Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias [0.03%]
顶树突整合理论为理解分裂型精神障碍的组织性异常和意识提供了神经基础
Steven M Silverstein,Timothy Zolnik,Matthew Larkum et al.
Steven M Silverstein et al.
Recent discoveries involving pyramidal neurons with two zones of input integration (apical and basal), the contextual information they provide, and the neural circuitry and neuromodulation systems in which they are embedded, can contribute ...
Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias [0.03%]
顶树突整合理论为理解分裂症的组织障碍及意识提供了神经基础
Steven M Silverstein,Timothy Zolnik,Matthew Larkum et al.
Steven M Silverstein et al.
Recent discoveries involving pyramidal neurons with two zones of input integration (apical and basal), the contextual information they provide, and the neural circuitry and neuromodulation systems in which they are embedded, can contribute ...
Sulforaphane enhances locomotor recovery after spinal cord injury through antioxidant, anti-inflammatory, and JAK/STAT-modulating mechanisms [0.03%]
萝卜硫素通过抗氧化、抗炎和调节JAK/STAT机制增强脊髓损伤后的运动功能恢复
Zainab Hameed Saeed,Widyan Gataa Weshel,Ali Hussein Lafta et al.
Zainab Hameed Saeed et al.
Spinal cord injury (SCI) leads to irreversible neurological deficits primarily through secondary injury mechanisms, including oxidative stress and glial dysfunction. Sulforaphane (SFN), a naturally occurring isothiocyanate, has shown antiox...
A clinical prediction rule for myotonia permanens associated with the SCN4A p.Gly1306Glu variant [0.03%]
SCN4A p.Gly1306Glu突变相关的肌强直性永久性临床预测模型
Daniela Regonesi Polanco,Carlos Jaque Almendras,Marcela Lagos Lucero et al.
Daniela Regonesi Polanco et al.
Introduction: Myotonia permanens (MP), a life-threatening condition, is prevalent in Chile, and is frequently associated with the SCN4A p.Gly1306Glu variant (exon 22), likely due to a founder effect in this population. Lo...
C Besosa,Y Qin,S N Burke et al.
C Besosa et al.
Theories of large-scale neural coordination frequently assign distinct cognitive functions to discrete, independent frequency bands of oscillatory activity. In the hippocampus, memory encoding and recall are attributed to specific non-overl...
Monkeys integrate facial expressions and direct gaze to modulate gaze-following behavior [0.03%]
猴子结合面部表情和凝视方向来调节目光跟随行为
Ian Chong,Peter Thier
Ian Chong
For humans, being looked at directly can boost our readiness to follow another's gaze, but can monkeys invite an observer to engage with them in the same way? We trained three rhesus macaques on a head gaze-following task in which the portr...
Achieving cell-type specific transduction with adeno-associated viral vectors in pigeons [0.03%]
利用腺相关病毒载体在鸽子中实现细胞类型特异性转导
John Michael Tuff,Kevin Haselhuhn,Tatjana Surdin et al.
John Michael Tuff et al.
Birds are valuable models for studying learning, cognition, song, and vision, yet tools for controlling and recording brain activity with millisecond precision remain underutilized in avian research. Advances in methods such as chemogenetic...
A tool for high-throughput quantification of sleep-wake transitions in data from noninvasive piezoelectric cage systems [0.03%]
一种量化非侵入式压电笼系统数据中睡眠-清醒转换的高通量工具
Grant S Mannino,Andrea Lugo,Sean M Murphy et al.
Grant S Mannino et al.
Quantifying sleep quality in rodent models is critical for understanding its impact on neurological health and disease. Piezoelectric cage systems enable rapid, noninvasive measurement of multiple sleep metrics for large sample sizes of rod...
A computational architecture incorporating shallow brain networks: integrating parallel cortical and subcortical processing [0.03%]
一种包含浅脑网络的计算架构：整合并行皮层和皮下处理
Kwangjun Lee,Lorenzo Baracco,Cyriel M A Pennartz et al.
Kwangjun Lee et al.
Artificial neural networks commonly have deep hierarchical structures that were originally inspired by the neuroanatomical evidence of cortico-cortical connectivity pattern found in the mammalian brain. Largely under-represented in those mo...
Exploration of circulating metabolites in infants with abusive head trauma [0.03%]
婴儿虐待性头部损伤的循环代谢物研究
Estelle Maret,Tatjana Sajic,Kim Wiskott et al.
Estelle Maret et al.
Abusive head trauma (AHT) is a severe form of traumatic brain injury (TBI) and causes significant brain lesions by vigorous shaking. It is the leading cause of mortality and morbidity in children under 2 years of age. If not fatal, AHT can ...