Cross-sectional associations of radiographic multiple joint osteoarthritis and symptoms, laboratory values and the gut microbiota: A multimodal study in humans and pet dogs [0.03%]
放射性多关节骨关节炎的横断面联合与症状、实验室检查值和肠道微生物：人类和宠物狗的多模式研究
Amanda E Nelson,Liubov Arbeeva,Kelly Johnson et al.
Amanda E Nelson et al.
Objective: To describe the frequency of multiple joint osteoarthritis (MJOA) and symptoms, and associations with fecal microbial diversity and composition, in cohorts of humans and dogs. ...
Artificial intelligence in osteoarthritis research: summary of the 2025 OARSI pre-congress workshop [0.03%]
骨关节炎研究中的人工智能：2025年OARSI大会前工作坊内容总结
Matthew S Harkey,Kerry E Costello,Bella Mehta et al.
Matthew S Harkey et al.
Objective: Artificial intelligence (AI) is transforming musculoskeletal research, offering new approaches to diagnosis, prognosis, and patient management in osteoarthritis (OA). However, implementation and ethical challen...
Organ-on-chip technologies: Novel tools with the potential to revolutionize osteoarthritis research and clinical development [0.03%]
芯片器官技术：有望重塑骨关节炎研究和临床开发的新型工具
Carlo Alberto Paggi
Carlo Alberto Paggi
Objective: To critically evaluate the evolution of in vitro models for osteoarthritis (OA) research, with a specific focus on organ-on-chip (OOC) technologies, and to discuss their potential to overcome the limitations of...
A proteomics investigation of primary human articular chondrocyte isolation [0.03%]
人源性关节软骨细胞分离的蛋白质组学研究
Abby Brumwell,Simran Raheja,William Cawley et al.
Abby Brumwell et al.
Objective: Human primary articular chondrocytes (hPACs) are routinely isolated from articular cartilage for pre-clinical OA research. Collagenase digest of tissue is an essential step, yet the impact of lengthy enzymatic ...
Development of an iPSC-based screening platform identifying enhancers of chondrogenesis [0.03%]
一种基于iPSC的软骨发生增强剂筛选平台的开发研究论文题目
Aisling O&#x;Brien,Maojia Xu,Enda O&#x;Connell et al.
Aisling O&#x;Brien et al.
Objective: There is currently no long-term treatment for the repair of damaged cartilage and osteoarthritis (OA). Induced pluripotent stem cells (iPSCs) are an ideal cell source for screening platforms due to their abilit...
The relationship between circulating and tissue biomarkers and OA-related pain: A systematic literature review [0.03%]
循环和组织生物标志物与骨关节炎相关疼痛的关系：系统文献回顾
Sylvain Mathieu,Liisa Kuhi,Marie Binvignat et al.
Sylvain Mathieu et al.
Objective: This study aimed to provide an overview of the relationship between osteoarthritis (OA) pain and various fluid biomarkers by conducting a systematic literature review (SLR), to help the development of OA-relate...
Biochemical biomarkers of knee osteoarthritis progression: Results from the FNIH biomarkers consortium progress OA study [0.03%]
美国FNIH关节炎生物标志物联盟计划进展期骨关节炎研究中膝骨关节炎进展的生化标志物
Jamie E Collins,Douglas Robinson,Nigel Arden et al.
Jamie E Collins et al.
Objective: The Foundation for National Institutes of Health (FNIH) OA Biomarkers Consortium aims to identify and qualify biomarkers to support drug development in knee osteoarthritis (OA). The PROGRESS OA study aims to ex...
Defining and measuring varus thrust in knee osteoarthritis: A scoping review of current evidence and challenges [0.03%]
膝骨关节炎内翻力的定义及测量：当前证据与挑战综述
Vincenzo E Di Bacco,Zaryan Masood,Joshua A J Keogh et al.
Vincenzo E Di Bacco et al.
Objective: This scoping review investigated the definitions, assessment methods, and current applications of varus thrust (VT) in knee osteoarthritis (OA). ...
Walking is the form of physical activity people with osteoarthritis in the hip or knee choose and maintain after two years [0.03%]
膝骨关节炎和髋骨关节炎患者两年内的步行锻炼行为分析
R Bendrik,M Peterson,K Bröms et al.
R Bendrik et al.
Objective: To evaluate which form and type of physical activity individuals with hip or knee osteoarthritis choose and maintain one and two years after an individualised intervention for physical activity and further to e...
Longitudinal associations between bilateral versus unilateral knee osteoarthritis and physical performance measures [0.03%]
双膝骨关节炎与单膝骨关节炎与体格检查指标纵向关联的对比研究
Jennifer S Hanberg,Faith Selzer,Elena Losina et al.
Jennifer S Hanberg et al.
Background: Bilateral knee osteoarthritis (KOA) is common, but evidence for the effect of bilateral versus unilateral KOA on functional outcomes is conflicting. We aimed to examine the association between bilateral versus...