Evaluating therapeutic efficacy of iopanoic acid in a DMM-induced osteoarthritis mouse model and osteochondral lesioned human explants [0.03%]
评估碘帕醇酸在DMM诱导的骨关节炎小鼠模型和人软骨组织切片中的治疗效果
S Sana Sayedipour,Giorgia Mazzini,Margo Tuerlings et al.
S Sana Sayedipour et al.
Objective: To evaluate the therapeutic potential of iopanoic acid (IOP), a thyroid hormone pathway inhibitor, in preserving cartilage and bone integrity in osteoarthritis (OA), using in vivo and ex vivo tissue models. ...
Does pain pattern matter? Association of intermittent, constant, predictable and unpredictable knee pain to patient-reported knee symptom acceptability in knee osteoarthritis [0.03%]
疼痛模式重要吗？膝骨关节炎患者间歇性、持续性、可预测性和不可预测性的膝痛与患者的症状可接受性之间的关系
Gillian A Hawker,Lisa Carlesso,Ian Stanaitis et al.
Gillian A Hawker et al.
Objective: People with knee osteoarthritis (OA) describe intermittent, constant, predictable, and unpredictable pain, but how different pain patterns affect symptom experience is unknown. ...
Assessment of degenerative states of articular cartilage via sparse laser-based mid-infrared attenuated total reflectance spectroscopy [0.03%]
基于稀疏激光的中红外衰减全反射光谱评估关节软骨退变状态
P Krebs,U Blazhko,M Nägele et al.
P Krebs et al.
Objective: To investigate capability of sparse mid-infrared spectral data obtained by a prototype infrared attenuated total reflection (IR-ATR) laser spectroscopic system to classify human cartilage degenerative state. ...
CT-based 3D bone shape modes are associated with clinically meaningful functional improvement after total knee arthroplasty [0.03%]
基于CT的三维骨形模与全膝关节置换术后临床意义的功能改善有关
Wei Wang,Lawrence Chun Man Lau,John A Lynch et al.
Wei Wang et al.
Objective: To evaluate whether preoperative CT-derived three-dimensional bone shape modes are associated with failure to achieve the Knee Society Score Function subscore (KSS-Function) minimal clinically important differe...
Degeneration dependent changes in human knee cartilage mechanical properties revealed by synchrotron tomography based finite element modeling [0.03%]
基于同步辐射层析成像的有限元模型揭示退变对人膝关节软骨力学性能的影响
Viktor Jönsson,Lorenzo Grassi,Anna Gustafsson et al.
Viktor Jönsson et al.
Objective: Knee osteoarthritis (OA) is a chronic joint disease associated with pain and reduced function. The mechanisms underlying OA and how mechanical properties change with the disease are not fully understood, partly...
Frailty is associated with lower-limb osteoarthritis incidence over six-years regardless of sex and type of frailty index in the Canadian longitudinal study on aging [0.03%]
脆弱性与加拿大老年人纵向研究中6年内下肢骨关节炎的发病率降低有关，无论性别和脆弱性指数类型如何
Carson Halliwell,Rebecca Moyer,Alexandra Legge et al.
Carson Halliwell et al.
Objective: We aimed to test whether increases in frailty are associated with a higher likelihood of developing lower-limb osteoarthritis over six-years, with stronger associations in females, and to compare whether result...
Who is waiting to see the surgeon? sociodemographic, clinical characteristics and previous osteoarthritis care of people with knee osteoarthritis referred to public hospitals in Victoria, Australia [0.03%]
等候看外科医生的人是谁？澳大利亚维多利亚州转诊到公立医院的膝关节骨性关节炎患者的社福述絥、临床特点及以往的骨性关节炎治療情况
Juanita Low,Danilo De Oliveira Silva,Allison M Ezzat et al.
Juanita Low et al.
Aim: To describe the sociodemographic, clinical characteristics, and previous care received by people with knee osteoarthritis awaiting orthopaedic assessment, and compare these factors between culturally and linguistical...
Small bone replacement leads to greater gait asymmetry, cartilage damage, and osteophyte formation than ligament injury in a porcine wrist model [0.03%]
小骨移植导致步态不对称、软骨损伤和骨刺形成比猪腕模型中的韧带损伤更严重
Quianna M Vaughan,Amy M Morton,Douglas C Moore et al.
Quianna M Vaughan et al.
Objective: This study evaluated the Yucatan minipig (YMP) as a translational large-animal model of wrist osteoarthritis (OA) following ligament injury (LI) or small bone replacement (SBR) in a 12-week in vivo study. ...
Archetypal analysis of pain measures in a diverse population-based cohort: Exploring cross-sectional relationships with outcomes [0.03%]
基于人群的多样化队列中疼痛测量的原型分析：与横断面结果的关系探索
Parsa Pazooki,Liubov Arbeeva,Simoni Tomar et al.
Parsa Pazooki et al.
Objective: Pain experiences are complex, multifactorial, and subjective. Pain phenotyping can provide a holistic view of pain experiences by identifying distinct pain profiles. This study aimed to characterize chronic pai...
Characterization of calcifications in posterior horn of human meniscus using micro-computed tomography [0.03%]
微焦平面CT在人类半月板后角钙化表征中的应用研究
Ville-Pauli Karjalainen,Iida Hellberg,Aleksandra Turkiewicz et al.
Ville-Pauli Karjalainen et al.
Objective: Meniscal calcifications are associated with meniscal degeneration and osteoarthritis (OA). We investigated micro-computed tomography (μCT) imaging for identification of calcification patterns caused by basic c...