Imaging-based measures of synovitis in knee osteoarthritis: A scoping review and narrative synthesis [0.03%]
基于影像的膝骨关节炎滑膜炎检测方法：系统综述和叙述综合
Robert S Dima,Trevor B Birmingham,Mary-Ellen Empey et al.
Robert S Dima et al.
Background: Synovitis has emerged as a tissue target of importance in OA research and is commonly evaluated with medical imaging. Objectives: ...
Mark D Wishman,William M Sgrignoli,Brendan M Patterson et al.
Mark D Wishman et al.
Objective: This review explores periostin (POSTN), a matricellular protein integral to developmental physiological, and pathological processes, by examining its structure, function, and emerging roles in orthopedic and no...
Exploring associations among pro-inflammatory cytokines, osteoarthritis, and gut microbiome composition in individuals with obesity using machine learning [0.03%]
利用机器学习探索肥胖个体中促炎症细胞因子、骨关节炎和肠道微生物组组成的关联性
Cameron Kurz,Liubov Arbeeva,M Andrea Azcarate-Peril et al.
Cameron Kurz et al.
Objective: To investigate potentially novel and modifiable mechanisms of the effects of gut microbiome composition on obesity-related osteoarthritis (OA), focusing on cross-sectional relationships between microbiota, cyto...
Temporomandibular joint degeneration arises spontaneously in STR/ort mice and is prevented by targeted aggrecanase inhibition [0.03%]
靶向降解聚集素酶可阻止STR/ort小鼠发生颞下颌关节退变
Kazuhiro Ooi,Kazuhiro Yamamoto,Yutaka Kobayashi et al.
Kazuhiro Ooi et al.
Objective: Temporomandibular joint osteoarthritis (TMJ-OA) is painful and causes masticatory dysfunction, but current treatment is limited to symptom relief due to an incomplete appreciation of aetiology. Herein, we devel...
Changing the narrative for exercise-based prehabilitation: Evidence-informed and shared decision making when discussing the need for a total knee arthroplasty with patients [0.03%]
基于锻炼的术前康复的叙述变革：与患者讨论全膝关节置换必要性时采取循证和共同决策
Thomas Bandholm,Rasmus Skov Husted,Anders Troelsen et al.
Thomas Bandholm et al.
Objective: To examine a novel application of exercise-based prehabilitation in severe knee osteoarthritis-termed "pre-evaluation exercise"-focused on supporting surgical decision-making and adherence to clinical guideline...
Early age-related changes to articular cartilage T1ρ in hips with Legg-Calvé-Perthes disease deformity [0.03%]
腿腔氏病畸形髋关节软骨T1ρ早期年龄相关变化的研究
Luke G Johnson,Carly E Jones,Daniel G Rosenbaum et al.
Luke G Johnson et al.
Objective: To determine whether the relationship between cartilage T1ρ relaxation time and age during adolescence and young adulthood is different in hips with Legg-Calvé-Perthes disease (LCPD) deformity compared to hip...
Efficacy of intra-articular injections for the treatment of osteoarthritis: A narrative review [0.03%]
关节内注射治疗骨关节炎的有效性：一项叙述性综述
Sam Si-Hyeong Park,Biao Li,Christopher Kim
Sam Si-Hyeong Park
Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by progressive cartilage loss, inflammation, and joint dysfunction. With profound effects on joint function and quality of life, OA imposes a substantial socio-econ...
Presence of erosions is not a risk factor for the development of knee OA in a hand OA population: Results from the Framingham OA study [0.03%]
存在侵蚀不是手骨关节炎人群中膝骨关节炎发病的危险因素：弗雷明汉骨关节炎研究结果
T Vanhaverbeke,G Miller,N C Ukonu et al.
T Vanhaverbeke et al.
Objective: This study aimed to investigate whether there is a difference in risk of knee OA between individuals with erosive hand osteoarthritis (OA) compared to non-erosive hand OA, and to identify other risk factors for...
Immobilization by 21-days of bed rest causes changes in biomarkers of cartilage homeostasis in healthy individuals [0.03%]
21天卧床引起的健康个体软骨稳态生物标志物的变化
Maren Dreiner,Elie-Tino Godonou,Annegret Mündermann et al.
Maren Dreiner et al.
Objective: To investigate the effects of 21 days bed rest immobilization (with and without exercise and nutrition intervention) on serum concentrations of cartilage homeostasis biomarkers in healthy individuals. ...
Explanatory factors for the survival benefit among hip and knee arthroplasty patients with osteoarthritis [0.03%]
解释因髋膝关节成形术患者骨关节炎生存获益的因素
Jan M Heijdra Suasnabar,Maaike Gademan,Liza van Steenbergen et al.
Jan M Heijdra Suasnabar et al.
Objective: Studies have shown that osteoarthritis patients who underwent a primary total hip or knee arthroplasty (THA/TKA) experience better survival than the general population, yet there is limited evidence explaining ...