Raaj S Mehta,Bharati D Kochar,Korey Kennelty et al.
Raaj S Mehta et al.
Polypharmacy is a major health issue for older adults. Entangled with several geriatric syndromes, including frailty, falls and cognitive decline, research focused on polypharmacy has been challenged by heterogeneity in its definition, conf...
Author Correction: Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer's disease [0.03%]
作者更正：支持通过计算重新定位布美他尼用于APOE4相关性阿尔茨海默病的实验和现实证据
Alice Taubes,Phil Nova,Kelly A Zalocusky et al.
Alice Taubes et al.
Published Erratum
Nature aging. 2021 Dec;1(12):1202. DOI:10.1038/s43587-021-00144-1 2021
Conferencing in 2022 [0.03%]
2022年的会议活动
Yuan Fu,Guojun Bu,Takahisa Kanekiyo et al.
Yuan Fu et al.
Microbiota-dependent increase in δ-valerobetaine alters neuronal function and is responsible for age-related cognitive decline [0.03%]
依赖微生物群的δ-戊二醇β-三甲铵增加可改变神经元功能并导致年龄相关的认知能力下降
Omar Mossad,Elisa Nent,Sabrina Woltemate et al.
Omar Mossad et al.
Understanding the physiological origins of age-related cognitive decline is of critical importance given the rising age of the world's population1. Previous work in animal models has established a strong link between cognitive performance a...
Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice [0.03%]
senolytic疫苗可改善异染性老化小鼠的正常和病理老化表型并延长其寿命
Masayoshi Suda,Ippei Shimizu,Goro Katsuumi et al.
Masayoshi Suda et al.
Elimination of senescent cells (senolysis) was recently reported to improve normal and pathological changes associated with aging in mice1,2. However, most senolytic agents inhibit antiapoptotic pathways3, raising the possibility of off-tar...
Emre Guney,Alejandro Athie
Emre Guney
K Lenhard Rudolph
K Lenhard Rudolph
Sara Ancel,Jerome N Feige
Sara Ancel
Longitudinal Aging Study in India (LASI): new data resources for addressing aging in India [0.03%]
印度生命周期研究（LASI）：解决印度老龄问题的新数据资源
David E Bloom,T V Sekher,Jinkook Lee
David E Bloom