The use of chemogenetic actuator ligands in nonhuman primate DREADDs-fMRI [0.03%]
非人灵长类动物DREADDs-fMRI中化学遗传学执行器配体的使用
Adriana K Cushnie,Daniel N Bullock,Ana M G Manea et al.
Adriana K Cushnie et al.
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are engineered receptors that allow for genetically targeted, reversible manipulation of cellular activity via systemic drug administration. DREADD induced manipulations a...
Degeneration of retina-brain components and connections in glaucoma: Disease causation and treatment options for eyesight preservation [0.03%]
青光眼中的视网膜-大脑成分及连接的退化：病因及其保护视力的治疗方案
Najam A Sharif
Najam A Sharif
Eyesight is the most important of our sensory systems for optimal daily activities and overall survival. Patients who experience visual impairment due to elevated intraocular pressure (IOP) are often those afflicted with primary open-angle ...
Commentary on Unnecessary reliance on multilevel modelling to analyse nested data in neuroscience: When a traditional summary-statistics approach suffices [0.03%]
对神经科学中不必要的多层模型分析嵌套数据的评论：传统汇总统计方法就足够了
Paul Alexander Bloom,Monica Kim Ngan Thieu,Niall Bolger
Paul Alexander Bloom
Unraveling the links between neurodegeneration and Epstein-Barr virus-mediated cell cycle dysregulation [0.03%]
解开神经退行性疾病和EB病毒介导的细胞周期失调之间的联系
Deeksha Tiwari,Nitish Mittal,Hem Chandra Jha
Deeksha Tiwari
The Epstein-Barr virus is a well-known cell cycle modulator. To establish successful infection in the host, EBV alters the cell cycle at multiple steps via antigens such as EBNAs, LMPs, and certain other EBV-encoded transcripts. Interesting...
Potential role of IGF-1/GLP-1 signaling activation in intracerebral hemorrhage [0.03%]
IGF-1/GLP-1信号激活在脑出血中的潜在作用
Ehraz Mehmood Siddiqui,Sidharth Mehan,Sonalika Bhalla et al.
Ehraz Mehmood Siddiqui et al.
IGF-1 and GLP-1 receptors are essential in all tissues, facilitating defense by upregulating anabolic processes. They are abundantly distributed throughout the central nervous system, promoting neuronal proliferation, survival, and differen...
The complex relationship between gut microbiota dysregulation and mood disorders: A narrative review [0.03%]
肠道微生物群失调与情绪障碍之间的复杂关系：叙事综述
Agnese Minuti,Francesca Brufani,Giulia Menculini et al.
Agnese Minuti et al.
Gut microbiota regulates neurotransmission, neurogenesis, neuroinflammation, and neuroendocrine signaling. The aim of the present review is to analyze the literature concerning gut microbiota dysregulation and mood symptoms, with the specif...
BioSimia, France CNRS network for nonhuman primate biomedical research in infectiology, immunology, and neuroscience [0.03%]
BioSimia，法国CNRS网络用于非人灵长类的生物医学研究在感染学，免疫学和神经科学方面的应用
Emmanuel Procyk,Martine Meunier
Emmanuel Procyk
Research and developments based on nonhuman primate models have a specific place in biomedical sciences, and nonhuman primate species also have a specific place in the public opinion on the use of animal in research. While nonhuman primates...
Diego Candia-Rivera
Diego Candia-Rivera
Recent experimental evidence on patients with disorders of consciousness revealed that observing brain-heart interactions helps to detect residual consciousness, even in patients with absence of behavioral signs of consciousness. Those find...
A little goes a long way: Neurobiological effects of low intensity rTMS and implications for mechanisms of rTMS [0.03%]
一点就通：低强度重复经颅磁刺激的神经生物学效应及其对重复经颅磁刺激机制的意义
Jessica Moretti,Jennifer Rodger
Jessica Moretti
Repetitive transcranial magnetic stimulation (rTMS) is a widespread technique in neuroscience and medicine, however its mechanisms are not well known. In this review, we consider intensity as a key therapeutic parameter of rTMS, and review ...
Entorhinal-hippocampal interactions lead to globally coherent representations of space [0.03%]
海马区与内嗅皮层的相互作用导致了空间的全局连贯表达
Taiping Zeng,Bailu Si,Xiaoli Li
Taiping Zeng
The firing maps of grid cells in the entorhinal cortex are thought to provide an efficient metric system capable of supporting spatial inference in all environments. However, whether spatial representations of grid cells are determined by l...