Microbiota-gut-brain axis in neurodegenerative diseases: molecular mechanisms and therapeutic targets [0.03%]
神经退行性疾病中的微生态-肠-脑轴:分子机制和治疗靶点
Ce Chen,Guo-Qing Wang,Dai-di Li et al.
Ce Chen et al.
The microbiota-gut-brain axis (MGBA) is an intricate bidirectional communication network that links intestinal microbiota with the central nervous system (CNS) through immune, neural, endocrine, and metabolic pathways. Emerging evidence sug...
Metformin modulates mitochondrial metabolism and epigenetic dysregulation in DNMT3A-mutated clones [0.03%]
二甲双胍可调节DNMT3A突变克隆的线粒体代谢和表观遗传失调
Xiaoyin Hu,Bin Wang,Long Zhang
Xiaoyin Hu
Dendritic cells: understanding ontogeny, subsets, functions, and their clinical applications [0.03%]
树突状细胞:理解发生、亚群、功能及其临床应用
Wenhao Li,Chenyu Yu,Xujian Zhang et al.
Wenhao Li et al.
Dendritic cells (DCs) play a central role in coordinating immune responses by linking innate and adaptive immunity through their exceptional antigen-presenting capabilities. Recent studies reveal that metabolic reprogramming-especially path...
Xiaoqin Xu,Tingting Zeng,Si Chen et al.
Xiaoqin Xu et al.
Acute kidney injury (AKI) is a prevalent clinical condition that is associated with unacceptably high morbidity and mortality, as well as the development of chronic kidney disease (CKD). The pathogenesis of AKI is highly complex and heterog...
Damage-associated molecular patterns (DAMPs) in diseases: implications for therapy [0.03%]
损伤相关分子模式(DAMPs)与疾病:治疗的潜在靶点
Heya Lin,Wei Xiong,Lili Fu et al.
Heya Lin et al.
Damage-associated molecular patterns (DAMPs) are endogenous danger signal molecules released by damaged, stressed or dead cells that bind to pattern recognition receptors (PRRs), activating immune responses and inflammatory signaling pathwa...
Luyao Zheng,Anqi Zeng,Li Liu et al.
Luyao Zheng et al.
Metabolic syndrome (MetS, MS) is a group of metabolic disorders characterized by central obesity, insulin resistance, dyslipidemia, and imbalance of glucose homeostasis. Studies have revealed that the molecular mechanism of MetS may be rela...
A new twist on lactate signaling: alanyl-tRNA synthetases 1 and 2 as metabolic sensors and lactyltransferases [0.03%]
丙氨酰-tRNA合成酶1和2作为代谢传感器和乳酰转移酶的新的乳酸信号机制研究
Ting Xiao,Fubing Wang,Xinghua Long
Ting Xiao
Mucosal immunity and vaccination strategies: current insights and future perspectives [0.03%]
黏膜免疫与疫苗策略:当前见解和未来展望
Zhihao Zhang,Weiqi Hong,Yu Zhang et al.
Zhihao Zhang et al.
The mucosal immune system represents a critical defense mechanism, safeguarding the body from an array of external pathogens. As the body's first line of immune protection, it plays an essential role in initiating both innate and adaptive i...
High sensitivity detection of Hepatitis B virus RNA based on 3D-DNA nanomachine and protein nanopore sensing [0.03%]
基于三维DNA纳米机器和蛋白纳米孔的高灵敏乙型肝炎病毒RNA检测技术研究
Shixin Yan,Chuipeng Kong,Jiazhe Cheng et al.
Shixin Yan et al.
Serum Hepatitis B virus (HBV) RNA serves as a non-invasive biomarker for monitoring chronic hepatitis B and guiding treatment decisions. However, current diagnostic tests relying on Reverse Transcription Quantitative Polymerase Chain Reacti...
Publisher Correction: Combined inhibition of protein kinase B and enhancer of zeste homolog 2: a novel strategy to induce triple-negative breast cancer cell death [0.03%]
出版更正:蛋白激酶B和同种二聚体多梳抑制蛋白EZH2的联合抑制:一种诱导三阴性乳腺癌细胞凋亡的新策略
Xinxiao Zhu,Yongqiang Wang,Long Zhang
Xinxiao Zhu
Published Erratum
Molecular biomedicine. 2025 Aug 8;6(1):56. DOI:10.1186/s43556-025-00302-6 2025