The Acceptability of post-stroke cognitive testing through the lens of the theory of acceptability, a qualitative study [0.03%]
从可接受性理论的角度看卒中后认知测试的可接受性,一项定性研究
David McMahon,Diane Dixon,Terry Quinn et al.
David McMahon et al.
Background: Cognitive impairment is common after stroke and screening is recommended. However, there is a lack of evidence on the best way to assess cognition after stroke and a tendency to focus on the clinician rather t...
In search of a marker of altered cerebrovascular function in hypertension: Analysis of the fractional amplitude of low-frequency fluctuations in UK Biobank resting state fMRI data [0.03%]
在高血压中寻找脑血管功能改变的标志物:分析英国生物库静息状态功能性核磁共振成像数据中的低频波动幅度分数
Owen Bleddyn Woodward,Ian Driver,Emma Hart et al.
Owen Bleddyn Woodward et al.
The selfish brain mechanism proposes that in some patients with impaired cerebral blood flow (CBF) or cerebrovascular function, hypertension may develop as a compensatory mechanism that aims to maintain CBF by increasing systemic blood pres...
Small vessel disease burden and functional brain connectivity in mild cognitive impairment [0.03%]
轻度认知障碍的小血管疾病负担和功能脑连接性研究
Sofia Marcolini,Jaime D Mondragón,Esther E Bron et al.
Sofia Marcolini et al.
Background: The role of small vessel disease in the development of dementia is not yet completely understood. Functional brain connectivity has been shown to differ between individuals with and without cerebral small vess...
The relevance of the socio-emotional deficits in cerebral small vessels disease (CSVD): An exploratory study with sporadic CSVD and CADASIL patients [0.03%]
脑小血管疾病(CSVD)中社会情感缺陷的相关性:对散发性CSVD和CADASIL患者的探索研究
Ana Rita Silva,Irina Santos,Carolina Fernandes et al.
Ana Rita Silva et al.
Background: Cerebral Small Vessels Disease (CSVD) is categorized in different forms, the most common being the sporadic form and a genetic variant - Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and L...
Motoric cognitive risk syndrome trajectories and incident dementia over 10 years [0.03%]
十年内运动认知风险综合征轨迹与新发痴呆的关系
Donncha S Mullin,Danni Gadd,Tom C Russ et al.
Donncha S Mullin et al.
Background: Motoric Cognitive Risk (MCR) syndrome is a high-risk state for adverse health outcomes in older adults characterised by measured slow gait speed and self-reported cognitive complaints. The recent addition to t...
Metabolic syndrome and adiposity: Risk factors for decreased myelin in cognitively healthy adults [0.03%]
代谢综合症和脂肪过多:认知健康成人少髓鞘化的风险因素
Agnieszka Z Burzynska,Charles Anderson,David B Arciniegas et al.
Agnieszka Z Burzynska et al.
Metabolic syndrome (MetS) is a cluster of conditions that affects ∼25% of the global population, including excess adiposity, hyperglycemia, dyslipidemia, and elevated blood pressure. MetS is one of major risk factors not only for chronic d...
Measurement of resistance-area product by transcranial Doppler: An alternative tool for cognitive screening in hypertensive on drug treatment? [0.03%]
药物治疗高血压患者的阻力面积乘积经颅多普勒检测:一种认知筛查的替代工具吗?
Michel Ferreira Machado,Henrique Cotchi Simbo Muela,Valeria Aparecida Costa-Hong et al.
Michel Ferreira Machado et al.
Introduction: Arterial hypertrophy and remodeling are adaptive responses present in systemic arterial hypertension that can result in silent ischemia and neurodegeneration, compromising brain connections and cognitive per...
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia [0.03%]
多学科评论:针对血管因素导致痴呆的临床前研究
Sarmi Sri,Adam Greenstein,Alessandra Granata et al.
Sarmi Sri et al.
Although dementia research has been dominated by Alzheimer's disease (AD), most dementia in older people is now recognised to be due to mixed pathologies, usually combining vascular and AD brain pathology. Vascular cognitive impairment (VCI...
Testing the cognitive effects of tadalafil. Neuropsychological secondary outcomes from the PASTIS trial [0.03%]
他达拉非对认知影响的检验——PASTIS试验的神经心理学次要结果
Mathilde Mh Pauls,Jessica Fish,Lauren R Binnie et al.
Mathilde Mh Pauls et al.
Cerebral small vessel disease (SVD) is a major cause of cognitive impairment in older people. As secondary endpoints in a phase-2 randomised clinical trial, we tested the effects of single administration of a widely-used PDE5 inhibitor, tad...
The effects of CNS atrophy and ICVD on tests of executive function and functional status are mediated by intelligence [0.03%]
中枢神经系统萎缩和脑血管疾病对执行功能和功能状态检测的影响由智力介导
Donald R Royall,Raymond F Palmer
Donald R Royall
Background: Impairments in executive function (EF) are often attributed to ischemic cerebrovascular disease (ICVD) and frontal circuit pathology. However, EF can be distinguished from general intelligence and the latter i...