Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study [0.03%]
遗传学随机化研究揭示骨关节炎亚型与常见合并症之间的因果关系
Will Thompson,Subhashisa Swain,Sizheng Steven Zhao et al.
Will Thompson et al.
Objective: To investigate the causal association between Osteoarthritis (OA) and five comorbidities: depression, tiredness, multisite chronic pain, irritable bowel syndrome (IBS) and gout. ...
Mask R-CNN provides efficient and accurate measurement of chondrocyte viability in the label-free assessment of articular cartilage [0.03%]
无标记评估关节软骨的Mask R-CNN可有效且准确地测量软骨细胞活力
Hongming Fan,Pei Xu,Xun Chen et al.
Hongming Fan et al.
Objective: Chondrocyte viability (CV) can be measured with the label-free method using second harmonic generation (SHG) and two-photon excitation autofluorescence (TPAF) imaging. To automate the image processing for the l...
Patterns and natural history of hand pain in individuals with symptomatic hand osteoarthritis in a prospective cohort study: A post-hoc analysis of a randomised controlled trial [0.03%]
一项随机对照试验的事后分析：前瞻性队列研究中手骨关节炎症状期个体的手痛模式及自然病史
Mahnuma Mahfuz Estee,Yuanyuan Wang,Yuan Z Lim et al.
Mahnuma Mahfuz Estee et al.
Objective: To investigate the variation in the distribution and the natural history of hand pain over 6 weeks in individuals with symptomatic hand osteoarthritis. ...
Joint biomarker response to mechanical stimuli in osteoarthritis - A scoping review [0.03%]
骨关节炎的机械刺激联合生物标志物响应综述性研究
Jonathan J Bjerre-Bastos,Nizar Hamrouni,Yves Henrotin et al.
Jonathan J Bjerre-Bastos et al.
Objective: Arthritic cartilage is primed for mechanical damage. Joint biochemical markers (JBM) could provide insight into the impact of mechanical stimulation on joint tissue turnover in osteoarthritis (OA) of potential ...
Current status of catabolic, anabolic and inflammatory biomarkers associated with structural and symptomatic changes in the chronic phase of post-traumatic knee osteoarthritis- a systematic review [0.03%]
与慢性期创伤后膝骨关节炎结构和症状变化相关的分解代谢、合成代谢及炎症生物标志物的现状-系统综述
Oliver O&#x;Sullivan,Peter Ladlow,Kat Steiner et al.
Oliver O&#x;Sullivan et al.
Post-traumatic OA (PTOA) can occur within 5 years after a significant injury and is a valuable paradigm for identifying biomarkers. This systematic review aims to summarise published literature in human studies on the associations of known ...
Virtual performance measure in osteoarthritis: An innovative transformation of patient care [0.03%]
虚拟性能指标在骨关节炎中的应用：一种患者护理的创新转型
Helen Razmjou,Suzanne Denis,Susan Robarts et al.
Helen Razmjou et al.
Objectives: The purpose of this study was to develop and establish reliability and validity of a virtual performance measure (VPM) score that encompassed 10 videos in patients with osteoarthritis of the knee joint. Patien...
Usage of guideline-adherent core treatments for knee osteoarthritis before and after consulting an orthopaedic surgeon: A prospective cohort study [0.03%]
关节镜手术前后膝骨关节炎患者指南推荐核心治疗的使用情况：前瞻性队列研究
Simon Majormoen Bruhn,Søren T Skou,Lasse Kindler Harris et al.
Simon Majormoen Bruhn et al.
Objective: To describe 1) the proportion of patients with knee osteoarthritis (OA) undergoing guideline-adherent core treatments until six months after primary referral to an orthopaedic surgeon, 2) which specific treatme...
The OARSI Joint Effort Initiative: Priorities for osteoarthritis management program implementation and research 2024-2028 [0.03%]
OARSI关节努力倡议：2024-2028年骨关节炎管理项目实施和研究的优先事项
Jocelyn L Bowden,David J Hunter,Kathryn Mills et al.
Jocelyn L Bowden et al.
Objective: The Joint Effort Initiative (JEI) is an international collaboration of clinicians, researchers, and consumer organisations with a shared vision of improving the implementation of osteoarthritis management progr...
Establishment of a uniform histological evaluation method for early stage osteophytes in the destabilization of the medial meniscus mouse model [0.03%]
构建内侧半月板不稳定小鼠模型早期骨赘形成的统一病理学评价方法
Akihiro Jono,Yuta Yanagihara,Tomofumi Kinoshita et al.
Akihiro Jono et al.
Background: Osteophyte formation is attracting attention as an early-stage pathology of knee osteoarthritis (OA). Although osteophyte formation is understood as a defense response to joint instability, its role and impact...
Our biology working against us in obesity: A narrative review on implications for management of osteoarthritis [0.03%]
肥胖发生时我们的生物学机制反而会起负面作用：对骨关节炎管理的启示综述性评论
Flavia M Cicuttini,Joseph Proietto,Yuan Z Lim
Flavia M Cicuttini
Obesity is the major modifiable risk factor for osteoarthritis (OA). A major focus of management in OA is weight loss. Although we live in an obesogenic environment, obesity has a predominantly genetic and epigenetic basis. This explains a ...