Author Correction: The bone marrow niche components are adversely affected in sepsis [0.03%]
作者更正：骨髓小生境组分在脓毒症中受到不利影响
Fan Yin,Han Qian,Caiwen Duan et al.
Fan Yin et al.
Published Erratum
Molecular biomedicine. 2025 Nov 4;6(1):96. DOI:10.1186/s43556-025-00304-4 2025
Longitudinal changes in the genetic and environmental influences on DNA methylation linked to obesity measures: a 5-year twin study [0.03%]
与肥胖指标相关的DNA甲基化纵向遗传和环境影响变化的五年双胞胎研究
Xuanming Hong,Ke Miao,Weihua Cao et al.
Xuanming Hong et al.
The reproducibility of obesity-related DNA methylation (DNAm) sites (CpGs) remains low across studies, and the underlying mechanisms involving genetic and environmental contributions require further investigation. In this study, we systemat...
Immunogenomic analysis of concurrent lung cancer and tuberculosis reveals distinct immune milieu [0.03%]
免疫组学分析同时发生的肺癌和结核病揭示了不同的免疫微环境
Xiaoling Xu,Chaohui Bao,Nathaniel Deboever et al.
Xiaoling Xu et al.
MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors [0.03%]
MITF调节胃肠道间质瘤的自噬和细胞外囊泡货物
Elizabeth Proaño-Pérez,Eva Serrano-Candelas,Mario Guerrero et al.
Elizabeth Proaño-Pérez et al.
The role of Microphthalmia-associated Transcription Factor (MITF) in gastrointestinal stromal tumors (GISTs) remains unclear, although previous studies suggest it contributes to tumor growth regulation. Previously, we demonstrated that MITF...
Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression [0.03%]
微波动力疗法通过靶向PTK2B调节STAT3介导的GPX4表达诱导结直肠癌铁死亡
Hui Zhou,Zijiang Zhang,Zhongtao Liu et al.
Hui Zhou et al.
Colorectal cancer (CRC) is a common malignant tumor of the digestive tract, and chemotherapy resistance along with adverse reactions during treatment present significant challenges in clinical practice. Therefore, there is an urgent need to...
ROS homeostasis in cell fate, pathophysiology, and therapeutic interventions [0.03%]
ROS稳态在细胞命运、病理生理和治疗干预中的作用
Yuan-Shen Chen,Hui-Xiang Tian,Ding-Chao Rong et al.
Yuan-Shen Chen et al.
Reactive oxygen species (ROS) homeostasis is an essential process that enables cells dynamically regulate their ROS levels, thereby ensuring survival and the execution of diverse physiological functions. ROS, a group of highly reactive mole...
Targeting ESM-1 inhibits spinal metastasis by disrupting tumor-endothelial adhesion [0.03%]
靶向ESM-1通过破坏肿瘤内皮粘附抑制脊髓转移
Seong Jun Kim,Wan-Kyu Ko,Daye Lee et al.
Seong Jun Kim et al.
Distinct survival, optimal combination strategy of immunotherapy, and immunophenotype in uncommon and 20ins EGFR-mut lung adenocarcinoma: a multi-center study [0.03%]
罕见及EGFR 20ins突变肺腺癌的生存、免疫治疗策略和免疫表型的多中心研究
Yiting Sun,Lei Xu,Chaoqiang Deng et al.
Yiting Sun et al.
The efficiency and optimal combination strategies of immune checkpoint inhibitors (ICI) in lung adenocarcinoma (LUAD) patients with epidermal growth factor receptor (EGFR) other mutations apart from 19del/L858R (classical), which account fo...
Multicenter Study
Molecular biomedicine. 2025 Oct 30;6(1):88. DOI:10.1186/s43556-025-00331-1 2025
Dihydroorotate dehydrogenase inhibition activates STING pathway and pyroptosis to enhance NK cell-dependent tumor immunotherapy [0.03%]
二氢乳清酸脱氢酶抑制激活STING途径和细胞焦亡可增强NK细胞依赖性肿瘤免疫治疗
Yongrui Hai,Ruizhuo Lin,Weike Liao et al.
Yongrui Hai et al.
Cancer cells rely heavily on de novo pyrimidine synthesis. Inhibiting pyrimidine metabolism directly suppresses tumor growth and fosters immune activation within the tumor microenvironment. Dihydroorotate dehydrogenase (DHODH) is a key enzy...
A new frontier in cancer therapy: Inositol-requiring enzyme 1 alpha (IRE1α) and taxane-induced pyroptosis [0.03%]
癌症治疗的新前沿：内质网应激传感器IRE1α和紫杉烷诱导的细胞焦亡
Tong Chen,Yirong Li,Xinghua Long
Tong Chen