Potential pitfalls in diagnosis of immunotherapy-induced hypothalamic-pituitary-adrenal axis suppression [0.03%]
免疫治疗引起的下丘脑-垂体-肾上腺轴抑制的诊断陷阱
Darran Mc Donald,Rachel Katherine Crowley
Darran Mc Donald
Cellular specificity of androgen receptor, coregulators, and pioneer factors in prostate cancer [0.03%]
前列腺癌中雄激素受体、辅调节因子和先驱因子的细胞特异性
Damien A Leach,Rayzel C Fernandes,Charlotte L Bevan
Damien A Leach
Androgen signalling, through the transcription factor androgen receptor (AR), is vital to all stages of prostate development and most prostate cancer progression. AR signalling controls differentiation, morphogenesis, and function of the pr...
Hyponatraemia and the syndrome of inappropriate antidiuresis (SIAD) in cancer [0.03%]
低钠血症和不适当的抗利尿激素分泌综合征（SIAD）在癌症中的作用
D Mc Donald,M Sherlock,C J Thompson
D Mc Donald
Hyponatraemia is a common electrolyte abnormality seen in a wide range of oncological and haematological malignancies and confers poor performance status, prolonged hospital admission and reduced overall survival, in patients with cancer. S...
Regulatory genes in the androgen production, uptake and conversion (APUC) pathway in advanced prostate cancer [0.03%]
前列腺癌进展过程中调控雄激素合成、摄取和转化(APUC)途径相关基因的研究
Sean McSweeney,Hannah E Bergom,Anna Prizment et al.
Sean McSweeney et al.
The androgen receptor (AR) signaling pathway regulates the progression of prostate cancer (PC). Metastatic castration-resistant prostate cancer (mCRPC) patients generally receive AR-targeted therapies (ART) or androgen-deprivation therapies...
Pituitary tumors and the risk of other malignancies: is the relationship coincidental or causal? [0.03%]
垂体肿瘤和其他恶性肿瘤的关系是巧合还是因果关系？
Sandra Pekic,Marko Stojanovic,Vera Popovic
Sandra Pekic
Pituitary adenomas are benign neoplasms of the pituitary. The most prevalent are prolactinomas and non-functioning pituitary adenomas, followed by growth hormone- and ACTH-secreting adenomas. Most pituitary adenomas seem to be sporadic and ...
Pancreatic neuroendocrine neoplasms: survival trend analysis of a comprehensive center [0.03%]
胰腺神经内分泌肿瘤：综合性医疗中心的生存趋势分析
Sara Coelho,Cláudia Costa,Ana Paula Santos et al.
Sara Coelho et al.
Objectives: Therapeutic options for pancreatic neuroendocrine neoplasia (Pan-NEN) have increased over the last decade. We aim to understand the evolution of the prognosis of patients with diagnosis of Pan-NEN within a 12-...
Unusual presentation of lung carcinoma with pituitary metastasis: a challenging diagnosis and sodium management dilemmas [0.03%]
肺癌伴垂体转移的不典型病例报告：诊断困难及钠管理难题
Poh Shean Wong,Subashini Rajoo,Hairuddin Achmad Sankala et al.
Poh Shean Wong et al.
Summary: Pituitary metastasis (PM) is a rare complication of an advanced malignancy. Albeit rare, PM can be more detected and achieve a longer survival rate through frequent neuroimaging and newer oncology therapies. Lung...
Role of filamin A in the pathogenesis of neuroendocrine tumors and adrenal cancer [0.03%]
神经内分泌肿瘤和肾上腺癌发病机制中 Filamin A 的作用
Donatella Treppiedi,Rosa Catalano,Federica Mangili et al.
Donatella Treppiedi et al.
Cell cytoskeleton proteins are involved in tumor pathogenesis, progression and pharmacological resistance. Filamin A (FLNA) is a large actin-binding protein with both structural and scaffold functions implicated in a variety of cellular pro...
Visualization of the protein-protein interactions of hormone receptors in hormone-dependent cancer research [0.03%]
基于激素受体相互作用的依赖激素癌症研究可视化技术
Erina Iwabuchi,Yasuhiro Miki,Takashi Suzuki et al.
Erina Iwabuchi et al.
In hormone-dependent cancers, the activation of hormone receptors promotes the progression of cancer cells. Many proteins exert their functions through protein-protein interactions (PPIs). Moreover, in such cancers, hormone-hormone receptor...
Transient remission of hyperparathyroidism after fine-needle aspiration biopsy [0.03%]
细针抽吸活检后甲状旁腺功能亢进症的暂时缓解
Ana Rita Elvas,Andreia Martins Fernandes,Sara Reis et al.
Ana Rita Elvas et al.
Primary hyperparathyroidism (PHPT) is the unregulated overproduction of parathyroid hormone (PTH), resulting in abnormal calcium homeostasis. PHPT is most commonly caused by a single adenoma of the parathyroid gland, which can have an intra...