Maresin-2 inhibits inflammatory and neuropathic trigeminal pain and reduces neuronal activation in the trigeminal ganglion [0.03%]
maresin-2抑制三叉神经炎症性和神经病理性疼痛并减少三叉神经节神经元活化
Raphael Vieira Lopes,Darciane Favero Baggio,Camila Rodrigues Ferraz et al.
Raphael Vieira Lopes et al.
Pain is a common symptom associated with disorders involving the orofacial structures. Most acute orofacial painful conditions are easily recognized, but the pharmacological treatment may be limited by the adverse events of current availabl...
Chelsey C Damphousse,Jaclyn K Medeiros,Nicole E Micks et al.
Chelsey C Damphousse et al.
Type 2 diabetes mellitus has steadily increased in prevalence over the past five decades. Among the health risks associated with this disorder are cognitive decline and are increased risk of developing dementia. To further investigate the l...
Optogenetic stimulation of the primary visual cortex drives activity in the visual association cortex [0.03%]
初级视觉皮层的光遗传学刺激驱动视觉相关皮层的活动
Michael Ortiz-Rios,Beshoy Agayby,Fabien Balezeau et al.
Michael Ortiz-Rios et al.
Developing optogenetic methods for research in non-human primates (NHP) is important for translational neuroscience and for delineating brain function with unprecedented specificity. Here we assess, in macaque monkeys, the selectivity by wh...
Unilateral caudate inactivation increases motor impulsivity in rhesus monkeys [0.03%]
单侧尾状核失活可增加恒河猴的运动冲动性
Mark A G Eldridge,Maya C Smith,Scott Hunter Oppler et al.
Mark A G Eldridge et al.
Impulsivity, the tendency to react quickly and without consideration of consequences, is correlated with asymmetry in the volume of the caudate nucleus in human patients. In this study, we sought to determine whether the induction of functi...
Dynamic structural remodeling of the human visual system prompted by bilateral retinal gene therapy [0.03%]
双侧视网膜基因治疗引起的视觉系统动态结构重塑
Manzar Ashtari,Philip Cook,Mikhail Lipin et al.
Manzar Ashtari et al.
The impact of changes in visual input on neuronal circuitry is complex and much of our knowledge on human brain plasticity of the visual systems comes from animal studies. Reinstating vision in a group of patients with low vision through re...
A framework and resource for global collaboration in non-human primate neuroscience [0.03%]
非人灵长类神经科学全球合作的框架和资源
Renée Hartig,P Christiaan Klink,Zlata Polyakova et al.
Renée Hartig et al.
As science and technology evolve, there is an increasing need for promotion of international scientific exchange. Collaborations, while offering substantial opportunities for scientists and benefit to society, also present challenges for th...
Efficient viral expression of a chemogenetic receptor in the old-world monkey amygdala [0.03%]
高效地在旧大陆猴杏仁核中表达化学遗传受体病毒感染系统
Walter Lerchner,Kiana Dash,Deborah Rose et al.
Walter Lerchner et al.
Genetically encoded synthetic receptors, such as the chemogenetic and optogenetic proteins, are powerful tools for functional brain studies in animals. In the primate brain, with its comparatively large, intricate anatomical structures, it ...
Motion distractors perturb saccade programming later in time than static distractors [0.03%]
运动性分散刺激比静止性分散刺激更晚干扰扫视计划
Devin H Kehoe,Lukas Schießer,Hassaan Malik et al.
Devin H Kehoe et al.
The mechanism that reweights oculomotor vectors based on visual features is unclear. However, the latency of oculomotor visual activations gives insight into their antecedent featural processing. We compared the oculomotor processing time c...
Are musical activities associated with enhanced speech perception in noise in adults? A systematic review and meta-analysis [0.03%]
音乐活动与成人噪声环境中言语感知改善之间的关系：系统评价和meta分析
Elisabeth Maillard,Marilyne Joyal,Micah M Murray et al.
Elisabeth Maillard et al.
The ability to process speech in noise (SPiN) declines with age, with a detrimental impact on life quality. Music-making activities such as singing and playing a musical instrument have raised interest as potential prevention strategies for...
Gonzalo Forno,Manojkumar Saranathan,Jose Contador et al.
Gonzalo Forno et al.
Alzheimer's disease (AD) is the most common cause of dementia worldwide. Increasing evidence points to the thalamus as an important hub in the clinical symptomatology of the disease, with the 'limbic thalamus' been described as especially v...