Biophysical characterization of sp Cas9 binding and cleavage using real-time electronic biosensors [0.03%]
Deependra Kumar Ban,Kshama Parate,Deepta Bharadwaj et al.
Deependra Kumar Ban et al.
CRISPR-Cas9 enables curative genome editing but requires precise control of target recognition, particularly when single-nucleotide polymorphisms (SNPs) influence specificity. Conventional biochemical and optical assays often rely on endpoi...
A new sequential dual flow lab-on-a-chip with a lyophilized one-component chemiluminescence substrate for high-sensitive microchannel lateral flow assay (mLFA) [0.03%]
一种新型的顺序双流实验室芯片，采用冻干的一组分化学发光底物，用于高灵敏微通道层析检测
Supreeth Setty,Heeyeong Jang,Jungyoup Han et al.
Supreeth Setty et al.
Recently, there has been a growing demand for the development of lab-on-a-chip (LOC) platforms with new assays and detection protocols for point-of-care-test (POCT) applications. So far, chemiluminescence (CL) detection-based immunoassays h...
Correction: High resolution voltammetric and field-effect transistor readout of carbon fiber microelectrode biosensors [0.03%]
订正：碳纤维微电极生物传感器的伏安法和场效应晶体管读取技术实现高分辨率检测
Whirang Cho,Harmain Rafi,Seulki Cho et al.
Whirang Cho et al.
[This corrects the article DOI: 10.1039/D2SD00023G.]. This journal is © The Royal Society of Chemistry.
Published Erratum
Sensors & diagnostics. 2025 Dec 9. DOI:10.1039/d5sd90047f 2025
Correction: Turn-on fluorescent sensors for Cu-rich amyloid β peptide aggregates [0.03%]
纠正：Cu丰富淀粉样蛋白β肽聚集体的开启型荧光传感器
Yiran Huang,Liang Sun,Liviu M Mirica
Yiran Huang
[This corrects the article DOI: 10.1039/D2SD00028H.]. This journal is © The Royal Society of Chemistry.
Published Erratum
Sensors & diagnostics. 2025 Dec 9. DOI:10.1039/d5sd90046h 2025
Species-specific discrimination of bacterial biofilms using a ratiometric fluorescence sensor array and machine learning [0.03%]
基于比例荧光传感器阵列和机器学习的细菌菌膜物种鉴别技术
Ritika Gupta,Aayushi Laliwala,Elena Muldiiarova et al.
Ritika Gupta et al.
Biofilms are intricate bacterial communities encased in a self-produced extracellular matrix (ECM) of DNA, lipids, proteins, and polysaccharides. The diverse ECM composition across bacterial species significantly influences the progression ...
Artificial intelligence-powered signal analysis of loop-mediated isothermal amplification (LAMP) for the screening of Kaposi sarcoma at the point of care [0.03%]
基于人工智能的信号分析技术在即时检测中筛查卡波西肉瘤分子标志物的研究
Darke Hull,Juan Boza,Jason Manning et al.
Darke Hull et al.
Unlike the polymerase chain reaction (PCR), loop-mediated isothermal amplification (LAMP) lacks a consistent thermal cycle, making quantification particularly challenging. Previously, we demonstrated that LAMP can accurately diagnose Kaposi...
A nucleic acid-based electrochemical detection method for post hoc sample analysis [0.03%]
一种基于核酸的电化学生物检测方法用于事后样本分析
Logan T Echeveria,Sadi Shahriar,Allison M Yorita et al.
Logan T Echeveria et al.
This work introduces a new electrochemical sensing approach, where the liquid sample containing nucleic acid targets can be blotted onto an electrode that is pre-functionalized with probe DNA. The post-hybridization signal and probe DNA sig...
Adapting antibody-invertase fusion protein immunoassays to multiwell plates for infectious disease antibody quantification [0.03%]
抗体-转化酶融合蛋白免疫测定在多孔板上的适应性研究用于传染病抗体定量分析
Elysse Ornelas-Gatdula,Xinran An,Jamie B Spangler et al.
Elysse Ornelas-Gatdula et al.
Traditional enzyme-linked immunosorbent assays (ELISAs) rely on horseradish peroxidase (HRP)-conjugated antibodies to generate a colorimetric response proportional to target antibody concentration. However, spectrophotometric quantification...
A near-infrared fluorescent aptananosensor enables selective detection of the stress hormone cortisol in artificial cerebrospinal fluid [0.03%]
一种近红外荧光适配子纳米传感器能够在人工脑脊液中选择性检测压力激素皮质醇
Jessica Kretli Zanetti,Maria Celina Stefoni,Catarina Ferraz et al.
Jessica Kretli Zanetti et al.
Cortisol is a hormone which regulates the body's response to stressors. Detection and monitoring of cortisol levels can provide information about physical and psychological health, thus it is essential to develop a sensor that can detect it...
Development of a selective-iodide indicator for live-cell imaging and evaluation of CFTR activity [0.03%]
一种用于活细胞成像和评估CFTR活性的选择性碘化物指示剂的发展
Jared Morse,Prasanna Ganesh,Kathrine Cowart et al.
Jared Morse et al.
Cystic fibrosis (CF) arises from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Monitoring I- transport serves as a critical approach for evaluating CFTR function in live cells, providing a foundation for ...