A systematic review of in vivo brain insulin resistance biomarkers in humans [0.03%]
人类在体脑胰岛素抵抗生物标志物的系统评价
Graham Reid,Brendan Sargent,Sarah Bauermeister et al.
Graham Reid et al.
Type 2 diabetes mellitus (T2DM) is associated with an elevated risk of dementia, prompting interest into the concept of brain-specific insulin resistance. However, the brain's reliance on insulin-independent glucose transporters complicates...
Associations of social and genetic background variables to neuro-cognitive biomarkers of psychosis [0.03%]
社会和遗传背景因素与精神病神经认知生物标志物的关系
Parker V Jarrett,Kiernan L O&#x;Mara,Audrey L Berardi et al.
Parker V Jarrett et al.
Socioeconomic (SES) and ethno-racial factors may tilt psychosis diagnoses for persons from different backgrounds. Clinical diagnoses depend on patient and informant reports and are suspected of being susceptible to unintended bias. Diagnose...
Dimensions of Psychosis in Delirious and Catatonic Trauma Critically Ill Patients [0.03%]
谵妄和类木僵性创伤重症患者的幻觉维度分析
Ming-Ray Xu,Trey W McGonigle,Jinyuan Liu et al.
Ming-Ray Xu et al.
Objective: We examined the effect of delirium and catatonia on psychosis symptom presentation in trauma intensive care unit (TICU) patients without previous history of serious psychiatric illness. ...
Factors Affecting the Willingness of African-American and American Indian/Alaska Native Communities to Engage in Genetic and Biomarker Research: The UBIGR Study [0.03%]
美国少数族裔社区参与遗传和生物标志物研究的意愿性：UBIGR研究的影响因素分析
Diane C Gooding,Fabu P Carter,Emre Umucu et al.
Diane C Gooding et al.
Background: Despite the disproportionate impact of Alzheimer's disease (AD) dementia on Black/African-American and American Indian/Alaska Native groups, they have been underrepresented in biomarker research. Research inve...
Electroretinographic dysfunction, insulin resistance, and childhood trauma in early-course psychosis: A case-control exploratory study [0.03%]
电眼图异常、胰岛素抵抗和童年创伤在病程早期的精神病中的相关性：一项病例对照探索性研究
Erik Velez-Perez,Nicolas Raymond,Chelsea Kiely et al.
Erik Velez-Perez et al.
Background: Electroretinographic dysfunction is observed in psychosis, with a-wave and b-wave amplitudes potentially serving as biomarkers. Insulin resistance (IR) and childhood trauma (CT) have also been associated with ...
Developing non-invasive molecular markers for early risk assessment of Alzheimer's disease [0.03%]
阿尔茨海默病早期风险评估的无创分子标记物研发
Tapas K Sur,Tanmoy Mondal,Zarish Noreen et al.
Tapas K Sur et al.
Alzheimer's disease (AD) is a heterogeneous neurodegenerative disease, with no standard biomarker(s) to detect or confirm its risk at an early stage. The prevalence of AD increases exponentially worldwide in people of ages over 65 and older...
Cognitive performance and differentiation of B-SNIP psychosis Biotypes: Algorithmic Diagnostics for Efficient Prescription of Treatments (ADEPT) - 2 [0.03%]
B-SNIP精神病亚型的认知表现和区分：用于有效开具治疗方案的算法诊断(ADEPT)-第2部分
Brett A Clementz,Ishanu Chattopadhyay,S Kristian Hill et al.
Brett A Clementz et al.
Objective: The B-SNIP consortium validated neurobiologically defined psychosis Biotypes (BT1, BT2, BT3) using cognitive and psychophysiological measures. B-SNIP's biomarker panel is not practical for most settings. Previo...
Walid Yassin,Kendra M Loedige,Cassandra M J Wannan et al.
Walid Yassin et al.
The past decade witnessed substantial discoveries related to the psychosis spectrum. Many of these discoveries resulted from pursuits of objective and quantifiable biomarkers in tandem with the application of analytical tools such as machin...
Multimodal prediction of the need of clozapine in treatment resistant schizophrenia; a pilot study in first-episode psychosis [0.03%]
针对难治性精神分裂症的氯氮平需求的多模态预测；首次发作精神病中的一个试点研究
Jonatan M Panula,Athanasios Gotsopoulos,Jussi Alho et al.
Jonatan M Panula et al.
As many as one third of the patients diagnosed with schizophrenia do not respond to first-line antipsychotic medication. This group may benefit from the atypical antipsychotic medication clozapine, but initiation of treatment is often delay...
Rui Liu,Ernest V Pedapati,Lauren M Schmitt et al.
Rui Liu et al.
Objective: Fragile X Syndrome (FXS) is the leading monogenic cause of intellectual disability and autism spectrum disorder. Currently, there are no established biomarkers for predicting and monitoring drug effects in FXS,...