Safety and efficacy of newer biologics DMARDs in the management of rheumatoid arthritis: A systematic review [0.03%]
更新的生物制剂DMARDs在类风湿关节炎管理中的安全性和疗效:系统性回顾
Basiru Ahmad Zago,A Priyadharshini,T M Vijayakumar
Basiru Ahmad Zago
Objective: To analyze the safety and efficacy of certain biologics DMARDs (Adalimumab, Baricitinib, Pefacitinib and Sirukumab) either used alone or as a combination with MTX for management of rheumatoid arthritis. ...
Proportion of patients with hip osteoarthritis in primary care identified by differing clinical criteria: a cross-sectional study of 4699 patients [0.03%]
不同临床标准在初级保健中识别的髋骨关节炎患者比例:一项包含4699名患者的横断面研究
James J Young,Søren T Skou,Bart W Koes et al.
James J Young et al.
Objective: Differing clinical criteria for hip osteoarthritis (OA) are applied in primary care, but little is known regarding the utility of these criteria. The aim of this study was to evaluate and compare the proportion...
Recombinant human gelsolin promotes the migration of human articular cartilage chondrocytes by regulating gene expression in vitro [0.03%]
重组人凝溶蛋白通过调节基因表达促进人体关节软骨软骨细胞迁移的研究
Jessica Feldt,Jessica Welss,Verena Schropp et al.
Jessica Feldt et al.
Objective: It is known that recombinant human gelsolin (rhuGSN) supports wound closure and migration processes in avascular tissue. Since articular cartilage degradation plays an important role in osteoarthritis (OA), we ...
Correlation of damage score in PTOA with changes in stress on cartilage in an ovine model [0.03%]
损伤评分与软骨应力改变的相关性研究(Ovine模型PTOA)
Paris Vakiel,Mehdi Shekarforoush,Christopher R Dennison et al.
Paris Vakiel et al.
Objective: There is a high risk of developing osteoarthritis (OA) following traumatic injury to the knee. Severe ligament injuries can disrupt the integrity of the multicomponent knee at both biological and biomechanical ...
Framework for modulating ambulatory load in the context of in vivo mechanosensitivity of articular cartilage [0.03%]
活体关节软骨机敏性背景下调节行走负载的框架结构
Simon Herger,Corina Nüesch,Anna-Maria Liphardt et al.
Simon Herger et al.
Objective: Different stress modalities have been used to provoke a load induced mechanoresponse in blood markers of articular cartilages. The challenge in in vivo experiments is to alter specific loading characteristics. ...
Symptomatic knee osteoarthritis is associated with worse but stable quality of life and physical function regardless of the compartmental involvement: Data from the OAI [0.03%]
有症状的膝骨关节炎与无论受累部位的质量生活和身体功能较差但稳定有关:来自OAI的数据
Jesse M Charlton,Jean-Francois Esculier,Dylan Kobsar et al.
Jesse M Charlton et al.
Objective: To test whether combined patellofemoral and tibiofemoral osteoarthritis (OA), in addition to symptoms, is associated with greater changes in quality of life and objective physical function measures when compare...
Colony housing promotes structural and functional changes during surgically induced osteoarthritis in rats [0.03%]
聚居饲养促进大鼠手术性骨关节炎期间的组织结构与功能变化
C Brenneis,S Menges,A Westhof et al.
C Brenneis et al.
Objective: The aim of the study was to investigate how social housing with high locomotion activity affects experimental osteoarthritis (OA) in rats. Desi...
Cost-effectiveness of dental antibiotic prophylaxis in total knee arthroplasty recipients with type II diabetes mellitus [0.03%]
牙科抗生素预防在II型糖尿病全膝关节置换术受者中的成本效果分析
Elizabeth E Stanley,Taylor P Trentadue,Karen C Smith et al.
Elizabeth E Stanley et al.
Objective: Type II diabetes mellitus (T2DM) is prevalent in knee osteoarthritis (OA) patients undergoing total knee arthroplasty (TKA) and increases risk for prosthetic joint infection (PJI). We examined the cost-effectiv...
The cost-effectiveness of recommended adjunctive interventions for knee osteoarthritis: Results from a computer simulation model [0.03%]
膝骨关节炎所推荐的联合干预措施的成本效果分析:来自计算机模拟模型的结果
Ross Wilson,Jason Chua,Andrew M Briggs et al.
Ross Wilson et al.
Objective: To estimate the potential lifetime health gains, healthcare costs, and cost-effectiveness of recommended adjunctive treatments for knee osteoarthritis delivered in addition to established core treatments, relat...
Reliability and concurrent validity of three-dimensional ultrasound for quantifying knee cartilage volume [0.03%]
三维超声评定膝关节软骨体积的可靠性和同伦效度研究
S Papernick,R Dima,D J Gillies et al.
S Papernick et al.
Objective: The goal of this study was to test the reliability and validity of a handheld mechanical three-dimensional (3D) ultrasound (US) device for quantifying femoral articular cartilage (FAC) against the current clini...