Time to first and sustained improvement in WOMAC domains among patients with osteoarthritis receiving tanezumab [0.03%]
使用坦泽单抗治疗的骨关节炎患者WOMAC量表各领域首次和持续改善的时间分析
D J Hunter,T J Schnitzer,J Hall et al.
D J Hunter et al.
Objective: To assess onset of effect in three placebo- or nonsteroidal anti-inflammatory drug (NSAID)-controlled trials of tanezumab in patients with moderate-to-severe osteoarthritis. ...
Identifying small molecules for protecting chondrocyte function and matrix integrity after controlled compressive injury [0.03%]
在受控压缩损伤后识别保护软骨细胞功能和基质完整性的小型分子
Saleh Al Jundi,Jerahme R Martinez,Jake Cresta et al.
Saleh Al Jundi et al.
Objective: Articular cartilage injury is central for the development of post-traumatic osteoarthritis (PTOA). With few disease-modifying therapies successful at offsetting progressive osteoarthritis (OA), our goal is to u...
An open-label, single-arm trial of cryoneurolysis for improvements in pain, activities of daily living and quality of life in patients with symptomatic ankle osteoarthritis [0.03%]
用于治疗有症状的踝关节骨关节炎患者疼痛，日常生活活动和生活质量的冷冻神经溶解的开放标签，单臂试验研究
Thomas A Perry,Neil A Segal
Thomas A Perry
Objective: Cryoneurolysis, cold-induced reversible conduction block of peripheral nerves, is an effective treatment for reducing knee osteoarthritis (OA) symptoms and opioid use following knee arthroplasty. There are howe...
"Much better than I thought it was going to be": Telehealth delivered group-based education and exercise was perceived as acceptable among people with knee osteoarthritis [0.03%]
“比我想的要好得多”：远程健康提供的团体教育和运动对于膝骨关节炎患者来说是可被接受的
A M Ezzat,E Bell,J L Kemp et al.
A M Ezzat et al.
Objective: To understand patient perceived acceptability of participating in a telehealth delivered group-based education and exercise-therapy program for knee osteoarthritis. ...
Developing and internally validating a prediction model for total knee replacement surgery in patients with osteoarthritis [0.03%]
骨关节炎患者全膝置换手术的预测模型的建立及内部验证
Sharmala Thuraisingam,Patty Chondros,Jo-Anne Manski-Nankervis et al.
Sharmala Thuraisingam et al.
Objective: The objective of this study was to develop and internally validate a clinical algorithm for use in general practice that predicts the probability of total knee replacement (TKR) surgery within the next five yea...
Automatic femoral articular cartilage segmentation using deep learning in three-dimensional ultrasound images of the knee [0.03%]
利用深度学习对膝关节三维超声图像中的股骨关节软骨进行自动分割
Carla du Toit,Nathan Orlando,Sam Papernick et al.
Carla du Toit et al.
Objective: This study aimed to develop a deep learning-based approach to automatically segment the femoral articular cartilage (FAC) in 3D ultrasound (US) images of the knee to increase time efficiency and decrease rater ...
Effectiveness of remote exercise programs in reducing pain for patients with knee osteoarthritis: A systematic review of randomized trials [0.03%]
远程运动项目对膝骨关节炎患者减痛的有效性：随机试验的系统评价
C G McHugh,A M Kostic,J N Katz et al.
C G McHugh et al.
Objective: Remote knee osteoarthritis (OA) management programs are becoming more popular. This systematic review examined the efficacy of remote exercise programs for relieving pain in persons with knee OA. ...
CD90-positive stromal cells associate with inflammatory and fibrotic changes in modic changes [0.03%]
CD90阳性间质细胞与Modic改变中的炎症和纤维变性有关
Stefan Dudli,Agnieszka Karol,Luca Giudici et al.
Stefan Dudli et al.
Objective: Modic changes (MC) are vertebral bone marrow lesions seen on magnetic resonance images, that associate with disc degeneration and low back pain (LBP). Few studies described MC histopathology qualitatively based...
The association between statistical shape modeling-defined hip morphology and features of early hip osteoarthritis in young adult football players: Data from the femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study [0.03%]
统计形状建模定义的青年轻型足球运动员髋部形态与早期髋骨关节炎特征之间的关联：来自股骨头 acetabular 狭窄和髋骨关节炎队列（FORCe）研究的数据
M M A van Buuren,J J Heerey,A Smith et al.
M M A van Buuren et al.
Objective: To explore the relationship between radiographic hip shape and features of early hip osteoarthritis (OA) on magnetic resonance imaging (MRI) in young male and female football players without radiographic hip OA...
Association of presurgical circulating MicroRNAs with 1-year postsurgical pain reduction in spine facet osteoarthritis patients with lumbar spinal stenosis [0.03%]
术前循环MicroRNAs与腰椎间盘突出合并脊椎小关节骨性关节炎患者术后一年疼痛减轻的关联性研究
Starlee Lively,Marie Milliot,Pratibha Potla et al.
Starlee Lively et al.
Purpose: Up to 30% of spine facet osteoarthritis patients with lumbar spinal stenosis (SF-OA + LSS) have little to no improvement in their pain after surgery. Lack of meaningful improvement in pain following surgery p...