Protective effects of Embelin in Benzo[α]pyrene induced cognitive and memory impairment in experimental model of mice [0.03%]
Embelin对苯并[a]芘致小鼠认知记忆损伤的保护作用研究
Akansh Goal,Khadga Raj,Shamsher Singh et al.
Akansh Goal et al.
Alzheimer's disease (AD) is a neurodegenerative disease that affects the neurons in the hippocampus, resulting in cognitive and memory impairment. The most prominent clinical characteristics of AD are the production of amyloid-beta (Aβ) pl...
Hearing loss in juvenile rats leads to excessive play fighting and hyperactivity, mild cognitive deficits and altered neuronal activity in the prefrontal cortex [0.03%]
幼年期听力损失可导致大鼠过度嬉戏和多动、轻度认知缺陷及前额叶神经元活动异常
Jonas Jelinek,Marie Johne,Mesbah Alam et al.
Jonas Jelinek et al.
Background: In children, hearing loss has been associated with hyperactivity, disturbed social interaction, and risk of cognitive disturbances. Mechanistic explanations of these relations sometimes involve language. To in...
Physiological features of parvalbumin-expressing GABAergic interneurons contributing to high-frequency oscillations in the cerebral cortex [0.03%]
表达副球蛋白的GABA能中间神经元在皮层高频振荡中的生理特征
Katarina D Milicevic,Brianna L Barbeau,Darko D Lovic et al.
Katarina D Milicevic et al.
Parvalbumin-expressing (PV+) inhibitory interneurons drive gamma oscillations (30-80 Hz), which underlie higher cognitive functions. In this review, we discuss two groups/aspects of fundamental properties of PV+ interneurons. In the first g...
Frontal P300 asymmetry and congruence judgment: Retroactive switching is impaired during school day mornings in female adolescents [0.03%]
青少年女性在校上午时段前瞻性切换能力受损：P300脑电波不对称性的证据
Gabriel E Byczynski,Amedeo D&#x;Angiulli
Gabriel E Byczynski
Investigating frontal EEG asymmetry as a possible biomarker of cognitive control abilities is especially important in ecological contexts such as school and work. We used a novel approach combining judgment performance and hemispheric front...
Unveiling the development of human voice perception: Neurobiological mechanisms and pathophysiology [0.03%]
揭开人类语音感知的发展：神经生物学机制与病理生理学
Emily E Harford,Lori L Holt,Taylor J Abel
Emily E Harford
The human voice is a critical stimulus for the auditory system that promotes social connection, informs the listener about identity and emotion, and acts as the carrier for spoken language. Research on voice processing in adults has informe...
Intranasal insulin attenuates hypoxia-ischemia-induced short-term sensorimotor behavioral disturbances, neuronal apoptosis, and brain damage in neonatal rats [0.03%]
鼻内注射胰岛素减轻缺氧缺血诱导的新生大鼠短期感觉运动行为障碍，神经元凋亡和脑损伤
Chirag P Talati,Jonathan W Lee,Silu Lu et al.
Chirag P Talati et al.
There is a significant need for additional therapy to improve outcomes for newborns with acute Hypoxic-ischemic (HI) encephalopathy (HIE). New evidence suggests that insulin could be neuroprotective. This study aimed to investigate whether ...
Mateo López Espejo,Stephen V David
Mateo López Espejo
Accurate sound perception can require integrating information over hundreds of milliseconds or even seconds. Spectro-temporal models of sound coding by single neurons in auditory cortex indicate that the majority of sound-evoked activity ca...
Astrocytes: Role in pathogenesis and effect of commonly misused drugs in the HIV infected brain [0.03%]
星形胶质细胞：在病原学中的作用以及HIV感染大脑中常用药物的副作用的影响
Jessalyn Pla-Tenorio,Angela M Roig,Paulina A García-Cesaní et al.
Jessalyn Pla-Tenorio et al.
The roles of astrocytes as reservoirs and producers of a subset of viral proteins in the HIV infected brain have been studied extensively as a key to understanding HIV-associated neurocognitive disorders (HAND). However, their comprehensive...
Arash Afraz
Arash Afraz
Optogenetics has been a promising and developing technology in systems neuroscience throughout the past decade. It has been difficult though to reliably establish the potential behavioral effects of optogenetic perturbation of the neural ac...
The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics [0.03%]
SARS-CoV-2刺突糖蛋白与单胺氧化酶B相互作用并损害线粒体能量代谢
Chantal A Pileggi,Gaganvir Parmar,Hussein Elkhatib et al.
Chantal A Pileggi et al.
SARS-CoV-2 infection is associated with both acute and post-acute neurological symptoms. Emerging evidence suggests that SARS-CoV-2 can alter mitochondrial metabolism, suggesting that changes in brain metabolism may contribute to the develo...