Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles [0.03%]
致编辑信件：流行病学在验证长条状矿物颗粒毒理模型的有效性中起关键作用
Ann Wylie,Andrey Korchevskiy
Ann Wylie
The authors reply to the comments of Drs. Gualtieri and di Giuseppe on the short communication by Wylie and Korchevskiy - Carcinogenicity of fibrous glaucophane: how to fill data gaps? (2021 Current Research in Toxicology Volume 2, pp. 202-...
Lead exposure induces dysregulation of constitutive heterochromatin hallmarks in live cells [0.03%]
铅暴露可导致活细胞中组成型异染色质标志的失调
Oscar F Sánchez,Li F Lin,Junkai Xie et al.
Oscar F Sánchez et al.
Lead (Pb) is a heavy metal contaminant commonly found in air, soil, and drinking water due to legacy uses. Excretion of ingested Pb can result in extensive kidney damages due to elevated oxidative stress. Epigenetic alterations induced by e...
In silico study reveals binding potential of rotenone at multiple sites of pulmonary surfactant proteins: A matter of concern [0.03%]
基于计算的研究发现罗特宁与肺表面活性物质蛋白多个位点结合的可能性：值得关注的现象
Prem Rajak,Sumedha Roy,Achintya Kumar Pal et al.
Prem Rajak et al.
Rotenone is a broad-spectrum pesticide employed in various agricultural practices all over the world. Human beings are exposed to this chemical through oral, nasal, and dermal routes. Inhalation of rotenone exposes bio-molecular components ...
Teratogenicity and toxicity of the new BPA alternative TMBPF, and BPA, BPS, and BPAF in chick embryonic development [0.03%]
新型BPA替代品TMBPF以及BPA、BPS和BPAF对鸡胚发育致畸性和毒性的研究
Kristen G Harnett,Lucy G Moore,Ashley Chin et al.
Kristen G Harnett et al.
Bisphenol A (BPA) is a widely known, yet controversial reproductive toxin, capable of inducing reproductive, developmental, and somatic growth defects across species. Due to scientific findings and public concern, companies have developed B...
The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove [0.03%]
新的精神活性物质25H-NBOMe和25H-NBOH诱导斑马鱼胚胎异常发育，并相互作用在DNA的主要缝隙中
Wellington Alves de Barros,Camila da Silva Nunes,Juliana Alves da Costa Ribeiro Souza et al.
Wellington Alves de Barros et al.
Toxicological effects of 25H-NBOMe and 25H-NBOH recreational drugs on zebrafish embryos and larvae at the end of 96 h exposure period were demonstrated. 25H-NBOH and 25H-NBOMe caused high embryo mortality at 80 and 100 µg mL-1, respectivel...
Combination of ebselen and hydrocortisone substantially reduces nitrogen mustard-induced cutaneous injury [0.03%]
Ebselen和氢化可的松联合使用能大幅减少氮芥引起的皮肤损伤
Hemanta C Rao Tumu,Benedette J Cuffari,Blase Billack
Hemanta C Rao Tumu
The purpose of the present study was to investigate the vesicant countermeasure effects of hydrocortisone (HC) and ebselen (EB-1), administered as monotherapy or as a combination treatment. The mouse ear vesicant model (MEVM) was utilized a...
Risperidone induced alterations in feeding and locomotion behavior of Caenorhabditis elegans [0.03%]
利培酮对秀丽隐杆线虫的进食和运动行为的影响
Aaditya Vikram Gaur,Rakhi Agarwal
Aaditya Vikram Gaur
Antipsychotic drugs (APDs) are prescribed for the treatment of psychiatric illness. However, these drugs can also contribute to several developmental and behavioral disorders. Contemporary studies to evaluate the toxic effects of numerous a...
Erratum to "Using yeast two-hybrid system and molecular dynamics simulation to detect venom protein-protein interactions" [Curr. Res. Toxicol. 2 (2021) 1-7] [0.03%]
《使用酵母双杂交系统和分子动力学模拟检测毒液蛋白质相互作用》[Curr. Res. Toxicol. 2 (2021) 1-7]的勘误表
Ying Jia,Paulina Kowalski,Ivan Lopez
Ying Jia
[This corrects the article DOI: 10.1016/j.crtox.2021.02.006.]. © 2021 The Author(s).
Published Erratum
Current research in toxicology. 2021 Oct 29:2:366. DOI:10.1016/j.crtox.2021.10.001 2021
In silico prediction of nuclear receptor binding to polychlorinated dibenzofurans and its implication on endocrine disruption in humans and wildlife [0.03%]
核受体对多氯二苯并呋喃结合的计算机辅助预测及其对人体和野生动物内分泌干扰的影响
Lukman K Akinola,Adamu Uzairu,Gideon A Shallangwa et al.
Lukman K Akinola et al.
Polychlorinated dibenzofurans (PCDFs) are known to cause endocrine disruption in humans and wildlife but the mechanisms underlying this disruption have not been adequately investigated. In this paper, the susceptibility of the endocrine sys...
Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats [0.03%]
急性二异丙基氟磷酸酯(DFP)对幼年Sprague-Dawley大鼠的急性和慢性神经毒性作用的性别差异
Eduardo A González,Jonas J Calsbeek,Yi-Hua Tsai et al.
Eduardo A González et al.
Preclinical efforts to improve medical countermeasures against organophosphate (OP) chemical threat agents have largely focused on adult male models. However, age and sex have been shown to influence the neurotoxicity of repeated low-level ...