A nanobody-based degron system for targeted protein knockdown in Dictyostelium discoideum [0.03%]
基于纳米抗体的降解系统在Dictyostelium discoideum中的靶向蛋白敲低中的应用
Hidenori Hashimura,Shoko Fujishiro,Nao Shimada et al.
Hidenori Hashimura et al.
Backgrounds: The cellular slime mold Dictyostelium discoideum is a widely used model system for studying basic processes in cell and developmental biology. While genetic tools, such as targeted gene disruption by homologo...
Insulin signaling engages divergent transcriptional mechanisms in neural and metabolic tissues [0.03%]
胰岛素信号通过不同的转录机制调控神经组织和代谢组织中的基因表达
Roshni Jain,Rutuj Kolhe,Cassandra Hui et al.
Roshni Jain et al.
Human urine-derived stem exosomes inhibit inflammation and oxidative stress in sepsis-related acute kidney injury [0.03%]
人尿源性干细胞外泌体抑制脓毒症相关急性肾损伤的炎症和氧化应激
Lulu Liu,Lili Ding,Zhaorui Sun et al.
Lulu Liu et al.
Objective: The objective of this study was to explore the mechanisms by which urine - derived stem cell exosomes (USCexo) alleviate sepsis - related acute kidney injury (SAKI), as acute kidney injury often complicates sep...
Dose-dependent effects of atorvastatin on inflammatory response in endothelial cells: MMP/TIMP balance and in vitro wound closure assay [0.03%]
阿托伐他汀剂量依赖性对内皮细胞炎性反应的影响：基质金属蛋白酶／组织抑制剂平衡及体外伤口愈合试验评估
Betül İşiner,Aslı Fahriye Ceylan,Büşra Görgün et al.
Betül İşiner et al.
Background: Clinical and preclinical evidence suggests that inflammation is closely associated with various arterial diseases. Multiple studies have reported the effects of statins on different cell types, yet the effects...
Effects of prey quality through the life cycle of the social amoeba Dictyostelium discoideum [0.03%]
优质猎物对于Dictyostelium discoideum生活史的影响
Heng Liang,Margaret I Steele,Kaifeng Hu et al.
Heng Liang et al.
Genetic suppressor of autophagy defects in huntingtin null cells identified using a mutagenesis screen in Dictyostelium discoideum [0.03%]
利用Dictyostelium discoideum 筛选寻找亨廷顿基因缺失细胞自噬缺陷的遗传抑制因子
Lauren Cuoco,Shelbi E Gill,Luc Francois et al.
Lauren Cuoco et al.
Background: Huntingtin (HTT) is an important gene for cellular processes such as autophagy, and its loss leads to neurodegenerative disease phenotypes. In Dictyostelium discoideum, HTT-null (htt-) cells exhibit impaired b...
The Wnt/β-catenin pathway maintains homeostasis of amniocytes in Down syndrome [0.03%]
唐氏综合症患者绒毛外胚层细胞稳态的维持涉及Wnt/β-catenin信号通路
Xiaoying Chen,Miaochun Lin,Shan Chen et al.
Xiaoying Chen et al.
Isolation and characterization of mesenchymal stem cells from nasal polyps and olfactory mucosa: a comparative analysis of proliferation and multi-lineage differentiation capacity [0.03%]
人鼻息肉和嗅粘膜间充质干细胞的分离鉴定及其增殖和多向分化潜能的比较研究
Negin Khosravi,Zahra Pourmohammadi-Bejarpasi,Mehryar Habibi Roudkenar et al.
Negin Khosravi et al.
Effects of irisin on inflammatory and apoptotic markers in the Caco-2 colon cancer cell line [0.03%]
irisin对Caco-2结肠癌细胞系炎症和凋亡标志物的影响
Elif Zeynep Ozturk,Ebubekir Bakan,Nurcan Kilic Baygutalp et al.
Elif Zeynep Ozturk et al.
Intracellular Ca2+ is not essential for SHH signaling but is promoted by Shh ligand in embryonic fibroblasts [0.03%]
SHH信号传导不需要胞内钙离子，但SHH配体能促进胚胎成纤维细胞中的钙离子水平升高
Xuanming Shi,Zhaomin Wang,Shupeng Li et al.
Xuanming Shi et al.