Infrared spectroscopy of serum fails to identify early biomarker changes in an equine model of traumatic osteoarthritis [0.03%]
红外光谱在创伤性骨关节炎马模型中不能识别血清的早期生物标志物变化
L Panizzi,M Vignes,K E Dittmer et al.
L Panizzi et al.
Objective: to determine the accuracy of infrared (IR)-based serum biomarker profiling to differentiate horses with early inflammatory changes associated with a traumatically induced model of equine carpal osteoarthritis (...
The role of Platelet-Rich Plasma (PRP) intraarticular injections in restoring articular cartilage of osteoarthritic knees. A systematic review and meta-analysis [0.03%]
血小板-rich血浆（PRP）关节内注射在恢复骨关节炎膝关节软骨中的作用。系统评价和荟萃分析
Apostolos D Prodromidis,Charalambos P Charalambous,Emma Moran et al.
Apostolos D Prodromidis et al.
Objective: To assess the effect of PRP on knee articular cartilage content (thickness/volume) and examine the correlation between cartilage changes and clinical outcomes in patients with knee OA. ...
Association of plasma microbial composition with a leaky gut in obesity-related osteoarthritis: An exploratory study [0.03%]
肥胖相关性骨关节炎中肠道渗漏与血浆微生物组成的关系：一项探索性研究
Liubov Arbeeva,M Andrea Azcarate-Peril,Yang Cui et al.
Liubov Arbeeva et al.
Objective: To examine the plasma microbiome for differences between obese individuals with and without osteoarthritis (OA) and its association with serum lipopolysaccharide (LPS). ...
Barriers and enablers to health care providers assessment and treatment of knee osteoarthritis in persons with type 2 diabetes mellitus: A qualitative study using the Theoretical Domains Framework [0.03%]
2型糖尿病患者膝骨关节炎评估和治疗的障碍与促进因素：采用理论领域框架的质性研究
Lauren K King,Owen Krystia,Esther J Waugh et al.
Lauren K King et al.
Objectives: Symptomatic knee osteoarthritis (OA) commonly co-exists in persons with Type 2 diabetes (T2DM) and may impede diabetes self-management. Yet, OA is often underdiagnosed and undertreated due to competing health ...
Effects of psychological distress on the general health to self-reported pain and function outcome relationship in knee arthroplasty: A causal mediation study [0.03%]
心理痛苦对膝关节置换术中自报的疼痛和功能结局与一般健康状况关系的影响：一项因果中介研究
Daniel L Riddle,S Reza Jafarzadeh
Daniel L Riddle
Objectives: We examined two potential causal pathways that could be intervention targets to enhance knee arthroplasty outcomes. Data from a no-effect trial of persons with moderate to high pain catastrophizing were used t...
A two-stage digestion of whole murine knee joints for single-cell RNA sequencing [0.03%]
用于单细胞RNA测序的小鼠膝关节两步消化法
Dustin M Leale,Linan Li,Matthew L Settles et al.
Dustin M Leale et al.
Objective: Single-cell RNA sequencing (scRNA-seq) is a powerful technology that can be applied to the cells populating the whole knee in the study of joint pathology. The knee contains cells embedded in hard structural ti...
Wait time management strategies at centralized intake system for hip and knee replacement surgery: A need for a blended evidence-based and patient-centered approach [0.03%]
集中式入院系统中髋膝关节置换手术的等待时间管理策略：需要采取基于证据和以患者为中心相结合的方法
Deborah A Marshall,Diane P Bischak,Farzad Zaerpour et al.
Deborah A Marshall et al.
Objectives: Delays in access to specialty care and elective hip and knee total joint replacement (TJR) surgery remain a major concern among patients with osteoarthritis (OA) in Canada. Centralized intake systems as a wait...
Objective performance tests assess aspects of function not captured by self-report in knee osteoarthritis [0.03%]
客观性能测试评估膝骨关节炎中自我报告未涵盖的功能方面
Faith Selzer,Michael B Zarra,Lindsey A MacFarlane et al.
Faith Selzer et al.
Objective: Knee osteoarthritis (OA) can substantially limit function, which can be assessed both objectively and subjectively. We examined whether objective performance tests are associated with self-reported function. ...
Experimental models to study osteoarthritis pain and develop therapeutics [0.03%]
研究骨关节炎疼痛和开发治疗药物的实验模型
Kanyakorn Riewruja,Meagan Makarczyk,Peter G Alexander et al.
Kanyakorn Riewruja et al.
Pain is the predominant symptom of osteoarthritis (OA) that drives patients to seek medical care. Currently, there are no pharmacological treatments that can reverse or halt the progression of OA. Safe and efficacious medications for long-t...
Dynamic compression inhibits cytokine-mediated type II collagen degradation [0.03%]
动态压缩抑制细胞因子介导的II型胶原降解
Amalie Engstrøm,Frederik S Gillesberg,Anne-Christine Bay Jensen et al.
Amalie Engstrøm et al.
Objective: To examine the effect of dynamic compressive loading applied intermittently on bovine cartilage explants stimulated with proinflammatory cytokines over 21 days. ...