Dual JAK and ROCK inhibition and comorbidities in rheumatoid arthritis [0.03%]
风湿性关节炎的双重JAK和ROCK抑制及并发症
Fabiola Atzeni,James Galloway
Fabiola Atzeni
Dual JAK and ROCK inhibition with CPL'116 in patients with rheumatoid arthritis with inadequate response to methotrexate: a randomised, double-blind, placebo-controlled, phase 2 trial [0.03%]
一项随机、双盲、安慰剂对照的Ⅱ期临床试验：CPL'116治疗甲氨蝶呤疗效不足的类风湿关节炎患者效果研究——该药同时抑制JAK和ROCK
Maciej Wieczorek,Bartłomiej Kisiel,Dorota Włodarczyk et al.
Maciej Wieczorek et al.
Background: Janus kinase (JAK) inhibitors are an effective treatment option in rheumatoid arthritis and other autoimmune diseases. However, the use of JAK inhibitors is associated with increased total cholesterol, LDL cho...
Exposure to hydroxychloroquine in early pregnancy and incidence of pre-eclampsia and pre-term delivery in patients with systemic lupus erythematosus in Sweden: a nationwide population-based cohort study [0.03%]
瑞典系统性红斑狼疮患者早期妊娠期间接触羟氯喹与子痫前期和早产发病率的关系：全国基于人群的队列研究
Ngoc V Nguyen,Anna Sandström,Elisabet Svenungsson et al.
Ngoc V Nguyen et al.
Background: Pregnant women with systemic lupus erythematosus (SLE) have elevated risks of pre-eclampsia and pre-term delivery. Hydroxychloroquine, the mainstay treatment during pregnancy in women with SLE, is currently a ...
Hydroxychloroquine use in pregnant women with systemic lupus erythematosus: the pill that shields [0.03%]
羟氯喹在系统性红斑狼疮孕产妇中的使用——保护孕妇的药物
Grégoire Martin de Frémont,Gaëlle Guettrot-Imbert,Nathalie Costedoat-Chalumeau
Grégoire Martin de Frémont
Whole-body MRI in patients with arthralgia or inflammatory arthritis after exposure to immune checkpoint inhibitors: a single-centre prospective imaging study [0.03%]
免疫检查点抑制剂后关节痛或炎性关节病患者的全身MRI影像研究
Kate Harnden,Navkiran Sidhu,Emma Rowbotham et al.
Kate Harnden et al.
Background: Musculoskeletal adverse events due to immune checkpoint inhibitors are common and can present clinically as inflammatory arthritis, polymyalgia rheumatica, or arthralgia. The pathoanatomy of musculoskeletal ad...
Occupational therapist-led versus rheumatologist-led care in people with hand osteoarthritis in Norway: an open-label, multicentre, randomised controlled, non-inferiority trial [0.03%]
挪威 occupational therapist指导与风湿病专家指导的护理在手骨关节炎患者中的效果：一种开放性、多中心、随机对照非劣效性试验
Annikka Polster,Unni Olsen,Lars Asphaug et al.
Annikka Polster et al.
Background: Hand osteoarthritis is a common musculoskeletal disease with a rising prevalence due to increased life expectancy. Because the disease is diagnosed on the basis of clinical examination and the first choice of ...
What can imaging teach us about immune checkpoint inhibitor-induced arthritis? [0.03%]
影像学如何帮助认识免疫检查点抑制剂诱导的关节炎？
Alice Tison,Anne R Bass
Alice Tison
Trends in the prevalence of autoimmune diseases during pregnancy in the UK, 2000-21: a retrospective cohort study [0.03%]
2000-2021年英国孕期自身免疫性疾病患病率的流行趋势：基于回顾性队列研究的结果
Megha Singh,Katherine Phillips,Jingya Wang et al.
Megha Singh et al.
Background: Autoimmune diseases are increasingly prevalent worldwide and disproportionately affect women of reproductive age, including during pregnancy. Given the association between autoimmune diseases, comorbidities, a...
Hilary K Brown,Natalie V Scime
Hilary K Brown