On the waiting list for joint replacement for knee osteoarthritis: Are first-line treatment recommendations implemented? [0.03%]
膝骨关节炎人工关节置换的等待名单:是否实施一线治疗建议?
A Cronström,H Nero,L S Lohmander et al.
A Cronström et al.
Objective: To investigate to what extent individuals participated in guideline-based first-line treatments before being assigned to a wait list for knee replacement for osteoarthritis (OA), and to what extent they were re...
Assessing in vivo articular cartilage mechanosensitivity as outcome of high tibial osteotomy in patients with medial compartment osteoarthritis: Experimental protocol [0.03%]
高位胫骨截骨术后评估体内关节软骨的力学敏感性作为内侧间室骨关节炎的结果:实验方案
Annegret Mündermann,Werner Vach,Geert Pagenster et al.
Annegret Mündermann et al.
Objective: To propose an experimental protocol for using high tibial osteotomy (HTO) as a model for studying in vivo biological effects of large permanent changes in ambulatory load. ...
The synovial fluid from patients with focal cartilage defects contains mesenchymal stem/stromal cells and macrophages with pro- and anti-inflammatory phenotypes [0.03%]
来自局部软骨缺损患者的滑液中含有间充质干细胞/基质细胞和具有促炎和抗炎表型的巨噬细胞
John Garcia,Charlotte Hulme,Claire Mennan et al.
John Garcia et al.
Objective: The synovial fluid (SF) of patients with focal cartilage defects contains a population of poorly characterised cells that could have pathophysiological implications in early osteoarthritis and joint tissue repa...
Repeatability of quantification of extrusion of the medial meniscus in knee osteoarthritis using three-dimensional models [0.03%]
基于三维模型定量评估膝骨关节炎内侧半月板移位的可重复性研究
Goro Watanabe,Kenji Hoshi,Masashi Sadakiyo et al.
Goro Watanabe et al.
Objective: Meniscal damage is one of risk factors for the development of knee osteoarthritis (KOA). Medial meniscal extrusion (MME) is associated with the progression of cartilage loss in the medial compartment. The objec...
The association of plasma IL-1Ra and related cytokines with radiographic severity of early knee osteoarthritis [0.03%]
血浆IL-1Ra及相关细胞因子与膝骨性关节炎影像学分级的关系研究
Cheryl Ann Ma,Sureka Naidu Rajandran,Jin Liu et al.
Cheryl Ann Ma et al.
Objective: We aimed to evaluate the association between inflammatory biomarkers in peripheral blood and severity of knee osteoarthritis (OA). Methods: ...
Jeffrey N Katz,Tuhina Neogi,Leigh F Callahan et al.
Jeffrey N Katz et al.
Objective: To summarize proceedings of a workshop convened to discuss advances in disease modifying osteoarthritis (OA) drugs and regulatory challenges in bringing these drugs to market. ...
Course and predictors of upper leg muscle strength over 48 months in subjects with knee osteoarthritis: Data from the osteoarthritis initiative [0.03%]
膝骨关节炎受试者48个月内股肌力量的变化及预测因素:来自骨关节炎计划的数据
A H de Zwart,M van der Leeden,L D Roorda et al.
A H de Zwart et al.
Objectives: Weakness of upper leg muscles has a negative impact on future disease and functional status in subjects with knee osteoarthritis (OA). The aims of the present study were to (i) describe the course of muscle st...
Evaluation of serum ARGS neoepitope as an osteoarthritis biomarker using a standardized model for exercise-induced cartilage extra cellular matrix turnover [0.03%]
使用基于运动诱导软骨细胞外基质转换的标准模型评估血清ARGS新表位作为骨关节炎生物标志物的效果
Jonathan J Bjerre-Bastos,Henning Bay Nielsen,Jeppe R Andersen et al.
Jonathan J Bjerre-Bastos et al.
Objective: To propose a standardized model for exercise-induced cartilage turnover and investigate residual levels and dynamics of biomarker serum ARGS (sARGS) in primary osteoarthritis (OA) patients and a supportive grou...
Stakeholder views about a novel consumer health resource for knee osteoarthritis [0.03%]
膝骨关节炎新型消费者健康资源的相关方观点
Ben Darlow,Melanie Brown,Rebecca Grainger et al.
Ben Darlow et al.
Objective: This study aimed to explore consumers', clinicians', and arthritis advocates' perceptions of a novel osteoarthritis (OA) information booklet that challenged existing beliefs, integrated a biopsychosocial perspe...
Sick leave before and after arthroscopic partial meniscectomy due to traumatic meniscal tear [0.03%]
创伤性半月板撕裂行关节镜部分半月板切除术前后的病假情况
Dan Bergkvist,Leif E Dahlberg,Jonas Bloch Thorlund et al.
Dan Bergkvist et al.
Objective: There is limited knowledge on sick leave associated with arthroscopic partial meniscectomy (APM) due to traumatic meniscal tear and its potential gender differences. Thus, our aim was to determine gender-specif...