DISCO-LAMP: a novel discontinuous LAMP assay for isothermal antigen detection [0.03%]
用于等温抗原检测的新型断续环介导恒温扩增法（DISCO-LAMP）
Benjamin M Thomas,Rudo A Simeon,Katherine L Yan et al.
Benjamin M Thomas et al.
Proximity ligation assay (PLA) is a highly sensitive protein detection method in which DNA probes conjugated to affinity reagents are brought into proximity upon binding the same target molecule, thereby enabling greatly accelerated ligatio...
PEG-mediated viscous crowding controls dynamics and quantitative range in recombinase polymerase amplification nucleation site analysis [0.03%]
PEG介导的黏度拥挤调控重组酶聚合酶放大核位点分析的动力学和定量范围
Coleman D Martin,Nandini S Gummalla,Kelli N Shimazu et al.
Coleman D Martin et al.
Quantitative nucleic acid amplification tests (NAATs), such as qPCR or digital PCR, are essential diagnostic tools in the fields of medicine, environmental monitoring, and food safety. Recent efforts to bring nucleic acid quantification to ...
Translational opportunities in aptamer and nanobody lateral flow assays within the WHO REASSURED framework [0.03%]
世界卫生组织REASSURED框架中用于核算 lateral flow 试验的适配体和纳米抗体的机会
Evan T Monk,Erin M McConnell,David R McMullin et al.
Evan T Monk et al.
The World Health Organization's REASSURED framework underscores the role of lateral flow assays (LFAs) in addressing diagnostic access gaps in low-resource regions affected by emerging and re-emerging pathogens, neglected tropical diseases,...
Comparison of voltammetric methods used in the interrogation of electrochemical aptamer-based sensors [0.03%]
电化学适配子传感器的伏安法测定方法比较研究进展
Elsi Verrinder,Kaylyn K Leung,Murat Kaan Erdal et al.
Elsi Verrinder et al.
Electrochemical aptamer-based (EAB) sensors are the first continuous molecular measurement technology that is both (1) able to function in situ in the living body and (2) independent of the chemical reactivity of its targets, rendering it g...
Biophysical characterization of sp Cas9 binding and cleavage using real-time electronic biosensors [0.03%]
基于实时电子生物传感器的SpCas9结合及切割生化物理表征研究
Deependra Kumar Ban,Kshama Parate,Deepta Bharadwaj et al.
Deependra Kumar Ban et al.
CRISPR-Cas9 enables curative genome editing but requires precise control of target recognition, particularly when single-nucleotide polymorphisms (SNPs) influence specificity. Conventional biochemical and optical assays often rely on endpoi...
A new sequential dual flow lab-on-a-chip with a lyophilized one-component chemiluminescence substrate for high-sensitive microchannel lateral flow assay (mLFA) [0.03%]
一种新型的顺序双流实验室芯片，采用冻干的一组分化学发光底物，用于高灵敏微通道层析检测
Supreeth Setty,Heeyeong Jang,Jungyoup Han et al.
Supreeth Setty et al.
Recently, there has been a growing demand for the development of lab-on-a-chip (LOC) platforms with new assays and detection protocols for point-of-care-test (POCT) applications. So far, chemiluminescence (CL) detection-based immunoassays h...
Correction: High resolution voltammetric and field-effect transistor readout of carbon fiber microelectrode biosensors [0.03%]
订正：碳纤维微电极生物传感器的伏安法和场效应晶体管读取技术实现高分辨率检测
Whirang Cho,Harmain Rafi,Seulki Cho et al.
Whirang Cho et al.
[This corrects the article DOI: 10.1039/D2SD00023G.]. This journal is © The Royal Society of Chemistry.
Published Erratum
Sensors & diagnostics. 2025 Dec 9. DOI:10.1039/d5sd90047f 2025
Correction: Turn-on fluorescent sensors for Cu-rich amyloid β peptide aggregates [0.03%]
纠正：Cu丰富淀粉样蛋白β肽聚集体的开启型荧光传感器
Yiran Huang,Liang Sun,Liviu M Mirica
Yiran Huang
[This corrects the article DOI: 10.1039/D2SD00028H.]. This journal is © The Royal Society of Chemistry.
Published Erratum
Sensors & diagnostics. 2025 Dec 9. DOI:10.1039/d5sd90046h 2025
Species-specific discrimination of bacterial biofilms using a ratiometric fluorescence sensor array and machine learning [0.03%]
基于比例荧光传感器阵列和机器学习的细菌菌膜物种鉴别技术
Ritika Gupta,Aayushi Laliwala,Elena Muldiiarova et al.
Ritika Gupta et al.
Biofilms are intricate bacterial communities encased in a self-produced extracellular matrix (ECM) of DNA, lipids, proteins, and polysaccharides. The diverse ECM composition across bacterial species significantly influences the progression ...
Artificial intelligence-powered signal analysis of loop-mediated isothermal amplification (LAMP) for the screening of Kaposi sarcoma at the point of care [0.03%]
基于人工智能的信号分析技术在即时检测中筛查卡波西肉瘤分子标志物的研究
Darke Hull,Juan Boza,Jason Manning et al.
Darke Hull et al.
Unlike the polymerase chain reaction (PCR), loop-mediated isothermal amplification (LAMP) lacks a consistent thermal cycle, making quantification particularly challenging. Previously, we demonstrated that LAMP can accurately diagnose Kaposi...