An online individualised patient decision aid improves the quality of decisions in patients considering total knee arthroplasty in routine care: A randomized controlled trial [0.03%]
在线个性化病人决策辅助工具可以提高常规护理中考虑全膝关节成形术的病人的决策质量：随机对照试验
Nick Bansback,Logan Trenaman,Karen V MacDonald et al.
Nick Bansback et al.
Objective: The objective of this study was to evaluate the effectiveness of an online patient decision aid with individualised potential outcomes of surgery, on the quality of decisions for knee replacement surgery in rou...
Technical performance of a proximity extension assay inflammation biomarker panel with synovial fluid [0.03%]
滑膜液中邻近延伸测定炎症生物标志物面板的技术性能
André Struglics,Staffan Larsson,L Stefan Lohmander et al.
André Struglics et al.
Reflections from the 2021 OARSI clinical trial symposium: Considerations for understanding biomarker assessments in osteoarthritis drug development - Should future studies focus on disease activity, rather than status? [0.03%]
2021年OARSI临床试验研讨会反思：了解骨关节炎药物开发中生物标志物评估的注意事项 - 未来的研究是否应该关注疾病活动性而不是状态？
M A Karsdal,J Tambiah,M C Hochberg et al.
M A Karsdal et al.
Objective: Osteoarthritis (OA) is heterogeneous disease, for which drug development has proven to be challenging, both facilitated and hampered by changing guidelines. This is evident by the current lack of approved treat...
Patterns of progression differ between Kellgren-Lawrence 2 and 3 knees fulfilling different definitions of a cartilage-meniscus phenotype in the Foundation for National Institutes of Health Osteoarthritis Biomarkers study (FNIH) [0.03%]
在满足cartilage-meniscus表型不同定义的Kellgren-Lawrence 2和3膝中，其进展模式存在差异——来自国家卫生研究院骨关节炎生物标志物研究基金会(FNIH)的研究
Frank W Roemer,Jamie E Collins,David J Hunter et al.
Frank W Roemer et al.
Objective: Aim was to describe three definitions for an MRI-defined cartilage-meniscus phenotype and to report phenotypic progression in Kellgren-Lawrence (KL) 2 and 3 knees over 48 months. ...
Comparative transcriptional profiling of regenerating damaged knee joints in two animal models of the newt Notophthalmus viridescens strengthens the role of candidate genes involved in osteoarthritis [0.03%]
两种火蜥Notophthalmus viridescens模型再生受损膝关节的比较转录谱强化了参与骨关节炎候选项基因的作用
Matthias Geyer,Christiane Schönfeld,Carina Schreiyäck et al.
Matthias Geyer et al.
Objectives: To compare joint regeneration in adult newts (N. viridescens) upon both newly established surgical removal and previously reported enzymatic destruction of articular cartilage to identify molecular factors and...
Trends in prevalence of hip osteoarthritis over a 10-year period in Japan: The ROAD study 2005-2015 [0.03%]
日本10年期间髋骨关节炎患病率的变化趋势：2005-2015年的ROAD研究
Toshiko Iidaka,Chiaki Horii,Shigeyuki Muraki et al.
Toshiko Iidaka et al.
Objective: The trends in prevalence of hip osteoarthritis (OA) over a 10-year period among Japanese men and women were investigated using the data from the Research on Osteoarthritis/osteoporosis Against Disability study....
Synovial tissue metabolomic profiling reveal biomarkers of synovial inflammation in patients with osteoarthritis [0.03%]
滑膜组织代谢组学分析揭示了骨关节炎患者滑膜炎症的生物标志物
Jessica D Murillo-Saich,Roxana Coras,Robert Meyer et al.
Jessica D Murillo-Saich et al.
Objective: Inflammatory responses are associated with changes in tissue metabolism. Prior studies find altered metabolomic profiles in both the synovial fluid (SF) and serum of osteoarthritis subjects. Our study determine...
The effect of intra-articular extended-release triamcinolone acetonide on OARSI-recommended physical performance measures in adults with bilateral symptomatic knee osteoarthritis [0.03%]
膝关节腔长效倍他米松对双侧有症状的膝骨关节炎成人OARSI推荐的身体机能测量指标的影响
N A Segal,J C Alm
N A Segal
Objective: While the effect of triamcinolone acetonide extended-release (TA-ER) on reducing knee osteoarthritis (OA) pain has been reported, the effects on physical performance are incompletely understood. This open label...
Validation of canadian health administrative data algorithms for estimating trends in the incidence and prevalence of osteoarthritis [0.03%]
加拿大卫生管理数据算法在估计骨关节炎的发病率和患病率趋势中的验证问题研究
Jessica Widdifield,R Liisa Jaakkimainen,Jodi M Gatley et al.
Jessica Widdifield et al.
Objective: To estimate the 1) accuracy of algorithms for identifying osteoarthritis (OA) using health administrative data; and 2) population-level OA prevalence and incidence over time in Ontario, Canada. ...
Evaluation of spin in the abstracts of systematic reviews and meta-analyses covering surgical management, or quality of life after surgical management, of osteoarthritis of the knee [0.03%]
膝关节骨性关节炎外科治疗或外科治疗后生活质量系统评价及meta分析摘要中倾向性的评估
Parker Siex,William Nowlin,Ryan Ottwell et al.
Parker Siex et al.
Objective: Our primary objective was to identify the prevalence of spin - misleading reporting practices that overemphasize benefit or underemphasize harm - within the abstracts of systematic reviews and meta-analyses foc...