Epidemiology and treatment of pain associated with osteoarthritis of the knee in Germany: A retrospective health claims data analysis [0.03%]
德国膝骨关节炎相关疼痛的流行病学和治疗情况：一项回顾性健康索赔数据分析
Dominik Obermüller,Jörg Jerosch,Leonore Bovy et al.
Dominik Obermüller et al.
Objective: Osteoarthritis of the knee (knee OA) is a serious joint disease leading to pain and reduced quality of life. Pharmacological treatments include anti-inflammatories, analgesics, intraarticular hyaluronic acid, a...
COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study [0.03%]
COL11A1与发育性髋关节发育不良和奥斯陆研究中的继发性骨关节炎有关
Kaya Kvarme Jacobsen,Sigrid Børte,Lene Bjerke Laborie et al.
Kaya Kvarme Jacobsen et al.
Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30 % of all total hip arthroplasties (THAs) in adult...
"You don't put it down to arthritis": A qualitative study of the first symptoms recalled by individuals with knee osteoarthritis [0.03%]
《"你不会归咎于关节炎"：膝骨关节炎患者回忆起的最初症状的定性研究》
L K King,A Mahmoudian,E J Waugh et al.
L K King et al.
Objective: As part of the first phase of the OARSI Early-stage Symptomatic Knee Osteoarthritis (EsSKOA) initiative, we explored the first symptoms and experiences recalled by individuals with knee osteoarthritis (OA). ...
Pain-phenotyping in osteoarthritis: Current concepts, evidence, and considerations towards a comprehensive framework for assessment and treatment [0.03%]
骨关节炎中的疼痛分型：目前的概念、证据及评估和治疗的全面框架考虑因素
F Saxer,A Hollinger,M F Bjurström et al.
F Saxer et al.
Objectives: Pain as central symptom of osteoarthritis (OA) needs to be addressed as part of successful treatment. The assessment of pain as feature of disease or outcome in clinical practice and drug development remains a...
Investigation of the association of long-term NSAID use with radiographic hip osteoarthritis over four to five years: Data from the OAI and CHECK studies [0.03%]
长期服用非甾体抗炎药与四至五年放射学髋关节骨性关节炎的关联研究：OAI和CHECK研究数据
Zubeyir Salis
Zubeyir Salis
Objective: To examine the relationship between long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) and the incidence and progression of radiographic hip osteoarthritis (RHOA), as well as the degeneration of in...
The osteoarthritis prevention study (TOPS) - A randomized controlled trial of diet and exercise to prevent Knee Osteoarthritis: Design and rationale [0.03%]
骨关节炎预防研究（TOPS）-饮食和运动以防止膝骨关节炎的随机对照试验：设计与依据
Stephen P Messier,Leigh F Callahan,Elena Losina et al.
Stephen P Messier et al.
Background: Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities. The premise of this randomized clinical trial is that, in a population at risk, ...
Duloxetine plus exercise for knee osteoarthritis and depression: A feasibility study [0.03%]
关节炎和抑郁症的度洛西汀联合运动：一项可行性研究
Alan M Rathbun,Rhea Mehta,Alice S Ryan et al.
Alan M Rathbun et al.
Objective: To assess the feasibility of a 24-week, center-based, aerobic exercise program plus duloxetine to treat symptomatic knee osteoarthritis (OA) and major depression. ...
Serum proteomic panel validated for prediction of knee osteoarthritis progression [0.03%]
用于预测膝关节骨关节炎进展的血清蛋白组标志物_Panel验证研究
Virginia Byers Kraus,Alexander Reed,Erik J Soderblom et al.
Virginia Byers Kraus et al.
Objective: To further validate a serum proteomics panel for predicting radiographic (structural) knee OA progression. Design: Serum pep...
Imaging mass cytometry reveals tissue-specific cellular immune phenotypes in the mouse knee following ACL injury [0.03%]
基于质谱的成像揭示了ACL损伤后小鼠膝盖中的组织特异性免疫细胞表型
Sanique M South,M Caleb Marlin,Padmaja Mehta-D&#x;souza et al.
Sanique M South et al.
Objective: To develop an imaging mass cytometry method for identifying complex cell phenotypes, inter-cellular interactions, and population changes in the synovium and infrapatellar fat pad (IFP) of the mouse knee followi...
Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls [0.03%]
轻度关节退变和终末期骨关节炎人体半月板的蛋白质组分析
Rocío Paz-González,Aleksandra Turkiewicz,Neserin Ali et al.
Rocío Paz-González et al.
Objective: To gain new insight into the molecular changes of the meniscus by comparing the proteome profiles of healthy controls with mild degeneration and end-stage osteoarthritis (OA). ...