Course and predictors of upper leg muscle strength over 48 months in subjects with knee osteoarthritis: Data from the osteoarthritis initiative [0.03%]
膝骨关节炎受试者48个月内股肌力量的变化及预测因素：来自骨关节炎计划的数据
A H de Zwart,M van der Leeden,L D Roorda et al.
A H de Zwart et al.
Objectives: Weakness of upper leg muscles has a negative impact on future disease and functional status in subjects with knee osteoarthritis (OA). The aims of the present study were to (i) describe the course of muscle st...
Evaluation of serum ARGS neoepitope as an osteoarthritis biomarker using a standardized model for exercise-induced cartilage extra cellular matrix turnover [0.03%]
使用基于运动诱导软骨细胞外基质转换的标准模型评估血清ARGS新表位作为骨关节炎生物标志物的效果
Jonathan J Bjerre-Bastos,Henning Bay Nielsen,Jeppe R Andersen et al.
Jonathan J Bjerre-Bastos et al.
Objective: To propose a standardized model for exercise-induced cartilage turnover and investigate residual levels and dynamics of biomarker serum ARGS (sARGS) in primary osteoarthritis (OA) patients and a supportive grou...
Stakeholder views about a novel consumer health resource for knee osteoarthritis [0.03%]
膝骨关节炎新型消费者健康资源的相关方观点
Ben Darlow,Melanie Brown,Rebecca Grainger et al.
Ben Darlow et al.
Objective: This study aimed to explore consumers', clinicians', and arthritis advocates' perceptions of a novel osteoarthritis (OA) information booklet that challenged existing beliefs, integrated a biopsychosocial perspe...
Sick leave before and after arthroscopic partial meniscectomy due to traumatic meniscal tear [0.03%]
创伤性半月板撕裂行关节镜部分半月板切除术前后的病假情况
Dan Bergkvist,Leif E Dahlberg,Jonas Bloch Thorlund et al.
Dan Bergkvist et al.
Objective: There is limited knowledge on sick leave associated with arthroscopic partial meniscectomy (APM) due to traumatic meniscal tear and its potential gender differences. Thus, our aim was to determine gender-specif...
Antoine Florin,Cécile Lambert,Christelle Sanchez et al.
Antoine Florin et al.
Background: Proteomic studies of the secretome of skeletal muscle cells can help us understand the processes that govern the synthesis, systemic interactions and organization of skeletal muscle and identify proteins that ...
Clinical outcome is significantly better with spheroid-based autologous chondrocyte implantation manufactured with more stringent cell culture criteria [0.03%]
使用更严格的细胞培养标准制造的基于球体的自体软骨细胞植入物临床结果显著更好
C Eschen,C Kaps,W Widuchowski et al.
C Eschen et al.
Objective: Spherox (CO.DON AG) is an autologous chondrocyte implantation (ACI) product, consisting of spheroids of human autologous matrix-associated chondrocytes. The tendency of primary chondrocytes to dedifferentiate d...
Bridging Disciplines as a pathway to Finding New Solutions for Osteoarthritis a collaborative program presented at the 2019 Orthopaedic Research Society and the Osteoarthritis Research Society International [0.03%]
跨越学科是寻找骨关节炎新解决方案的途径 在2019年骨科研究学会和骨关节炎研究学会国际会议上介绍的一项合作计划
Thomas P Andriacchi,Timothy M Griffin,Richard F Loeser Jr et al.
Thomas P Andriacchi et al.
Objective: To stimulate future research directions that seek solutions for osteoarthritis (OA) at the interface between diverse disciplines and address osteoarthritis (OA) as a serious disease with a complexity that has p...
Psychometric properties of the Neuropathic Pain Scale (NPS) in a knee osteoarthritis population [0.03%]
神经病变疼痛量表(NPS)在膝骨关节炎人群中应用的计量特征分析
Emma C Lape,Faith Selzer,Aileen M Davis et al.
Emma C Lape et al.
Objective: Symptoms resembling neuropathic pain (neuropathic-like symptoms) are prevalent in osteoarthritis (OA) populations. Scales that measure neuropathic-like symptoms frequently were established in groups with true n...
Liver X Receptor activation regulates genes involved in lipid homeostasis in developing chondrocytes [0.03%]
肝X受体激活调节发育中的软骨细胞中涉及脂质稳态的基因
Margaret Man-Ger Sun,Frank Beier
Margaret Man-Ger Sun
Objective: Osteoarthritis (OA) is the most common type of arthritis and causes debilitating symptoms and decreased quality of life. A better understanding of the molecular mechanisms maintaining cartilage health is needed...