Effects of high impact exercise on systemic cytokines in women with mild knee osteoarthritis: A 12-month RCT [0.03%]
高强度冲击运动对轻度膝骨关节炎女性全身细胞因子的影响：一项为期12个月的随机对照试验
Ville-Markus Konola,Juhani Multanen,Johanna K Ihalainen et al.
Ville-Markus Konola et al.
Objective: This study investigated the effects of a high-impact exercise regimen compared with a reference group on systemic cytokine levels in patients with mild knee osteoarthritis (OA). Furthermore, associations betwee...
Stromal cell-based injection therapies for the treatment of knee osteoarthritis: A systematic review of level I randomized controlled trials [0.03%]
基于间质细胞的注射疗法治疗膝关节骨关节炎：1级随机对照试验系统评价
Jaydeep Dhillon,James A Maguire,Matthew J Kraeutler
Jaydeep Dhillon
Objective: To systematically review randomized controlled trials (RCTs) to compare clinical outcomes of stromal cell-based injection therapies versus other non-operative treatment modalities for the treatment of knee oste...
Extracellular vesicles in osteoarthritis synovial fluid contain both transmembrane and intravesical TNF-α [0.03%]
滑膜液外泌体包含TNF-α跨膜和囊内两种形式
Xin Zhang,Virginia Byers Kraus
Xin Zhang
Objective: We previously identified extracellular vesicles (EVs) as a key source of TNF-α in the plasma of both knee osteoarthritis (OA) patients and healthy individuals. Building on these findings, this study aimed to e...
KArAT (Knee Arthroplasty Activity Trial): Rationale and design features of a multicenter randomized controlled trial [0.03%]
单中心随机对照试验卡塔(T(Knee Arthroplasty Activity Trial):理论与设计特点
Elena Losina,Jamie E Collins,Mahima Kumara et al.
Elena Losina et al.
Background: Total knee arthroplasty (TKA) is commonly performed to relieve pain in persons with severe knee osteoarthritis. Despite substantial pain reduction and functional improvements, physical activity (PA) does not n...
Online osteoarthritis training programme for community-based clinicians: Mixed methods cohort study [0.03%]
针对社区医护人员的在线骨关节炎培训项目：混合方法队列研究
Ben Darlow,Melanie Brown,Alison Pask et al.
Ben Darlow et al.
Background: Core osteoarthritis interventions are ideally delivered in community-based settings. However, many community-based clinicians lack confidence and/or competence to effectively deliver high-quality, culturally-s...
Implementation of best-evidence rehabilitation for hip, knee and hand osteoarthritis in Africa: A cause for concern [0.03%]
非洲骨关节炎康复最佳证据的实施令人担忧：关于髋、膝和手骨关节炎的研究报告
Monique M Keller,Beatrice Sankah
Monique M Keller
Importance: Evidence-based practice recommendations and guidelines highlight the benefits of exercise, physical activity, weight management, and education for self-management, which are effective in the management of oste...
The effects of combining electrical stimulation of the calf and thigh muscles on WOMAC pain in knee osteoarthritis: A double-blind, randomised, sham-controlled trial [0.03%]
小腿和大腿肌肉电刺激联合运用对膝骨关节炎患者WOMAC疼痛评分影响的双盲随机对照试验
Samuel Briggs-Price,George Mills,Linzy Houchen-Wolloff et al.
Samuel Briggs-Price et al.
Objective: To explore the effectiveness of a NMES device in improving pain and function for individuals with KOA. Method: This was a ra...
Associations between obesity, physical and mental function, and low back pain intensity and disability: A 14-year population-based study [0.03%]
一项为期14年的基于人群的队列研究：肥胖与躯体及心理功能、慢性下腰痛强度和功能障碍的关系
Bothaina Alyousef,Flavia M Cicuttini,Yuanyuan Wang et al.
Bothaina Alyousef et al.
Objective: This study aimed to examine the associations of overweight/obesity, physical function and mental function with back pain intensity and disability. ...
Twelve-month efficacy of carboxymethyl-chitosan in refractory knee osteoarthritis: A randomized controlled trial (PIONEER) [0.03%]
卡波姆联合壳聚糖治疗膝骨关节炎1年疗效的随机对照研究(PIONEER)
Philippe Van Overschelde,Pieter Vansintjan,Nicolas Portelange et al.
Philippe Van Overschelde et al.
Objectives: The 12-month efficacy and safety of a novel bioresorbable fluid implant based on CM-chitosan for intra-articular injection was evaluated in knee osteoarthritis (OA) patients with predictive factors of failure ...
Features and management of osteoarthritis from the perspective of individuals with osteoarthritis: A systematic review of qualitative studies [0.03%]
从骨关节炎患者的角度看骨关节炎的特征和管理：定性研究的系统评价
Sylvain Mathieu,Alice Courties,Céline Mathy et al.
Sylvain Mathieu et al.
Objective: To enable person-centered care, considering beliefs, needs, and priorities of individuals with osteoarthritis (OA) is crucial. Nevertheless, concepts that they consider important are not fully recapitulated in ...