Christian Anker-Hansen,Eric Manderstedt,Christina Lind-Halldén et al.
Christian Anker-Hansen et al.
Objective: Degenerative orthopedic diseases (DODs) such as osteoporosis, osteoarthritis, spondylosis, spinal stenosis, and disc herniation are common disorders. Both common and rare genetic risk factors may contribute to ...
Progression of bone and joint space deformity in patients with mild knee osteoarthritis: Data from the IMI-APPROACH cohort [0.03%]
H Chien Nguyen,Eva Bax,Roel J H Custers et al.
H Chien Nguyen et al.
Objective: This study aimed to divide leg malalignment into different categories of valgus and varus of the femur, tibia, and intra-articular knee joint and investigates whether knee osteoarthritis (OA) patients are susce...
KORT - Knee osteoarthrosis radiotherapy trial: Protocol for a multidisciplinary pathway and a planned sham-controlled phase III trial of low-dose radiotherapy in knee osteoarthritis [0.03%]
Jörg Andreas Müller,Jassem Alsalloum,Dirk Vordermark et al.
Jörg Andreas Müller et al.
Objective: Low-dose radiotherapy (LDRT) is widely used in German-speaking countries for painful degenerative and inflammatory musculoskeletal disorders, but recent sham-controlled trials using non-standard dose concepts r...
The impact of overall lumbar disc degeneration burden on disability outcomes following surgery for lumbar spinal stenosis due to osteoarthritis [0.03%]
Y Raja Rampersaud,J Denise Power,Celina Nahanni et al.
Y Raja Rampersaud et al.
Objective: Individuals with lumbar spinal stenosis due to osteoarthritis (LSS-OA) often have disc degeneration at multiple levels, as well as multiple symptomatic appendicular joints. These have received limited attention...
CSPG4+ extracellular vesicles carry fibronectin and interleukin-11 and reflect radiographic severity in knee osteoarthritis [0.03%]
Xin Zhang,Lindsey Adair MacFarlane,Janet L Huebner et al.
Xin Zhang et al.
Objectives: To evaluate chondroitin sulfate proteoglycan 4 (CSPG4)+ plasma extracellular vesicles (EVs) as a novel biomarker for knee osteoarthritis (OA) severity across independent study cohorts. ...
Dose-response effects of transcutaneous electrical nerve stimulation for knee osteoarthritis: A systematic review and meta-analysis [0.03%]
Simón Bueno-López,Jaime Jordán-López,Maria Dolores Arguisuelas et al.
Simón Bueno-López et al.
Objective: To clarify the analgesic efficacy of transcutaneous electrical nerve stimulation (TENS) in knee osteoarthritis (KOA) and examine whether stimulation parameters moderate treatment effects. ...
Increase in knee-adjacent subcutaneous fat is associated with cartilage degeneration independent of BMI: A four-year analysis of the OAI dataset [0.03%]
Gabby B Joseph,Charles E McCulloch,Felix Liu et al.
Gabby B Joseph et al.
Objective: To determine whether changes in knee-adjacent subcutaneous fat (kaSCF) are associated with changes in cartilage thickness, cartilage T2 relaxation times, pain, and radiographic Kellgren Lawrence (KL) grade over...
The impact of knee osteoarthritis on cardiovascular disease mortality: A systematic review and meta-analysis [0.03%]
Pei-En Kao,Po-Yuan Chen
Pei-En Kao
Objective: This study aimed to conduct a systematic review and meta-analysis to evaluate the risk of cardiovascular disease (CVD) mortality in patients with knee osteoarthritis (OA). ...
The common and specific osteoarthritis gait characteristics: A quantitative grading system for OA associated gait changes in mice [0.03%]
一种与小鼠骨关节炎相关的步态变化的定量分级系统
Yajun Liu,Ashley Knebel,Jing Ding et al.
Yajun Liu et al.
Objective: Osteoarthritis (OA) severity in animal models has been quantified primarily through grading systems reflecting the changes of joint morphology. There is a lack of a uniform grading system to quantify the change...
Weight loss and physical activity after total knee replacement: Study protocol for the Healthy Living randomized controlled trial [0.03%]
膝关节置换术后减肥和身体活动水平的改变：健康生活随机对照试验方案研究
Christine A Pellegrini,Sara Wilcox,Clare Kennerley et al.
Christine A Pellegrini et al.
Background: Most people who receive a total knee replacement (TKR) are physically inactive and meet criteria for overweight/obesity, putting them at increased risk of poor functional outcomes and chronic diseases. This pa...