Ruihai Wang,Qianhao Zhao,Lars Loetgering et al.
Ruihai Wang et al.
Ptychography is a computational imaging technique that operates across multiple wavelength regimes, from electron (picometres) to X-ray (~0.1 nm), extreme ultraviolet (~10 nm), and visible light (micrometres). By reconstructing both amplitu...
Droplet-based bioprinting [0.03%]
基于微滴的生物打印技术
Deepak Gupta,Irem Deniz Derman,Changxue Xu et al.
Deepak Gupta et al.
Three-dimensional (3D) bioprinting facilitates the automated patterning of biological entities (such as cells and tissue building blocks) with or without scaffolding biomaterials. The technique enables fabrication of highly organized struct...
Lance A Liotta,Thomas P Conrads,Marissa A Howard et al.
Lance A Liotta et al.
The tissue microenvironment was once viewed as an impossibly complex heterogeneous ecosystem. Today, tools and data analysis methods probe tissues at multiple resolution levels, from subpopulations to individual cells and individual molecul...
Extracellular vesicle analysis [0.03%]
外泌体分析
An Hendrix,Lien Lippens,Cláudio Pinheiro et al.
An Hendrix et al.
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as extracellular vesicles (EVs), into their surroundings to enable intercellular communication. EVs have numerous functions in physiological and pathoph...
Nathaniel P Williams,Mihaly Voroslakos,Delin Shi et al.
Nathaniel P Williams et al.
Microelectrode arrays (MEAs) are devices capable of recording extracellular action potentials (spikes) from many neurons simultaneously and with high spatial and temporal resolution. MEAs have emerged as an invaluable tool for understanding...
Riccardo Levato,Oksana Dudaryeva,Carlos Ezio Garciamendez-Mijares et al.
Riccardo Levato et al.
Light-based vat-polymerization bioprinting enables computer-aided patterning of 3D cell-laden structures in a point-by-point, layer-by-layer or volumetric manner, using vat (vats) filled with photoactivatable bioresin (bioresins). This coll...
Julienne L Carstens,Santhoshi N Krishnan,Arvind Rao et al.
Julienne L Carstens et al.
Much like solving a game of Clue, understanding physiological mysteries involves answering who, what, when, and where. Multi-omics approaches delve into cellular and molecular identities (the who and what), while longitudinal data collectio...
Tianqi Yang,Siyuan Wang
Tianqi Yang
Correct organization of higher-order genome folding is essential for the regulation of gene expression, DNA replication and other genomic functions. Technological advances in high-throughput sequencing-based methods have allowed for systema...
Shuying Chen,Xiangang Huang,Yonger Xue et al.
Shuying Chen et al.
mRNA vaccines have emerged as a revolutionary tool to generate rapid and precise immune responses against infectious diseases and cancers. Compared with conventional vaccines such as inactivated viruses, viral vectors, protein subunits or D...
Shaopeng Liu,Judith S Rodriguez,Viorel Munteanu et al.
Shaopeng Liu et al.
Metagenomics has revolutionized our understanding of microbial communities, offering unprecedented insights into their genetic and functional diversity across Earth's diverse ecosystems. Beyond their roles as environmental constituents, mic...