The infrapatellar fat pad mediates environmental exposure for clinical outcomes in knee osteoarthritis [0.03%]
髌下脂肪垫在膝骨关节炎临床症状中的环境介导作用
Anping Shen,Ruoyu Zhuang,Yan Xue et al.
Anping Shen et al.
Objective: This cross-sectional study aimed to investigate whether the infrapatellar fat pad (IPFP) mediates the relationship between environmental exposures and clinical symptoms in patients with knee osteoarthritis (KOA...
Investigating predictors of pain events during trials of knee osteoarthritis: A post-hoc analysis of two phase III trials [0.03%]
膝关节骨关节炎三期临床试验中疼痛事件的预测因素研究：事后分析
Andrea Bak Kaaber,Jakob Mejdahl Bentin,Ida Sofie Adrian et al.
Andrea Bak Kaaber et al.
Objective: This study aims to explore the associations between clinical characteristics, including medical history, and the frequency, severity, and type of pain events (PEs) over a two-year period in patients with knee o...
The severity of fatigue and its interplay with biological and psychological factors in people with hand osteoarthritis - Results from the Nor-Hand study [0.03%]
手骨关节炎患者疲劳的严重程度及其与生物学和心理学因素之间的相互作用——Nor-Hand研究的结果
Daniel H Bordvik,Marthe Gløersen,Elisabeth Mulrooney et al.
Daniel H Bordvik et al.
Background: Fatigue represents a concurrent yet uncommonly addressed symptom among people with hand osteoarthritis (OA). We aimed to explore fatigue severity and its interplay with other variables among hand OA patients. ...
The stability of pain phenotypes in people with hand osteoarthritis - results from the NOR-HAND study [0.03%]
手骨关节炎患者疼痛表型的稳定性——来自挪威NOR-HAND研究的结果
Daniel H Bordvik,Elisabeth Mulrooney,Pernille Steen Pettersen et al.
Daniel H Bordvik et al.
Objective: In a hand osteoarthritis (OA) cohort, we aimed to explore pain phenotypes and characterize their stabilities using the multidimensional framework developed by The Initiative on Methods, Measurement and Pain Ass...
High glucose upregulates BMAL1 in chondrocytes from macroscopically normal and osteoarthritic human cartilage but this only results in increased collagen synthesis in chondrocytes from macroscopically normal cartilage regions [0.03%]
高糖上调正常外观和骨关节炎人软骨中基质细胞核蛋白1（BMAL1）但仅在正常外观软骨区域的软骨细胞中增加胶原合成
Lekha Jain,Jacob T Munro,Jade Tamatea et al.
Lekha Jain et al.
Objective: Osteoarthritic (OA) chondrocytes exhibit limited capacity for new collagen synthesis. High glucose promotes collagen I and III production by fibroblasts. The purpose of this study was to determine if it also pr...
The role of metabolic syndrome in osteoarthritis development: Is obesity the key driver? [0.03%]
代谢综合征在骨关节炎发病中的作用：肥胖是关键驱动因素吗？
Dell&#x;Isola Andrea,Magnusson Karin,Vinblad Johanna et al.
Dell&#x;Isola Andrea et al.
Objective: Investigate the role of metabolic syndrome and obesity in incident osteoarthritis (OA). Methods: Prospective cohort study wi...
Tolerability of high intensity interval training (HIIT) in individuals living with knee OA and at risk for cardiovascular disease: A prospective cohort study (THIPO) [0.03%]
高膝骨关节炎伴心血管疾病风险个体进行高强度间歇训练(HIIT)的耐受性：前瞻性队列研究(THIPO)
Mathilde Espe Pedersen,Thomas Bandholm,Mathias Ried-Larsen et al.
Mathilde Espe Pedersen et al.
Objective: To explore the tolerability of a 12-week High Intensity Interval Training (HIIT) program in individuals with knee osteoarthritis (OA) at elevated risk for cardiovascular disease (CVD). ...
Studying the formation of the zone of calcified cartilage in bovine cartilage explants ex vivo [0.03%]
体外研究牛软骨移植物中钙化软骨区的形成
Jietao Xu,Andrea Schwab,Elias Salzer et al.
Jietao Xu et al.
Objective: The zone of calcified cartilage (ZCC) connects non-calcified articular cartilage to the subchondral bone, acting as transitional layer. Regeneration of this layer is key for cartilage repair but remains a chall...
Association between symptomatic knee osteoarthritis and health-related quality of life in individuals with type 2 diabetes: A cross-sectional study [0.03%]
II型糖尿病患者膝骨关节炎与健康相关生活质量的关系：横断面研究
Abdalmohsen Almodahka,Alanna Weisman,Baiju R Shah et al.
Abdalmohsen Almodahka et al.
Objective: Knee osteoarthritis (OA) and type 2 diabetes (T2D) commonly coexist, but their combined impact on health-related quality of life (HRQoL) remains understudied. We assessed the association between symptomatic kne...
Clinical characteristics and physical activity levels of patients with knee osteoarthritis with and without a previous knee injury: A cross-sectional study [0.03%]
有无膝关节既往损伤的膝骨关节炎患者的临床特征和身体活动水平：横断面研究
Richard E Magony,Jeffrey S Brooks,Jenna M Schulz et al.
Richard E Magony et al.
Objective: To compare clinical characteristics and physical activity levels of patients with mild-to-moderate knee osteoarthritis (OA). Methods: ...