietnam from 1990 to 2021 - A comprehensive analysis from global burden disease [0.03%]
1990至2021年越南阿尔茨海默病和其他痴呆症的疾病负担及危险因素——全球疾病负担的全面分析
Quynh Phuong Vo,Bich Loan Dang,Bao Minh Ton Luu et al.
Quynh Phuong Vo et al.
Background: Alzheimer's disease (AD) is the primary cause of dementia worldwide, imposing a substantial health and economic burden. In Vietnam, an aging population and rapid socioeconomic changes have intensified concerns...
Statin treatment for cerebral small vessel disease: A systematic review and meta-analysis of randomized controlled trials [0.03%]
他汀类药物治疗脑小血管病的随机对照试验系统综述和荟萃分析
David Fresnais,Brynjar Fure
David Fresnais
Background: Cerebral small vessel disease (CSVD) is a chronic, progressive disorder that affects small blood vessels in the brain's white matter. This white matter damage appears on brain imaging as white matter hyperinte...
Post-stroke cognitive impairment and fatigue in patients with white matter hyperintensities. A prospective cohort study [0.03%]
白质高信号患者的卒中后认知障碍和疲劳：一项前瞻性队列研究
Joakim Ölmestig,Viktor Frederik Idin Sørensen,Ingrid Grimsgaard et al.
Joakim Ölmestig et al.
Background: Cognitive impairment, depression, and fatigue are often neglected symptoms post-stroke. This study aimed to identify how white matter hyperintensity (WMH), a marker for cerebral small vessel disease (CSVD), is...
Effect of liquiritin on the expression of BDNF, Bax, and Bcl-2 in the hippocampus of post-stroke depression rats [0.03%]
甘草素对抑郁模型大鼠海马BDNF、Bax和Bcl-2表达的影响
Gui-Liu Yan,Dan Dai,Qiang Zi et al.
Gui-Liu Yan et al.
Aims: The study intended to explore the therapeutic effect of liquiritin on PSD rats and its role in the pathogenesis of PSD. Methods: ...