Anna Kriebs
Anna Kriebs
A hematology-based clock derived from the Study of Longitudinal Aging in Mice to estimate biological age [0.03%]
基于小鼠纵向衰老研究的血细胞衍生的估算生物年龄的时钟
Jorge Martinez-Romero,Maria Emilia Fernandez,Michel Bernier et al.
Jorge Martinez-Romero et al.
Biological clocks and other molecular biomarkers of aging are difficult to implement widely in a clinical setting. In this study, we used routinely collected hematological markers to develop an aging clock to predict blood age and determine...
Philippe Saad
Philippe Saad
SEA-AD is a multimodal cellular atlas and resource for Alzheimer's disease [0.03%]
基于阿尔茨海默病的多模态细胞图谱和资源SEA-AD
Michael Hawrylycz,Eitan S Kaplan,Kyle J Travaglini et al.
Michael Hawrylycz et al.
The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) is a multifaceted open data resource designed to identify cellular and molecular pathologies that underlie Alzheimer’s disease. Integrating neuropathology, single cell and spatial ...
Evan D Shaulson,Alan A Cohen,Martin Picard
Evan D Shaulson
Aging involves seemingly paradoxical changes in energy metabolism. Molecular damage accumulation increases cellular energy expenditure, yet whole-body energy expenditure remains stable or decreases with age. We resolve this apparent contrad...
Hannah Walters
Hannah Walters
Dmitri Jdanov,Domantas Jasilionis
Dmitri Jdanov
Implausibility of radical life extension in humans in the twenty-first century [0.03%]
21世纪人类实现极端生命延长技术的不可能性
S Jay Olshansky,Bradley J Willcox,Lloyd Demetrius et al.
S Jay Olshansky et al.
Over the course of the twentieth century, human life expectancy at birth rose in high-income nations by approximately 30 years, largely driven by advances in public health and medicine. Mortality reduction was observed initially at an early...
Jean Nakhle
Jean Nakhle