Pamidronate is ineffective for inflammatory-like low back pain associated with Modic type 1 changes: A double-blind, randomised controlled trial [0.03%]
潘环索治疗与ModicⅠ型改变相关的炎性腰背痛的疗效观察：一项双盲随机对照试验
Martin Soubrier,Charlotte Lanhers,Bruno Pereira et al.
Martin Soubrier et al.
Objective: Modic type 1 (MC-1) vertebral endplate changes are associated with chronic low back pain (LBP) and often reflect an inflammatory process. Pamidronate has demonstrated analgesic effects in conditions involving b...
Comparison of the efficacy and safety of acetaminophen versus NSAIDs for the treatment of chronic pain in older adults with osteoarthritis of the hip and knee: Findings from the randomized, double-blind, parallel-group, non-inferiority RETHINK study [0.03%]
一项随机、双盲、平行组、非劣效性研究：对 acetaminophen与 NSAIDs治疗老年人髋部和膝关节骨关节炎慢性疼痛的有效性和安全性进行比较——来自RETHINK研究的结果
Makoto Endo,Tsutomu Kawano,Masami Tokunaga et al.
Makoto Endo et al.
Objective: This study aimed to evaluate the non-inferiority of acetaminophen compared with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of chronic osteoarthritis-related pain in older adults. ...
CD5L is a potential negative regulator of chondrocyte apoptosis in osteoarthritis [0.03%]
CD5L可能是骨关节炎软骨细胞凋亡的负调控因子
Benjamin Brigant,Kashif Rasheed,Carolina Gómez Ortega et al.
Benjamin Brigant et al.
Objectives: CD5 antigen-like (CD5L) protein is a scavenger receptor involved in inflammation control and enriched in the synovial fluid and membranes of osteoarthritis (OA) patients. Although increased CD5L levels have be...
Physiotherapists experiences with cognitive behavioural therapy for insomnia (CBT-I) training: Mixed methods study [0.03%]
综合方法研究：物理治疗师进行失眠认知行为疗法培训的体验
Michelle Wang,Jillian Eyles,Samantha Bunzli et al.
Michelle Wang et al.
Objective: Explore physiotherapists' experiences with Cognitive Behavioural Therapy for Insomnia (CBT-I) training to understand factors that may influence implementation and upscaling of CBT-I training for physiotherapist...
Deep learning-based effusion-synovitis volume measured on MRI is associated with osteoarthritis progression: A longitudinal analysis of data from the osteoarthritis initiative [0.03%]
基于深度学习的MRI滑膜炎积液体积测量与骨关节炎进展相关性：来自骨关节炎计划数据的纵向分析
Adrian A Marth,Felix Liu,Ethan Pan et al.
Adrian A Marth et al.
Objective: To investigate whether the 48-month change in effusion-synovitis volume (ΔESV) is associated with concurrent knee osteoarthritis progression, and to compare these associations with those of semiquantitative ch...
Development of a population-anchored Z-score for MRI-based knee osteoarthritis disease activity: Data from the Osteoarthritis Initiative [0.03%]
基于MRI的膝骨关节炎疾病活动度的群体锚定Z评分的开发：来自骨关节炎倡议的数据
Jonggyu Baek,Julieann C Patarini,Emily Kirillov et al.
Jonggyu Baek et al.
Objective: We previously developed a novel imaging biomarker, reflecting whole-knee bone marrow lesion and effusion-synovitis volumes, to measure disease activity. This study describes the process used to develop a z-scor...
The impact of knee positioning on joint space width change: Data from the Osteoarthritis Initiative [0.03%]
膝关节定位对关节间隙宽度变化的影响：来自骨关节炎计划的数据
J T Crawmer,R Tang,A E Nelson et al.
J T Crawmer et al.
Objective: Quantify the longitudinal effect of knee positioning on radiographic joint space width (JSW) in knee OA. Design: This longit...
Racial Differences in Utilization of and Factors Contributing to the Use of Knee Replacement Surgery as a Treatment for Severe Knee Osteoarthritis: A Scoping Review [0.03%]
种族差异和膝关节置换术治疗严重膝骨关节炎的因素：综述研究
Samuel D Good,Max Krall,Collin Brantner et al.
Samuel D Good et al.
Objective: Differences in utilization of total knee arthroplasty (TKA) for Black patients with severe knee osteoarthritis (OA) have been well described. Understanding the factors that contribute to these differences is im...
Arthroscopically and manually minced cartilage demonstrates lower cell viability and lower proteoglycan deposition compared to isolated chondrons and chondrocytes [0.03%]
与分离的软骨细胞相比，关节镜和手动研磨的软骨具有较低的细胞活力和较低的蛋白多糖沉积物
Dunja Scheepmaker,Christopher V Nagelli,Katherine L Lydon et al.
Dunja Scheepmaker et al.
Objective: Autologous minced cartilage offers a single-stage, low-cost alternative to cell therapies for treatment of chondral defects. It is often derived from debrided defects or loose bodies, then minced for reimplanta...
Frequency and factors associated with neuropathic pain in patients with knee osteoarthritis [0.03%]
膝骨关节炎患者神经病理性疼痛的患病率及影响因素
Fulgence Kaboré,Abdoul Aziz,Ismael Ayouba Tinni et al.
Fulgence Kaboré et al.
Objective: To determine the frequency and factors associated with neuropathic pain in patients with knee osteoarthritis seen during rheumatology consultations. ...