Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial [0.03%]
基于风险分层的普通骨科疼痛初级护理(STarT MSK) :集群随机对照试验
Jonathan C Hill,Stefannie Garvin,Kieran Bromley et al.
Jonathan C Hill et al.
Background: Risk-based stratified care shows clinical effectiveness and cost-effectiveness versus usual primary care for non-specific low back pain but is untested for other common musculoskeletal disorders. We aimed to t...
Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study [0.03%]
探究来自顺性别者及跨性别者健康个体和自身免疫炎症疾病患者的性差异T调节细胞:一项横断面研究
George A Robinson,Junjie Peng,Hannah Peckham et al.
George A Robinson et al.
Background: Sexual dimorphisms, which vary depending on age group and pubertal status, have been described across both the innate and adaptive immune system. We explored the influence of sex hormones on immune phenotype i...
The impact of COVID-19 on care of early inflammatory arthritis in the UK [0.03%]
COVID-19对英国早期炎症性关节炎护理的影响
Elizabeth MacPhie,Laura C Coates
Elizabeth MacPhie
Hormone replacement therapy (conjugated oestrogens plus bazedoxifene) for post-menopausal women with symptomatic hand osteoarthritis: primary report from the HOPE-e randomised, placebo-controlled, feasibility study [0.03%]
绝经后妇女的手部骨关节炎的激素替代治疗(结合雌激素加巴多昔芬):HOPE-e随机、安慰剂对照、可行性研究的主要报告
Jennifer A E Williams,Mae Chester-Jones,Catherine Minns Lowe et al.
Jennifer A E Williams et al.
Background: Symptomatic hand osteoarthritis is more common in women than in men, and its incidence increases around the age of menopause, implicating oestrogen deficiency. No randomised controlled trials of hormone replac...
Withholding methotrexate after vaccination with ChAdOx1 nCov19 in patients with rheumatoid or psoriatic arthritis in India (MIVAC I and II): results of two, parallel, assessor-masked, randomised controlled trials [0.03%]
印度RA和PsA患者接种ChAdOx1 nCoV-19疫苗后停用甲氨蝶呤的疗效和安全性研究(MIVACⅠ与Ⅱ):两项并行、评价者设盲、随机对照试验的结果
Teny Grace Skaria,Anu Sreeprakash,Rashwith Umesh et al.
Teny Grace Skaria et al.
Background: There is a necessity for an optimal COVID-19 vaccination strategy for vulnerable population groups, including people with autoimmune inflammatory arthritis on immunosuppressants such as methotrexate, which inh...
Research priorities to reduce the impact of musculoskeletal disorders: a priority setting exercise with the child health and nutrition research initiative method [0.03%]
减少肌肉骨骼疾病影响的研究重点:采用儿童健康和营养研究计划方法进行优先次序设置研究
Zoe Paskins,Clare E Farmer,Fay Manning et al.
Zoe Paskins et al.
Involving research users in setting priorities for research is essential to ensure the outcomes are patient-centred and maximise its value and impact. The Musculoskeletal Disorders Research Advisory Group Versus Arthritis led a research pri...
Mirella Fonti,Theresa Mader,Jan Burmester-Kiang et al.
Mirella Fonti et al.
Leonard H Calabrese,Cassandra M Calabrese
Leonard H Calabrese
Prediction models for the risk of total knee replacement: development and validation using data from multicentre cohort studies [0.03%]
基于多中心队列研究数据的全膝关节置换风险预测模型的建立和验证
Qiang Liu,Hongling Chu,Michael P LaValley et al.
Qiang Liu et al.
Background: Few prognostic prediction models for total knee replacement are available, and the role of radiographic findings in predicting its use remains unclear. We aimed to develop and validate predictive models for to...