Risk of bowel ischemia in patients with mesenteric neuroendocrine tumors after treatment with 177Lu-DOTATATE [0.03%]
177Lu-DOTATATE治疗肠系膜神经内分泌肿瘤后的肠道缺血风险
Eleonora Pelle,Taymeyah Al-Toubah,Ghassan El-Haddad et al.
Eleonora Pelle et al.
Background: Lutetium-177 (177Lu)-DOTATATE is an effective treatment for metastatic gastroenteropancreatic (GEP) NETs. However, radiation can cause transient inflammation/swelling of tumors, which can result in toxicity. T...
SIADH as an uncommon presentation of olfactory neuroblastoma: a case-based overview [0.03%]
嗅神经母细胞瘤导致SIADH的罕见病例及综述
Solene Papart,Adrian F Daly,Elettra Bianchi et al.
Solene Papart et al.
Background: Olfactory neuroblastoma (ONB) is a rare malignant neuroectodermal tumour that usually arises in the nasal cavity, typically presenting with unilateral nasal obstruction and epistaxis. In rare instances, ONB ca...
Thieno[2,3- b]pyridine compounds potently inhibit prostate cancer growth and motility [0.03%]
噻唑并吡啶化合物可有效抑制前列腺癌生长和运动能力
M A Alkheilewi,D A Leach,A Mohr et al.
M A Alkheilewi et al.
Objective: Prostate cancer growth is dependent upon androgens and hence therapies often target this signalling axis. These therapies, for example the antiandrogen enzalutamide, are successful in the majority of men; howev...
Prevalence of growth hormone deficiency in brain tumor survivors: a systematic review and meta-analysis [0.03%]
脑肿瘤幸存者中生长激素缺乏症患病率的系统评价和meta分析
Tatiana Tselovalnikova,Ben Ponvilawan,Maria G Pavlova et al.
Tatiana Tselovalnikova et al.
Objective: To evaluate the prevalence of growth hormone deficiency in patients who underwent cranial irradiation for brain tumors. Methods: ...
Using routinely collected patient data to study the impact of type 2 diabetes on breast cancer [0.03%]
利用常规收集的病人数据研究2型糖尿病对乳腺癌的影响
Ayaan Khurshed,Gema Hernandez,Gavin Soady et al.
Ayaan Khurshed et al.
Objective: Type 2 diabetes mellitus (T2DM) and cancer are prevalent conditions, with evidence linking T2DM to higher breast cancer incidence and mortality. However, it is uncertain whether excess mortality in breast cance...
Adrenal crisis due to pembrolizumab-induced hypophysitis in a patient with triple-negative breast cancer [0.03%]
派姆单抗引起的垂体炎导致的肾上腺危象一名三阴性乳腺癌患者案例
Sobrina S Mohammed,Sallam Alrosan,Reda Asad
Sobrina S Mohammed
We report a case of a 43-year-old woman with stage IIB triple-negative breast cancer (TNBC) on neoadjuvant pembrolizumab presenting in adrenal crisis. Biochemical evaluation revealed isolated adrenocorticotropic hormone (ACTH) deficiency, a...
Real-world lenvatinib use in metastatic thyroid cancer: early dose intensity and side effect profile in an Australian centre [0.03%]
雷那利姆ab治疗转移性甲状腺癌的真实世界研究：澳大利亚一中心的早期剂量强度和副作用谱型研究
Monica Majumder,Shejil Kumar,Tony Lian et al.
Monica Majumder et al.
Objective: Lenvatinib is a multi-kinase inhibitor approved in radioiodine-refractory thyroid cancer based on results of a phase III trial. Real-world data have emphasised concerns regarding tolerability of the starting do...
Radioembolization for neuroendocrine tumors: procedure, application and clinical outcomes [0.03%]
神经内分泌肿瘤的放射栓塞治疗：过程、应用及临床疗效
Li Shen Ho,Tarik Baetens,Marnix G E H Lam et al.
Li Shen Ho et al.
Neuroendocrine liver metastases significantly affect patient prognosis and quality of life due to their symptomatic burden and challenging management. Besides conventional systemic therapies, liver-directed therapies improve patient outcome...
Malignant transformation of parathyromatosis to parathyroid carcinoma with invasive growth and distant metastasis [0.03%]
甲状旁腺瘤恶变致侵袭性生长及远处转移的甲状旁腺癌一例报告
Chittari Venkata Harinarayan,Anugnya Premdas Ranjoalkar,Anisha Sawkar Tandon et al.
Chittari Venkata Harinarayan et al.
Parathyroid carcinoma (PC) is a rare endocrine malignancy. It accounts for about 1% of all primary hyperparathyroidism (PHPT) cases and 0.005% of all malignancies. PC presents with severe hypercalcemia, often refractory to standard medical ...
Vincent Cascio,W Reed Doerfler,Charit Taneja
Vincent Cascio
The brain is an uncommon location for metastatic spread from thyroid cancer. Given the rarity of the condition, the data regarding various management options for such patients are suboptimal. Radioactive iodine is seldom useful for brain me...