Jessica C Hsu,Zhongmin Tang,Olga E Eremina et al.
Jessica C Hsu et al.
Medical imaging, which empowers the detection of physiological and pathological processes within living subjects, has a vital role in both preclinical and clinical diagnostics. Contrast agents are often needed to accompany anatomical data w...
Christine Grienberger,Andrea Giovannucci,William Zeiger et al.
Christine Grienberger et al.
In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal activity in the intact brain. It is based on the principle that, when neurons fire action potentials, intracellular calcium levels rise, which can be detec...
Gabriela Romero,Jimin Park,Florian Koehler et al.
Gabriela Romero et al.
Weak magnetic fields offer nearly lossless transmission of signals within biological tissue. Magnetic nanomaterials are capable of transducing magnetic fields into a range of biologically relevant signals in vitro and in vivo. These nanotra...
M C DeRosa,A Lin,P Mallikaratchy et al.
M C DeRosa et al.
The introduction of the in-vitro evolution method known as SELEX (Systematic Evolution of Ligands by Exponential enrichment) more than 30 years ago led to the conception of versatile synthetic receptors known as aptamers. Offering many bene...
Valentina Emiliani,Emilia Entcheva,Rainer Hedrich et al.
Valentina Emiliani et al.
Optogenetic techniques have been developed to allow control over the activity of selected cells within a highly heterogeneous tissue, using a combination of genetic engineering and light. Optogenetics employs natural and engineered photorec...
Atom probe tomography [0.03%]
原子探针层析术
Baptiste Gault,Ann Chiaramonti,Oana Cojocaru-Mirédin et al.
Baptiste Gault et al.
Atom probe tomography (APT) provides three-dimensional compositional mapping with sub-nanometre resolution. The sensitivity of APT is in the range of parts per million for all elements, including light elements such as hydrogen, carbon or l...
Paul Rees,Huw D Summers,Andrew Filby et al.
Paul Rees et al.
Imaging flow cytometry combines the high throughput nature of flow cytometry with the advantages of single cell image acquisition associated with microscopy. The measurement of large numbers of features from the resulting images provides ri...
Colinda L G J Scheele,David Herrmann,Erika Yamashita et al.
Colinda L G J Scheele et al.
Tissues are heterogeneous with respect to cellular and non-cellular components and in the dynamic interactions between these elements. To study the behaviour and fate of individual cells in these complex tissues, intravital microscopy (IVM)...
Ulrich Blache,Eden M Ford,Byunghang Ha et al.
Ulrich Blache et al.
Cells' local mechanical environment can be as important in guiding cellular responses as many well-characterized biochemical cues. Hydrogels that mimic the native extracellular matrix can provide these mechanical cues to encapsulated cells,...
Volume electron microscopy [0.03%]
体视学法
Christopher J Peddie,Christel Genoud,Anna Kreshuk et al.
Christopher J Peddie et al.
Life exists in three dimensions, but until the turn of the century most electron microscopy methods provided only 2D image data. Recently, electron microscopy techniques capable of delving deep into the structure of cells and tissues have e...