Therapeutic drug monitoring of immunotherapies with novel Affimer-NanoBiT sensor construct [0.03%]
具有新型Affimer-NanoBiT传感器结构的免疫疗法治疗药物监测
Emma Campbell,Hope Adamson,Timothy Luxton et al.
Emma Campbell et al.
Concentration-therapeutic efficacy relationships have been observed for several therapeutic monoclonal antibodies (TmAb), where low circulating levels can result in ineffective treatment and high concentrations can cause adverse reactions. ...
Rapid fingerprinting of bacterial species using nanocavities created on screen-printed electrodes modified by β-cyclodextrin [0.03%]
基于β环糊精修饰的屏印电极纳米腔快速鉴别细菌种类
Niloofar Haghighian,Ritu Kataky
Niloofar Haghighian
Rapid and precise identification of infectious microorganisms is important across a range of applications where microbial contamination can cause serious issues ranging from microbial resistance to corrosion. In this paper a screen-printed,...
Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter measurement of global haemostasis [0.03%]
一种新的测量全球止血的定量多参数技术：垂直微流控条中流动液体的时空机器人成像技术
Rüya Meltem Sarıyer,Kirandeep Gill,Sarah H Needs et al.
Rüya Meltem Sarıyer et al.
Measuring the complex processes of blood coagulation, haemostasis and thrombosis that are central to cardiovascular health and disease typically requires a choice between high-resolution low-throughput laboratory assays, or simpler less qua...
From the lab to the field: handheld surface enhanced Raman spectroscopy (SERS) detection of viral proteins [0.03%]
从实验室到现场：手持表面增强拉曼光谱(SERS)检测病毒蛋白
Taylor D Payne,Stephen J Klawa,Tengyue Jian et al.
Taylor D Payne et al.
Translating sensors from the lab benchtop to a readily available point-of-need setting is desirable for many fields, including medicine, agriculture, and industry. However, this transition generally suffers from loss of sensitivity, high ba...
Point-of-care therapeutic drug monitoring of tumour necrosis factor-α inhibitors using a single step immunoassay [0.03%]
采用一步免疫测定法进行肿瘤坏死因子-α抑制剂治疗药物监测床旁检测
Eva A van Aalen,Ivar R de Vries,Eva T L Hanckmann et al.
Eva A van Aalen et al.
Therapeutic drug monitoring (TDM) of tumor necrosis factor-α (TNFα)-inhibitors adalimumab and infliximab is important to establish optimal drug dose and maximize treatment efficacy. Currently, TDM is primarily performed with ELISA techniq...
A novel point-of-care diagnostic prototype system for the simultaneous electrochemiluminescent sensing of multiple traumatic brain injury biomarkers [0.03%]
一种新颖的即时检测原型系统可同时电化学发光测定多种创伤性脑损伤生物标志物
Milica Jović,Denis Prim,Ophélie Righini et al.
Milica Jović et al.
Traumatic brain injuries (TBI) are typically acquired when a sudden violent event causes damage to the brain tissue. A high percentage (70-85%) of all TBI patients are suffering from mild TBI (mTBI), which is often difficult to detect and d...
Handheld device quantifies breath acetone for real-life metabolic health monitoring [0.03%]
手持式设备量化呼出气醋酮用于现实生活中的代谢健康监测
Grégoire M G B H Bastide,Anna L Remund,Dina N Oosthuizen et al.
Grégoire M G B H Bastide et al.
Non-invasive breath analysis with mobile health devices bears tremendous potential to guide therapeutic treatment and personalize lifestyle changes. Of particular interest is the breath volatile acetone, a biomarker for fat burning, that co...
Moving microcapillary antibiotic susceptibility testing (mcAST) towards the clinic: unravelling kinetics of detection of uropathogenic E. coli, mass-manufacturing and usability for detection of urinary tract infections in human urine [0.03%]
微毛细管抗生素敏感性试验（mcAST）向临床转化：解构尿源性致病大肠杆菌的检测动力学、大规模生产和人尿标本中泌尿道感染检测的使用性
Sarah H Needs,Jeremy Pivetal,Jessica Hayward et al.
Sarah H Needs et al.
Innovation in infection based point-of-care (PoC) diagnostics is vital to avoid unnecessary use of antibiotics and the development of antimicrobial resistance. Several groups including our research team have in recent years successfully min...
Single-channel digital LAMP multiplexing using amplification curve analysis [0.03%]
基于扩增曲线分析的单管数字LAMP多重检测方法
Kenny Malpartida-Cardenas,Luca Miglietta,Tianyi Peng et al.
Kenny Malpartida-Cardenas et al.
Loop-mediated isothermal amplification assays are currently limited to one target per reaction in the absence of melting curve analysis, molecular probes or restriction enzyme digestion. Here, we demonstrate multiplexing of five targets in ...
Correction: An amplification-free, 16S rRNA test for Neisseria gonorrhoeae in urine [0.03%]
关于奈瑟氏淋球菌尿液检测的更正：一种无需扩增的16S rRNA试验
Zhenrong Zheng,Yan Cao,Sukantha Chandrasekaran et al.
Zhenrong Zheng et al.
[This corrects the article DOI: 10.1039/D2SD00128D.]. This journal is © The Royal Society of Chemistry.
Published Erratum
Sensors & diagnostics. 2023 Jan 30;2(2):468. DOI:10.1039/d3sd90005c 2023