Frequency of multisite non-hand joint involvement in patients with thumb-base osteoarthritis, and associations with functional and patient-reported outcomes [0.03%]
拇指基底部骨关节炎患者多关节受累的患病率及其与功能和患者报告结果之间的关系
Anthony V Perruccio,Elizabeth M Badley,Daniel Antflek et al.
Anthony V Perruccio et al.
Purpose: In OA studies, the focus often is on an index-joint; other affected joint sites are often overlooked. In this thumb-base OA study, we documented the frequency of symptomatic non-hand joint sites and investigated ...
Interleukin-6 receptor blockade improves bone healing following ischemic osteonecrosis in adolescent mice [0.03%]
针对青少年小鼠缺血性骨坏死的白细胞介素-6受体阻断可促进骨折愈合
Gen Kuroyanagi,Nobuhiro Kamiya,Ryosuke Yamaguchi et al.
Gen Kuroyanagi et al.
Objective: Juvenile ischemic osteonecrosis (JIO) of the femoral head is one of the most serious hip disorders causing a permanent deformity of the femoral head in childhood. We recently reported that interleukin 6 (IL-6) ...
An invigorating journey towards better function and well-being: A qualitative study of knee osteoarthritis patients' experiences with an online exercise and education intervention [0.03%]
一项令人振奋的改善功能和生活质量之旅：膝关节炎患者在线锻炼和教育干预措施体验的质性研究
Charlotte Simonÿ,Brian Clausen,Malene Beck et al.
Charlotte Simonÿ et al.
Objective: To explore what it means for patients with knee osteoarthritis (OA) to engage in online delivered exercise and education. Method: ...
Development of a novel animal model of rotator cuff tear arthropathy replicating clinical features of progressive osteoarthritis with subchondral bone collapse [0.03%]
一种新的肩袖撕裂性关节病动物模型的发展，该模型复制进行性骨关节炎伴软骨下骨塌陷的临床特征
T Ijuin,T Iuchi,H Tawaratsumida et al.
T Ijuin et al.
Objective: To establish an animal model of modified cuff tear arthropathy (mCTA) in order to better replicate the pathophysiology associated with rotator cuff tear-induced humeral head collapse. ...
A systematic review demonstrating correlation of MRI compositional parameters with clinical outcomes following articular cartilage repair interventions in the knee [0.03%]
一项系统回顾：膝关节软骨修复术后磁共振组成参数与临床结局的相关性分析
Beth Lineham,Harin Wijayathunga,Emma Moran et al.
Beth Lineham et al.
Objective: Compositional-MRI parameters enable the assessment of cartilage ultrastructure. Correlation of these parameters with clinical outcomes is unclear. This systematic review investigated the correlation of various ...
Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review [0.03%]
膝MRI生物标志物与至少一年前遭受前交叉韧带损伤相关的结构、功能和症状变化——系统性综述
Oliver O&#x;Sullivan,Peter Ladlow,Kat Steiner et al.
Oliver O&#x;Sullivan et al.
Introduction: Osteoarthritis (OA) results from various aetiologies, including joint morphology, biomechanics, inflammation, and injury. The latter is implicated in post-traumatic OA, which offers a paradigm to identify po...
Anabolic phenotype in cartilage-specific mitogen-inducible gene-6 knockout mice is independent of transforming growth factor-α [0.03%]
软骨特异性诱导型基因-6敲除小鼠的同化表型独立于转化生长因子-α作用
Ermina Hadzic,Bethia To,Michael A Pest et al.
Ermina Hadzic et al.
Background/objective: Osteoarthritis (OA) is a whole joint disorder with no disease modifying treatment currently available. The Epidermal Growth Factor Receptor (EGFR) signaling pathway plays an important role in cartila...
Is radiographic osteoarthritis associated with pain and disability of the ankle? [0.03%]
放射性骨关节炎与踝部疼痛和残疾有关吗？
S E Kloprogge,N Katier,A K E Mailuhu et al.
S E Kloprogge et al.
Objective: Ankle osteoarthritis (OA) is relatively understudied. It often affects younger people compared to OA in other joints. Evidence on the association between radiographic OA and ankle symptoms remains contradicting...
Effect of 6-week treatment with topical betamethasone dipropionate in patients with symptomatic hand osteoarthritis: A randomized double-blind, placebo-controlled trial [0.03%]
6周外用倍他米松治疗手部骨关节炎症状的效果：随机双盲安慰剂对照试验
Yuanyuan Wang,Mahnuma Mahfuz Estee,Desmond Gan et al.
Yuanyuan Wang et al.
Objective: To examine the efficacy and safety of topical corticosteroid over 6 weeks in patients with symptomatic hand osteoarthritis. Design: ...
Quantification of chondroitin sulfate, hyaluronic acid and N-glycans in synovial fluid - A technical performance study [0.03%]
透明质酸和N-聚糖的定量分析——一项关于滑膜液中硫酸软骨素的技术性能研究
Elin Andersson,Emil Tykesson,L Stefan Lohmander et al.
Elin Andersson et al.
Objective: To validate a quantitative high performance liquid chromatography (HPLC) assay for chondroitin sulfate (CS) and hyaluronic acid (HA) in synovial fluid, and to analyze glycan-patterns in patient samples. ...