Association between changes in muscle strength and pain in persons with meniscal tear and osteoarthritis [0.03%]
半月板撕裂和骨关节炎的人肌肉力量的变化与疼痛之间的联系
James K Sullivan,Swastina Shrestha,Jamie E Collins et al.
James K Sullivan et al.
Objective: Strengthening-based physical therapy (PT) is frequently recommended for persons with knee osteoarthritis (OA) and meniscal tear. On average, knee OA patients experience pain improvement while undergoing PT, but...
Does free-living physical activity improve one-year following total knee arthroplasty in patients with osteoarthritis: A prospective study [0.03%]
骨性关节炎患者在膝关节置换术后一年的日常生活活动能力是否有所提高：一项前瞻研究
Bodor Bin Sheeha,Malcolm Granat,Anita Williams et al.
Bodor Bin Sheeha et al.
Objective: Total knee arthroplasty (TKA) is the gold-standard treatment for end-stage knee osteoarthritis, and the primary expectations are reduced pain and improved function. However, there is conflicting evidence regard...
Change in pain and its relation to change in activity in osteoarthritis [0.03%]
骨关节炎疼痛的改变及其与活动量变化的关系
Matthew J Parkes,Richard K Jones,Suzanne C Carter et al.
Matthew J Parkes et al.
Objective: Trials testing promising interventions in knee osteoarthritis (OA) often fail to show pain reductions. This may be due to change in activity whereby a person's pain decreases, leading them to increase their act...
Mesenchymal stem cells and their application to rotator cuff pathology: A meta-analysis of pre-clinical studies [0.03%]
间充质干细胞及其在肩袖病变中的应用：前临床研究的荟萃分析
Nicolas Morton-Gonzaba,Daniel Carlisle,Chimobi Emukah et al.
Nicolas Morton-Gonzaba et al.
Background: Rotator cuff injury (RCI) is a leading cause of morbidity in orthopaedics. Advances in regenerative medicine have led to the novel pleiotropic effects of mesenchymal stromal cells (MSCs) as therapeutic agents ...
On the waiting list for joint replacement for knee osteoarthritis: Are first-line treatment recommendations implemented? [0.03%]
膝骨关节炎人工关节置换的等待名单：是否实施一线治疗建议？
A Cronström,H Nero,L S Lohmander et al.
A Cronström et al.
Objective: To investigate to what extent individuals participated in guideline-based first-line treatments before being assigned to a wait list for knee replacement for osteoarthritis (OA), and to what extent they were re...
Assessing in vivo articular cartilage mechanosensitivity as outcome of high tibial osteotomy in patients with medial compartment osteoarthritis: Experimental protocol [0.03%]
高位胫骨截骨术后评估体内关节软骨的力学敏感性作为内侧间室骨关节炎的结果：实验方案
Annegret Mündermann,Werner Vach,Geert Pagenster et al.
Annegret Mündermann et al.
Objective: To propose an experimental protocol for using high tibial osteotomy (HTO) as a model for studying in vivo biological effects of large permanent changes in ambulatory load. ...
The synovial fluid from patients with focal cartilage defects contains mesenchymal stem/stromal cells and macrophages with pro- and anti-inflammatory phenotypes [0.03%]
来自局部软骨缺损患者的滑液中含有间充质干细胞/基质细胞和具有促炎和抗炎表型的巨噬细胞
John Garcia,Charlotte Hulme,Claire Mennan et al.
John Garcia et al.
Objective: The synovial fluid (SF) of patients with focal cartilage defects contains a population of poorly characterised cells that could have pathophysiological implications in early osteoarthritis and joint tissue repa...
Repeatability of quantification of extrusion of the medial meniscus in knee osteoarthritis using three-dimensional models [0.03%]
基于三维模型定量评估膝骨关节炎内侧半月板移位的可重复性研究
Goro Watanabe,Kenji Hoshi,Masashi Sadakiyo et al.
Goro Watanabe et al.
Objective: Meniscal damage is one of risk factors for the development of knee osteoarthritis (KOA). Medial meniscal extrusion (MME) is associated with the progression of cartilage loss in the medial compartment. The objec...
The association of plasma IL-1Ra and related cytokines with radiographic severity of early knee osteoarthritis [0.03%]
血浆IL-1Ra及相关细胞因子与膝骨性关节炎影像学分级的关系研究
Cheryl Ann Ma,Sureka Naidu Rajandran,Jin Liu et al.
Cheryl Ann Ma et al.
Objective: We aimed to evaluate the association between inflammatory biomarkers in peripheral blood and severity of knee osteoarthritis (OA). Methods: ...
Jeffrey N Katz,Tuhina Neogi,Leigh F Callahan et al.
Jeffrey N Katz et al.
Objective: To summarize proceedings of a workshop convened to discuss advances in disease modifying osteoarthritis (OA) drugs and regulatory challenges in bringing these drugs to market. ...