Risk of all-cause mortality in patients with knee osteoarthritis: A systematic review and meta-analysis of cohort studies [0.03%]
膝骨关节炎患者全因死亡率的系统评价和meta分析
Pei-En Kao,Amy Ker
Pei-En Kao
Objective: This systematic review and meta-analysis aimed to evaluate the risk of all-cause mortality in patients with knee osteoarthritis (OA). Design: ...
Proteomic analysis reveals biomarkers associated with performance-based joint function and patient-reported outcomes in knee osteoarthritis [0.03%]
基于蛋白质组学分析发现膝关节骨关节炎患者功能表现及自我报告结果相关的生物标志物
Josefine E Naili,Aisha S Ahmed,Margareta Hedström et al.
Josefine E Naili et al.
Objective: This study aimed to identify proteins associated with clinical manifestations of knee osteoarthritis (KOA), including performance-based joint function and patient-reported outcome measures (PROM). ...
The collagenase-induced osteoarthritis (CIOA) model: Where mechanical damage meets inflammation [0.03%]
胶原酶诱导的骨关节炎(CIOA)模型：机械损伤与炎症相互作用的研究
Patrick Weber,Kajetana Bevc,David Fercher et al.
Patrick Weber et al.
Objective: To characterize inflammatory and mechanical changes in the collagenase-induced OA (CIOA) model in rats. Design: Skeletally m...
Peripheral arterial pathology and osteoarthritis of the knee: US examination of arterial wall stiffness, thickness, and flow characteristics [0.03%]
膝骨关节炎的外周动脉病理：关于动脉壁僵硬度、厚度和血流特征的超声检查
Jon Olansen,Minglang Yin,Janine Molino et al.
Jon Olansen et al.
Background: Osteoarthritis (OA) is a widespread chronic joint disorder characterized by the degeneration of articular cartilage, extensive bone remodeling, ligamentous fibrosis, and synovial inflammation impacting million...
An unsupervised online Tai Chi program for people with knee osteoarthritis ("My Joint Tai Chi"): Study protocol for the RETREAT randomised controlled trial [0.03%]
针对膝骨关节炎患者的无监督太极干预研究——随机对照RETREAT试验方案：“我的关节太极”项目
Shiyi Julia Zhu,Rachel K Nelligan,Rana S Hinman et al.
Shiyi Julia Zhu et al.
Background: Knee osteoarthritis (OA) is a leading contributor to global disability, with exercise proven to be an effective treatment. Tai Chi is a recommended type of exercise, but it is primarily done in person which im...
A phase III study to evaluate the long-term safety and efficacy of fasinumab in patients with pain due to osteoarthritis of the knee or hip [0.03%]
评价因膝关节或髋关节骨关节炎导致疼痛的患者中 farinumab 长期安全性和有效性的III期研究
Stephen J DiMartino,Jingning Mei,Thomas J Schnitzer et al.
Stephen J DiMartino et al.
Background: Pain associated with osteoarthritis (OA) is frequently disabling; treatments are often ineffective or intolerable. Fasinumab selectively inhibits nerve-growth factor and has shown efficacy for the management o...
Depression predicts decreased lumbar bone mineral density: A scoping review of chronic psychological stress and spinal tissue pathology [0.03%]
抑郁症可预测腰椎骨密度降低：慢性心理压力与脊柱组织病理损害的综述研究
Mary A Bucklin,Eric C Gehrke,Jennifer C Westrick et al.
Mary A Bucklin et al.
Objective: Chronic low back pain (cLBP) is a complex disease with biological, psychological, and social components and the complex interactions of these components are poorly understood. Chronic psychological stress (CPS)...
The association of spinal morning stiffness with lumbar disc degeneration and C-reactive protein: The back complaints in older adults (BACE) study [0.03%]
脊柱晨僵与腰椎间盘退变和C-反应蛋白的相关性：老年人背痛（BACE）研究
Daniel Feller,Roxanne van den Berg,Wendy T M Enthoven et al.
Daniel Feller et al.
Objective: To determine the association between patient-reported spinal morning stiffness and lumbar disc degeneration (LDD) and systemic inflammation, as measured by C-reactive protein (CRP), in older patients with non-s...
Association of cartilage [Formula: see text] and [Formula: see text] relaxation time measurement with hip osteoarthritis progression: A 5-year longitudinal study using voxel-based relaxometry and Z-score normalization [0.03%]
基于体素的弛豫时间和Z分数标准化评估软骨T2和T1ρ值与髋关节炎进展相关性五年纵向研究
Rafeek Thahakoya,Koren E Roach,Misung Han et al.
Rafeek Thahakoya et al.
Objective: To study the longitudinal changes of cartilage T 1 ρ and T 2 relaxation time measurements in hip-OA patients. Methods: ...
Bone marrow lesions in osteoarthritis: Characterising genetic and histological changes to understand disease pathophysiology [0.03%]
骨关节炎中的骨髓病变：表征遗传和组织学变化以了解疾病病理生理学
Nidhi Sofat,Franklyn Arron Howe
Nidhi Sofat
Osteoarthritis (OA) is a chronic debilitating condition that affects the whole joint. There are several sources of pain in OA that include the synovium, bone, including osteophytes and more recently bone marrow lesions (BML) that correlate ...