Emily B Derrick,Paul A Beavis
Emily B Derrick
Dalpiciclib plus endocrine therapy in women with HR+/HER2- advanced breast cancer and visceral crisis: a multicenter, nonrandomized, phase 2 DARVIN trial [0.03%]
用于治疗激素受体阳性/HER2阴性晚期乳腺癌合并脏器危象女性患者的方法：达尔芬二期临床试验中多中心非随机Dalpiciclib联合内分泌治疗的研究
Hongnan Mo,Yuee Teng,Li Cai et al.
Hongnan Mo et al.
Visceral crisis in advanced breast cancer (ABC) represents a major challenge. Here we conducted a phase 2 study to evaluate dalpiciclib plus endocrine therapy (ET) in women with HR+/HER2- ABC experiencing visceral crisis. The primary endpoi...
Androgen loss contributes to neuroinflammation and promotes brain tumor growth [0.03%]
雄激素丢失促炎性细胞因子的产生并促进脑肿瘤生长
Heathcliff Dorado García
Heathcliff Dorado García
Author Correction: Disrupting the phase separation of KAT8-IRF1 diminishes PD-L1 expression and promotes antitumor immunity [0.03%]
作者更正：破坏KAT8-IRF1相分离可降低PD-L1表达并促进抗肿瘤免疫反应
Yuanzhong Wu,Liwen Zhou,Yezi Zou et al.
Yuanzhong Wu et al.
Published Erratum
Nature cancer. 2026 Jul 16. DOI:10.1038/s43018-026-01218-y 2026
Leukemic and normal hematopoietic stemness is influenced by transposable elements [0.03%]
转座子影响白血病和正常造血干性
Ioanna Pavlaki
Ioanna Pavlaki
Heathcliff Dorado García
Heathcliff Dorado García
Remi Hatinguais,Stan Verjans,Joana Gomes et al.
Remi Hatinguais et al.
Aberrant glycosylation is a nearly universal hallmark of cancer cells. Tumor-associated glycans can reshape cancer cell biology and act as crucial suppressors of anti-tumor immunity. By engaging immune inhibitory receptors or by modifying t...
PAPOLA-mediated hyperactive polyadenylation promotes leukemogenesis and leukemia stem cell self-renewal through metabolic reprogramming [0.03%]
PAPOLA介导的过度多聚腺苷酸化通过代谢重编程促进白血病发生和白血病干细胞自我更新
Siyao Guo,Yutong Zou,Canfeng Zhang et al.
Siyao Guo et al.
Polyadenylation is essential for mRNA stability and translational efficiency. Although poly(A) tail length is dynamically regulated under physiological conditions, its dysregulation and functional importance in cancer remain poorly understo...
Animesh Kar,Daniel Herranz
Animesh Kar