The construct validity and responsiveness of measures of the predictability of intermittent knee pain in knee osteoarthritis [0.03%]
膝骨关节炎间歇性膝痛预测量表的构建效度和反应度
Gillian A Hawker,Hayton Chui,Ian Stanaitis et al.
Gillian A Hawker et al.
Objective: The Intermittent and Constant Osteoarthritis Pain (ICOAP) questionnaire was developed to assess the osteoarthritis (OA) pain experience, but does not currently incorporate pain predictability, which people with...
Training load and pain response during progressive resistance training in patients with hip osteoarthritis in the PROHIP trial [0.03%]
PROHIP试验中髋关节骨关节炎患者进行渐进性抗阻训练时的负荷与疼痛反应
Emma Smed Bryld,Laura Christiansen,Kim Gordon Ingwersen et al.
Emma Smed Bryld et al.
Objective: To describe training load and repetitions, illustrate the pre- and post-exercise hip pain intensity trajectories throughout a 12-week progressive resistance training (PRT) program, and evaluate the difference i...
Exploring the relationship between allostatic load and osteoarthritis: A cross-sectional analysis from the North West Adelaide Health Study [0.03%]
横断面分析：西北阿德莱德卫生研究中allostatic负荷与骨关节炎的关系探索
Sarah N Schwetlik,Katherine L Baldock,Catherine L Hill et al.
Sarah N Schwetlik et al.
Objective: Cumulative stress-response system dysregulation, known as allostatic load (AL), is suggested as a possible mechanism that may connect upstream health determinants with OA. Our objective was to evaluate the cros...
Peripheral blood DNA methylation changes are predictive of incident radiographic osteoarthritis development: Data and biospecimens from the osteoarthritis initiative [0.03%]
外周血DNA甲基化改变可预测放射性骨关节炎发病：来自骨关节炎计划的数据和生物样本
Cindy Miranda Brawner,Gabriella Dyson,Montana Barrett et al.
Cindy Miranda Brawner et al.
Objective: The lack of biomarkers to predict knee osteoarthritis (OA) progression is a key unmet need in the OA field. The objective of this study was to evaluate epigenetic changes in baseline peripheral blood cells of h...
Development and validation of a generalisable survival model to predict osteoarthritis progression [0.03%]
一种可通用的生存模型用于预测骨关节炎发展的开发和验证研究
H H T Li,L C Chan,P K Chan et al.
H H T Li et al.
Objective: To develop and validate a transfer-learning survival model to predict progression end-stage knee osteoarthritis (esKOA) or receive knee replacement (KR). ...
Low-level laser therapy in osteoarthritic pain: A narrative review with an approach to integrated clinical use [0.03%]
低水平激光疗法治疗骨关节炎性疼痛：综合临床应用的叙事综述
S N Hennessy,G D Corcoran
S N Hennessy
Objective: The authors examine how Low-level laser therapy (LLLT) can be used in osteoarthritis (OA) management. LLLT has not, as yet, been widely integrated into OA management, either as a stand-alone modality or in conj...
Cross-sectional associations of radiographic multiple joint osteoarthritis and symptoms, laboratory values and the gut microbiota: A multimodal study in humans and pet dogs [0.03%]
放射性多关节骨关节炎的横断面联合与症状、实验室检查值和肠道微生物：人类和宠物狗的多模式研究
Amanda E Nelson,Liubov Arbeeva,Kelly Johnson et al.
Amanda E Nelson et al.
Objective: To describe the frequency of multiple joint osteoarthritis (MJOA) and symptoms, and associations with fecal microbial diversity and composition, in cohorts of humans and dogs. ...
Artificial intelligence in osteoarthritis research: summary of the 2025 OARSI pre-congress workshop [0.03%]
骨关节炎研究中的人工智能：2025年OARSI大会前工作坊内容总结
Matthew S Harkey,Kerry E Costello,Bella Mehta et al.
Matthew S Harkey et al.
Objective: Artificial intelligence (AI) is transforming musculoskeletal research, offering new approaches to diagnosis, prognosis, and patient management in osteoarthritis (OA). However, implementation and ethical challen...
Organ-on-chip technologies: Novel tools with the potential to revolutionize osteoarthritis research and clinical development [0.03%]
芯片器官技术：有望重塑骨关节炎研究和临床开发的新型工具
Carlo Alberto Paggi
Carlo Alberto Paggi
Objective: To critically evaluate the evolution of in vitro models for osteoarthritis (OA) research, with a specific focus on organ-on-chip (OOC) technologies, and to discuss their potential to overcome the limitations of...
A proteomics investigation of primary human articular chondrocyte isolation [0.03%]
人源性关节软骨细胞分离的蛋白质组学研究
Abby Brumwell,Simran Raheja,William Cawley et al.
Abby Brumwell et al.
Objective: Human primary articular chondrocytes (hPACs) are routinely isolated from articular cartilage for pre-clinical OA research. Collagenase digest of tissue is an essential step, yet the impact of lengthy enzymatic ...