Lobectomy and completion thyroidectomy rates increase after the 2015 American Thyroid Association Differentiated Thyroid Cancer Guidelines update [0.03%]
2015年美国甲状腺协会分化型甲状腺癌指南更新后的肺叶切除术和次全甲状腺切除术率增加
Benjamin J Worrall,Alexander Papachristos,Ahmad Aniss et al.
Benjamin J Worrall et al.
Background: The 2015 American Thyroid Association (ATA) Guidelines permit thyroid lobectomy (TL) or total thyroidectomy in the management of low-risk papillary thyroid cancer (PTC). As definitive risk-stratification is on...
Cabergoline-associated valvulopathy of the tricuspid valve in the treatment of prolactinoma [0.03%]
卡麦角林治疗泌乳素瘤相关的三尖瓣瓣膜病病理生理机制研究
Annabelle G Hayes,Masoumeh G Shirazi,Anand Thiyagarajah et al.
Annabelle G Hayes et al.
Cabergoline-associated valvulopathy (CAV) is defined by the echocardiographic triad of moderate or severe regurgitation, valvular thickening and restricted valvular motion. While it is a well-described complication of dopamine agonist thera...
Macarena Contreras Angulo,Belén García Izquierdo,Laura Armengod Grao et al.
Macarena Contreras Angulo et al.
Summary: Systemic thrombotic microangiopathy (TMA) is a serious condition whose early treatment is essential to reduce morbidity and mortality. TMA with only renal involvement has been associated with tyrosine kinase inhi...
Gido Snaterse,Johannes Hofland,Bruno Lapauw
Gido Snaterse
11-oxygenated androgens are a class of steroids capable of activating the androgen receptor (AR) at physiologically relevant concentrations. In view of the AR as a key driver of prostate cancer (PC), these steroids are potential drivers of ...
Curcumin effects on Leydig cell functions and potential therapeutic uses [0.03%]
姜黄素对曲细精管间质细胞功能的影响及其潜在的治疗作用
Trinidad Raices,María Luisa Varela,Adriana María Belén Abiuso et al.
Trinidad Raices et al.
Curcumin has been ascribed with countless therapeutic effects, but its impact on testicular function has been scarcely researched. Leydig cells comprise the androgen-secreting population of the testis and may give rise to Leydig cell tumour...
Vineeth Sukrithan,Prachi Jain,Manisha H Shah et al.
Vineeth Sukrithan et al.
Objective: The treatment landscape for thyroid cancers has changed rapidly with the availability of kinase inhibitors against VEGFR, BRAF, MEK, NTRK, and RET. We provide an up-to-date review of the role of kinase inhibito...
Everything you ever wanted to know about cancer stem cells in neuroendocrine neoplasms but were afraid to ask [0.03%]
关于神经内分泌肿瘤干细胞的一切你想知道但不敢问的问题
While the role of cancer stem cells (CSCs) in tumorigenesis, chemoresistance, metastasis, and relapse has been extensively studied in solid tumors, such as adenocarcinomas or sarcomas, the same cannot be said for neuroendocrine neoplasms (N...