Development of a highly sensitive chemiluminescence immunoassay for quantification of aggrecanase-generated ARGS aggrecan fragments in serum [0.03%]
用于量化血清中aggrecanase产生的ARGS软骨素片段的高灵敏度化学发光免疫测定法的开发
Yi He,Kamilla E Jensen,Anne Sofie Siebuhr et al.
Yi He et al.
Objective: Cartilage degradation is a hallmark of osteoarthritis (OA). Aggrecan, a major proteoglycan of articular cartilage extracellular matrix (ECM), is degraded by ADAMTS-5 resulting in the release of ARGS-G2 fragment...
Avoiding unconscious injection of vial-derived rubber particles during intra-articular drug administration [0.03%]
在关节内药物注射过程中避免无意中注入安瓿衍生的橡胶颗粒
Andreas Hecker,Agostino Di Maro,Emanuel F Liechti et al.
Andreas Hecker et al.
Objective: Vial coring describes the occurrence of small rubber particles, which are formed by needles when perforating vial stoppers. These particles may be aspirated along with the drug. Unconscious injection of rubber ...
Telemedical versus onsite treatment at an orthopaedic university clinic: Study of 280 consecutive patients [0.03%]
远程医疗与大学骨科诊所的现场治疗：对280例连续入组患者的分析
Pabinger Christof,Lothaller Harald,Leys Nicolas et al.
Pabinger Christof et al.
Objective: Compare a telemedical treatment (distant working) with an onsite treatment. Telemedical services have been used frequently in non-surgical disciplines. It remains unclear if orthopaedic outpatients can be treat...
Measuring adherence to unsupervised, conservative treatment for knee osteoarthritis: A systematic review [0.03%]
膝骨关节炎无监督保守治疗的依从性测量：系统评价
Vicky Duong,Matthew S Daniel,Manuela L Ferreira et al.
Vicky Duong et al.
Objective: To describe the measurement of adherence to unsupervised, conservative treatments for knee osteoarthritis (OA), including the methods of adherence measurement, parameters for assessing adherence and any values ...
Osteoarthritis Research Society International (OARSI): Past, present and future [0.03%]
骨关节炎研究学会国际组(OARSI)：过去、现在和未来
Ali Mobasheri,Gun-Il Im,Jeffrey N Katz et al.
Ali Mobasheri et al.
We provide a detailed account of the origin and establishment of the Osteoarthritis Research Society International (OARSI) and celebrate its history from inception to the current day. We discuss the mission, vision and strategic objectives ...
Calcified cartilage revealed in whole joint by X-ray phase contrast imaging [0.03%]
X射线相位对比成像技术在全关节中揭示的钙化软骨
Ludovic Broche,Bertrand Favier,Hélène Rougé-Labriet et al.
Ludovic Broche et al.
Objective: X-ray Phase Contrast Imaging (PCI) is an emerging modality that will be in the next few years available in a wider range of preclinical set-ups. In this study, we compare this imaging technique with conventiona...
The histopathology of the humeral head in glenohumeral osteoarthritis [0.03%]
肩肱关节骨性关节炎的肱骨头的组织病理变化研究
A P Matson,Z Kunkel,V A Bernal-Crespo et al.
A P Matson et al.
Objective: The histopathologic wear patterns in glenohumeral osteoarthritis (GOA) have not been described. The aims of the study were to a) describe the histopathology of humeral head wear patterns in patients with end-st...
Iron triggers the early stages of cartilage degeneration in vitro: The role of articular chondrocytes [0.03%]
铁离子引发体外软骨退变的早期阶段：关节软骨细胞的作用
A V Ferreira,T L Duarte,S Marques et al.
A V Ferreira et al.
Objective: Arthropathy is a major clinical problem in patients with hemochromatosis, the most common genetic disorder of iron overload. The pathological features of hemochromatosis arthropathy (HA) are heterogeneous and i...
Predictors of Co-occurring Cardiovascular and Gastrointestinal Disorders among Elderly with Osteoarthritis [0.03%]
预测患有骨关节炎的老年人同时发生心血管和胃肠疾病的预测因素
Jayeshkumar Patel,Amit Ladani,Nethra Sambamoorthi et al.
Jayeshkumar Patel et al.
Objective: To identify the leading predictors of co-occurring cardiovascular or gastrointestinal disorders (CV-GID) in a real-world cohort of elderly with osteoarthritis (OA). ...
Identification of a differential metabolite-based signature in patients with late-stage knee osteoarthritis [0.03%]
晚期膝骨关节炎患者差异代谢物特征的识别
Jason S Rockel,Mehdi Layeghifard,Y Raja Rampersaud et al.
Jason S Rockel et al.
Objective: Multiple disease phenotypes have been identified in knee osteoarthritis (OA) patients based on anthropometric, sociodemographic and clinical factors; however, differential systemic metabolite-based signatures i...